Streptomyces aurantiacus: GCM10017557_73720
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Entry
GCM10017557_73720 CDS
T07085
Symbol
ppsA
Name
(GenBank) phthiocerol synthesis polyketide synthase type I PpsA
KO
K15320
6-methylsalicylic acid synthase [EC:
2.3.1.165
]
Organism
sgm
Streptomyces aurantiacus
Pathway
sgm01059
Biosynthesis of enediyne antibiotics
sgm01100
Metabolic pathways
sgm01110
Biosynthesis of secondary metabolites
Module
sgm_M00829
3,6-Dimethylsalicylyl-CoA biosynthesis, malonyl-CoA => 6-methylsalicylate => 3,6-dimethylsalicylyl-CoA
Brite
KEGG Orthology (KO) [BR:
sgm00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01059 Biosynthesis of enediyne antibiotics
GCM10017557_73720 (ppsA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
sgm01008
]
GCM10017557_73720 (ppsA)
Enzymes [BR:
sgm01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.165 6-methylsalicylic-acid synthase
GCM10017557_73720 (ppsA)
Polyketide biosynthesis proteins [BR:
sgm01008
]
Polyketide synthase (PKS)
Iterative type I PKS
Fungal partially reducing PKS (PR-PKS)
GCM10017557_73720 (ppsA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Acyl_transf_1
KR
Ketoacyl-synt_C
KAsynt_C_assoc
PKS_DH_N
PP-binding
adh_short
Thiolase_N
adh_short_C2
Motif
Other DBs
NCBI-ProteinID:
BCL32513
UniProt:
A0A7G1PA03
LinkDB
All DBs
Position
complement(8380973..8386201)
Genome browser
AA seq
1742 aa
AA seq
DB search
MTAPEPIAVVGLACRFAGGIDSPEKFWSLLREGRDTIGEVPDDRWEWYGSLDRENAAAVG
GVTRYGAFLDDIKGFDADFFEVTPREAALMDPQQRIVLELAWEALEHAGIPPRDLAGSDA
GVFMGVGSDDYGRRMLEDLPRIEAWTGIGGAYCGVANRVSYVLDLHGPSVAVDTACSSSL
VSVHLAVQSLRDRECPVALAGGVLVMASPGLSLVLDAAGATAPDGRCKSFDASGDGYGRG
EGGGVVVLKRLSDARRDGDRVLALIRGSAVHQDGRTSGIMAPNGEAQAHLMRRTYERAGL
DPATVGYVEAHGTGTPAGDPLEARAMASVFGVDRPREQPCLIGSVKPNIGHLEAGAGIAG
VIKAVLALRHAEIPPSLNFHEPNPAVPWATSGLRVVTEPTPWPETAGGPRRAGVSGYGYG
GTIAHVVLEQAPDIGPPDRTLHDEVPEGRQPELALYPLSGAGEAAVREYAGKLADRLDAP
ASVAEVGHTLARRRSHLPHRATVVAAGQEQLAARLREFADTGDAPGLSTGSVQTSAGGGL
VWVFSGHGSQWTGMARELLAREPVFAETVDRLEPVFLAELGISPRAALLDDAAHPVDVVQ
PLIFAVQTSLSALWQERGLRPDAVLGHSVGEIAAAVTAGVLTLEQGARLVCRRSLLLRKV
AGKGAMAMVGLTAEEAELRLAGRRDVTVAITASPGSTVISGDIPAVADVSGRWRADGVAV
RAVDSDVAFHSPHMDPLLEDLAAAAADLTPSRARIPVYGTALDDPRDTAARDGRYWAANL
GGRVRFRQAVQAAVEDGYRLFLEVSPHPVVEHSVNETLDHLGVEDAFTTHSLRRRRPERE
TLLANLGQLYCHGAAVDWSRSWPDAAVADLPGVAWQRRPHWLQEPPPRSAAADRHDVTGH
TLLGGRTTLYGTTPARSWRTHLDHDSRPYPGDHPVRGVEIVPAAVLLNTFLTAAARGGTP
PDLADVALRVPVAVPLTRPRELQVVSQDGTIRLTSRPVGDADDDNGLITHTTATVEPRGA
LREAAPVATHEELPAGYVVDRLAELGVAAMGFPWRIDELRRADGALTAVVRADPASDEAP
ATWAPVLDAALSTASVVFPGPPVLRMPAHIRRVTLEGPSPALARITVRITGENVVDVDIS
DTDGAPVGRLAELRYGLLEDDTGAVASPRRLVHRMEWRPLGPTDPGSHQTVVLVGDDRDL
VKRLSRRLVGEGVPHRIASAPEELRASELTSGHTVVVVPAPGLSGEPVGRSSVRASWLLA
RTAQRLAAAASAQPPRLWCVTQGVRESADEASLSHAPLWGLGRVIAGEHPELWGGLVDIG
SSPRDVAGLVDLLGTAHGEDILAVREGRPEVARLALLEGEPVRPPVACRPDSTYLITGGL
GALGLEVAHWLAGRGARRIVLSGRRALPSRDQWDEVTDPRVLAQVESVKSLERMGTTVVT
