Streptomyces griseochromogenes: AVL59_40510
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Entry
AVL59_40510 CDS
T04729
Name
(GenBank) dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sgs
Streptomyces griseochromogenes
Pathway
sgs00790
Folate biosynthesis
sgs01100
Metabolic pathways
sgs01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sgs00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
AVL59_40510
Enzymes [BR:
sgs01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
AVL59_40510
6.3.2.17 tetrahydrofolate synthase
AVL59_40510
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
ANP55037
UniProt:
A0A1B1B8C8
LinkDB
All DBs
Position
complement(9314525..9316039)
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AA seq
504 aa
AA seq
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MSDHPGTSDTPDPLDAFEDLIAEETDRDPDLAVIEAGSRTLRTQGGSPQADVPTRPEDPE
VDKALREVETELATRWGETKLEPSVSRIAALMDVLGEPQRSYPSLHITGTNGKTSTARMI
EALLGAFELRTGRYTSPHVQSITERISLDGAPISAERFIETYQDIKPYVEMVDARQEHRL
SFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVITPIALDHTDRLGETP
GEIAGEKGGIIKQDATVILAQQPVDAAQVLLKKAVEVDATVAREGLEFGVVDRQVAVGGQ
LLTLRGLGGEYTEVYLPLYGAHQAHNAAVALAAVEAFFGVGAQRAEPLDIDTVRKAFAAV
SSPGRLEVVRRSPTIVLDAAHNPAGAEATAEAVREAFDFSRLIGVVGASADKNVRGLLEA
FEPIFAEIVVTQNSTPRAMDADELAAIAVEVFGEDRVQVEPRLPEALEAAITLAEEEGEF
AGGGVLVTGSVITVGEARLLLRKG
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgaccaccccggcaccagcgacacccccgaccccctcgacgccttcgaagacctc
atcgccgaagagaccgaccgcgaccccgacctcgcggtgatcgaggccggcagccgcacc
ctgcgcacccagggcggctcgccgcaggccgacgtacccacgcgtccggaggacccggag
gtcgacaaggccctgcgcgaggtcgagacggagctggccacccgctggggcgagaccaag
ctggagccctccgtcagccgcatcgccgccctgatggacgtactgggcgagccccagcgc
tcgtacccctccctccacatcacggggacgaacggcaagacctccaccgcccgcatgatc
gaggccctgctcggcgccttcgagctgcgcaccggccggtacaccagcccccacgtgcag
tcgatcaccgagcggatcagtctggacggcgccccgatctccgccgagcggttcatcgag
acgtaccaggacatcaagccgtacgtcgagatggtcgacgcgcggcaggagcaccggctg
tccttcttcgaggtgctcaccggcatggcgtacgcggccttcgcggacgcgccggtggac
gtcgccgtggtcgaggtcggcatgggcggcagctgggacgcgacgaacgtgatcgacggc
gatgtcgccgtgatcacccccatcgccctcgatcacaccgaccggctgggggagacgccg
ggggagatcgccggtgagaagggcggcatcatcaagcaggacgcgaccgtgatcctggcc
cagcagccggtggacgcggcgcaggtgctgctgaagaaggccgtcgaggtcgacgcgacc
gtggcccgggaagggctggagttcggggtcgtggaccggcaggtcgccgtcggcgggcag
ctgctcaccctgcgcggcctgggcggcgagtacaccgaggtgtatctgccgctgtacggc
gcccaccaggcgcacaacgcggccgtggcgctcgccgccgtggaggcgttcttcggcgtc
ggcgcgcagcgcgcggagccgctggacatcgacaccgtgcgcaaggccttcgcggccgtc
tcctcgccggggcggctggaggtcgtccggcggtcgcccacgatcgtcctggacgcggcc
cacaacccggcgggagcggaggccaccgccgaggcggtgcgggaggcgttcgacttcagc
cggctgatcggtgtggtcggggcgagcgccgacaagaacgtgcgggggctgctggaggca
ttcgagccgatcttcgccgagatcgtcgtcacgcagaactccacgccgcgtgcgatggac
gcggacgagctggccgcgatcgccgtcgaggtgttcggcgaggaccgggtccaggtcgag
ccgcggctgcccgaggccctggaggccgcgatcacgctggccgaggaggagggcgagttc
gcgggcggcggggtgctcgtcaccggctcggtcatcacggtgggcgaggcccgcctgctg
ctgaggaagggctga
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