VALDVSDADAAEKLLAPAALGLPPVRGVVHAAGVLDDRPLRSLDEASLRTVLRPKTEGAW
VLHGLFPPGSLDFLVLFSSCGQLLGLPGQSSYAAGNAFLDALAAHRRAVGDTGTVSFGWT
SWRGLGMSTSSEVIDAELAAHGTADVTAPEAFASWELAERYDLPYAAVLRTLPPEPGQRR
PPLLSEVPTDAPDDASDEETEAPWAGLAGDELRAFLTSEVSRQVAAETHLGASEVDPHRA
LTEMGLDSVMTVRIRRGLERQFRMPLPATLFWDRPTVHAVADLLAQRVGIPDPTPADEGS
TP
NT seq
5229 nt
NT seq
+upstream
nt +downstream
nt
atgacggcccccgaacccatcgcggtggtgggtctcgcctgccggttcgccggcggcatc
gactcgcccgagaagttctggtcactgttgcgcgagggccgggacaccatcggcgaggtg
cccgacgaccgctgggagtggtacggctccctcgaccgcgagaacgcggcggcggtgggc
ggtgtgacccggtacggcgcgttcctcgacgacatcaagggtttcgacgccgacttcttc
gaggtgaccccgcgcgaagccgccctcatggacccgcagcagcgcatcgtcctcgaactg
gcctgggaggcgctggagcacgccggtatcccgccgcgcgatctcgcgggctccgacgcc
ggggtgttcatgggtgtcgggtccgacgactacgggcgccgcatgctggaggacctgccc
cgcatcgaggcgtggaccggcatcggcggtgcctactgcggggtcgccaaccgggtgtcc
tacgtgttggatctgcacggcccgagcgtcgccgtggacaccgcgtgctcctcctcgctc
gtgtccgtccacctcgcggtgcagagcctgcgcgaccgtgagtgcccggtggcgctggcc
ggtggcgtactcgtgatggcgtcgcccggtctgtcactggtactggacgccgcgggggcg
acggctcccgacggacggtgcaagtcgttcgacgcgagcggcgacggctacgggcgtggt
gagggcggcggagtcgtcgtcctgaagcggctgtcggacgcccgccgcgacggtgaccgc
gtcctcgcactgatccggggcagtgcggtgcaccaggacgggaggaccagcggcatcatg
gcgcccaacggtgaggcgcaggcccacctgatgcgcaggacgtacgagcgtgccggtctg
gacccggcgacggtcggctacgtggaggcgcacggcacggggaccccggccggcgatccg
ctggaggcgcgggcgatggcctcggtcttcggtgtggaccggccgcgcgaacagccctgc
ctgatcgggtcggtgaagcccaacatcggtcatctggaggcgggggcgggcatcgccgga
gtcatcaaggcggtcctggcgctacggcacgccgagatccccccgagcctcaacttccac
gagcccaacccggccgtcccctgggcgacttccggcctgcgcgtggtcaccgaaccgacg
ccctggcccgagacggccggcggtccccggcgggcgggggtctccgggtacggctacggc
ggtacgatcgcgcacgtcgtcctggaacaggcaccggacatcggaccaccggaccggacg
ctccacgacgaggtgccggaaggcaggcagccggaactcgccctgtacccgctgtccggt
gcgggcgaagccgccgtgcgggaatacgcgggcaagctcgccgaccggctcgacgcaccg
gcttccgtcgcggaggtgggtcacaccctggcgcggcggcgctcccatctgccgcaccgt
gccaccgtcgtggccgccggccaggagcaactggccgcccggctgagggagttcgccgac
acgggtgacgcaccggggctgagtaccggatcggtgcagacgtcggccgggggcggtctg
gtctgggtgttctccgggcacggctcgcagtggaccggtatggcgcgcgagctgctcgcg
cgggagccggtgttcgcggagaccgtcgaccggctcgaacccgtgttcctggcggaactg
ggaatctcgccccgggcggcgctcctcgacgacgccgctcatccggtcgacgtggtgcag
ccgctgatcttcgccgtgcagacctcgctgagtgccctctggcaggagcgggggctgcgg
cccgacgccgttctcggccactcggtcggtgagatcgcggccgccgtgacggccggggtg
ctgacgctggaacagggcgcacggctggtgtgccggcgctcgctgctgctgcgcaaggtg
gcgggcaagggagccatggcgatggtgggcctgaccgccgaggaggccgaactccggctg
gccgggcgccgggacgtgaccgtggcgatcaccgcgtcaccaggttccaccgtgatctcc
ggggacattcccgccgtcgccgacgtcagcgggcggtggcgtgccgacggcgtcgcggtg
cgggccgtcgactccgacgtggcgttccacagtccgcacatggacccgctgctggaagac
ctggcggccgccgccgccgacctcacgccgtcccgcgccaggatccccgtctacgggacc
gccctggacgacccgcgggacaccgcggcgcgcgacggccgctactgggcggccaacctc
ggtggccgggtacggttccggcaggccgtgcaggctgccgtcgaggacggttaccggctc
ttcctcgaagtgtccccacacccggtggtcgaacactcggtcaacgagacactggaccac
ctcggtgtcgaggacgccttcaccacccactcgctgcgccgccgccgtcccgagcgcgag
acgctgctggccaacctcggtcagctgtactgccacggcgccgccgtggactggtcgcgc
tcctggcccgacgccgccgtggccgacctgccgggcgttgcctggcaacgccggccccac
tggctccaggaaccgccgccccgctcggccgccgccgaccgccatgacgtcaccgggcat
acgctgctgggcgggcggaccaccctgtacggcacgaccccggcacggagctggcggacg
catctcgaccacgacagccgcccctaccccggcgaccacccggtccgcggggtggagatc
gtccccgcggcggtcctgctcaacaccttcctcaccgccgccgcacggggcggcaccccg
ccggatctcgcggatgtggcgctgcgggtgccggtggcggtgccgctgacccggcctcgc
gaactccaggtcgtcagtcaggacggcacgatccggctcacctcccgtcccgtcggggac
gcggacgacgacaacggtctgatcacccacaccacggcgaccgtcgaaccgcgcggcgcg
ctccgcgaggcggccccggtcgccacccacgaggagctgccggccgggtacgtcgtggac
cgcctcgccgaactcggtgtcgccgccatgggctttccctggcggatcgacgaactacga
cgcgcggacggcgcgttgacggccgtggtccgtgccgacccggcatcggacgaggcacct
gcgacctgggccccggtcctggacgccgccctgtcgaccgcgtcggtggtgtttcccgga
ccgccggtgctgcgcatgcccgcacacatcaggcgggtcaccctcgaaggaccgtccccc
gcactggcccggatcaccgtgcggatcaccggcgagaacgtcgtcgacgtggacatcagc
gacacggacggggcccccgtgggccggctcgcggaactgcggtacggcctgctggaggac
gacacgggcgccgtcgccagtccgcgccgactggtccaccgtatggagtggcggccgctc
ggaccgacggatcccggctcgcaccagaccgtggtactcgtcggcgacgaccgcgatctg
gtgaagcgcctgagccggcgcctggtcggcgagggtgtgccgcaccggatcgcctccgct
cccgaggaactgcgtgcgagcgagctgacgagcggccacaccgtggtcgtcgtaccggcc
cccggcctgtccggtgagcccgtcggcaggtcatccgtacgagcgtcgtggctcctcgcg
cgaaccgcccaacgactcgccgcggccgcctccgcgcagccgcccaggctgtggtgcgtg
acccagggcgtgcgggagagtgccgacgaggcctccctgtcccacgcgccgctgtggggt
ctggggcgcgtcatcgccggggagcatccggagctgtggggcgggctggtggacatcggg
tcctcgccccgggacgtcgccgggctcgtcgatctcctcggcacagcccacggcgaggac
atcctggccgtacgcgaaggcaggccggaggtcgcgaggctggccctgctggagggcgag
ccggtacgcccgccggtcgcctgccgccccgacagcacctatctgatcacgggtgggctc
ggtgccctcggacttgaggtggcccactggctggccggtcgcggcgcgcgccggatcgtt
ctgtccgggcggcgggcgctgccgtcgcgggaccagtgggacgaggtcaccgatcctcgg
gtgctggcccaggtggagtcggtcaagtccctcgaacggatggggaccaccgtcgtcacc
gtcgcactggacgtctccgatgccgacgccgcggagaagctgctcgcgccggccgcgctc
ggcctgccgcccgtccggggtgtcgtgcacgcggcgggggtgttggacgaccgtccactg
cggtcgctcgacgaggcctctctgcgcacggtgctcaggccgaagaccgagggcgcatgg
gtgctgcacggcctcttcccgcccggcagcctggacttcctcgtgctgttctcgtcctgc
gggcaactgctcggcctgccgggtcagtccagttatgcggcaggcaacgccttcctcgac
gcgctcgcggcccaccgccgtgccgtcggggacacgggcaccgtcagtttcggctggacg
tcgtggcggggcctgggaatgtcgacctcctcggaggtcatcgacgccgaactggccgcg
cacggcaccgcggacgtgacggcccccgaggccttcgcctcctgggagctggccgagcgc
tacgacctcccgtacgccgccgtgctgcgcacgctgccgccggaaccggggcagcggcgg
cccccgctcctgagcgaggtgccgacggacgctccggacgacgcgtcggacgaggagacc
gaggcgccctgggccggcctcgcgggcgacgagctgcgcgcgttcctcacctcggaggtg
agccgccaggtcgccgccgagacccacctgggcgcgtccgaggtcgatccgcaccgggca
ctgaccgagatgggcctcgactcggtgatgaccgtacgcatccggcgaggcctggaacgg
cagttcaggatgccgctgccggcgacgctcttctgggaccggcccaccgtccacgcggtc
gcggacctcctcgcccagcgcgtcggcatccccgaccccactccggccgacgaagggagc
acgccatga
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