Streptomyces glaucescens: SGLAU_22740
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Entry
SGLAU_22740 CDS
T03327
Symbol
kgd
Name
(GenBank) Multifunctional 2-oxoglutarate metabolism enzyme
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sgu
Streptomyces glaucescens
Pathway
sgu00020
Citrate cycle (TCA cycle)
sgu00630
Glyoxylate and dicarboxylate metabolism
sgu00785
Lipoic acid metabolism
sgu01100
Metabolic pathways
sgu01110
Biosynthesis of secondary metabolites
sgu01120
Microbial metabolism in diverse environments
sgu01200
Carbon metabolism
sgu01210
2-Oxocarboxylic acid metabolism
Module
sgu_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sgu_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sgu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SGLAU_22740 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
SGLAU_22740 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SGLAU_22740 (kgd)
Enzymes [BR:
sgu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SGLAU_22740 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SGLAU_22740 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SGLAU_22740 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SGLAU_22740 (kgd)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AIS00498
UniProt:
A0A089X977
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All DBs
Position
complement(5152152..5155952)
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AA seq
1266 aa
AA seq
DB search
MSPQSPSNASSISTDADQAGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYK
PGAAGAPAPAGPAAAGAAETTPQTPTPAPQPAAPAAPAQPAAPAAPAAPAPAAKAAAPSP
AKPAQPAQAPARPKAKAAPAAEAPEGPELVTLRGPAAAVAKNMNASLELPTATSVRAVPV
KLLFDNRIVINNHLKRARGGKISFTHLIGFAMVQAIKAMPSMNWSFGEKDGKPTLVKPPH
INLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRAREGKLTMDDFTGVTV
SLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYD
HRVIQGAASGEFLRTVANLLLGENNFYDDIFEALRIPYEPVRWLKDIDASHDDDVTKAAR
VFELIHSYRVRGHVMADTDPLEYRQRKHPDLDIVEHGLTLWDLEREFAVGGFAGKSMMKL
RDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERPHAKPEREEQLRILRRLNAAEAF
ETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVIGMAHRGRLNVLANIVGK
SYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVDPVL
EGVARAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVIN
NQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVI
DLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDYQ
GQLEKVFTEVREATSQPSAVETPDPQAEFPVAVGTAVTAEVVKRIAESQVNIPDHITVHP
RLLPQLQRRAAMVEDGTIDWGMGETLAIGSLLLEGVPVRLAGQDSQRGTFGQRHAVIIDR
ETGEEYTPLQYLAEEQARLNVYNSLLSEYAAMGFEYGYSLARPDALVMWEAQFGDFVNGA
QTVVDEFISSAEQKWNQTSGVVLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAMPTL
PSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTTGQFRPVIGDSSVDPAAV
KKVVFCAGKVYYDLEAERVKRGVKDTAIIRIERLYPLPGAELQAEIKKYPNAEKYLWAQE
EPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQEQLV
REVFEA
NT seq
3801 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaacgcatcgagcatctccaccgacgcagaccaagcgggc
aagaaccccgctgccgcgttcggtgccaacgagtggctcgtcgacgagatctatcagcag
tacctccaggacccgaattcggtagaccgcgcctggtgggacttcttcgccgattacaag
ccaggcgccgccggcgccccggctccggcgggacctgcggccgcgggggccgcggagacc
accccccagacgcccaccccggccccgcagcccgccgcaccggccgcaccggcgcaaccc
gccgccccggccgcccccgcggctcccgctcccgcggcgaaggccgcggccccctccccg
gccaagccggcgcaacccgcacaggcgcccgctcggccgaaggccaaggccgcgcccgcc
gcggaggccccggagggccccgagctggtcacgctgcgcggcccggccgccgcggtcgcc
aagaacatgaacgcctcgctggagctgccgaccgccacctcggtccgcgcggtgccggtg
aagctgctcttcgacaaccgcatcgtcatcaacaaccacctcaagcgggcccggggcggg
aagatctccttcacccacctcatcggcttcgcgatggtgcaggccatcaaggccatgccg
tcgatgaactggtcgttcggggagaaggacggcaagcccaccctcgtcaagcccccgcac
atcaacctcggcctcgccatcgacctggtcaagcccaacggcgaccgccagctcgtcgtc
gcggcgatcaagaaggccgagacgctgaacttcttcgagttctggcaggcctacgaggac
atcgtccgccgcgcccgtgagggcaagctgacgatggacgacttcaccggcgtcacggtc
tccctgaccaaccccggcggcctcggcaccgtccactccgtgccgcgcctgatgcccggc
cagtcggtgatcatgggcgtcggctccatggactacccggcggagttccagggcacctcc
caggacaccctgaacaagctcggcatctcgaaggtcatgacgctcacgtcgacctacgac
caccgggtgatccagggcgccgcctccggcgagttcctgcgcaccgtcgccaacctgctg
ctcggcgagaacaacttctacgacgacatcttcgaggcgctgcgcatcccctacgagccg
gtccgctggctcaaggacatcgacgcgtcccacgacgacgacgtcaccaaggccgcccgc
gtcttcgagctgatccactcctaccgggtccgcggccacgtcatggccgacaccgacccg
ctggagtaccgccagcgcaagcaccccgacctcgacatcgtcgagcacgggctgacgctg
tgggacctggagcgcgagttcgccgtcggcggcttcgccggcaagtcgatgatgaagctc
cgcgacatcctcggcgtgctgcgcgactcgtactgccgcaccaccggcatcgagttcatg
cacatccaggaccccaagcagcgcaagtggatccaggaccgcgtggagcgcccgcacgcc
aagccggagcgcgaggagcagctgcgcatcctgcgccgcctgaacgccgccgaggccttc
gagaccttcctgcagacgaagtacgtcggccagaagcgcttctcgctggagggcggcgag
tccgtcatcccgctgctggacgcggtgctggactcggccgccgagtcccgcctggacgag
gtcgtcatcggcatggcccaccgcggccgcctcaacgtcctcgccaacatcgtcggcaag
tcgtacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggc
tccggcgacgtgaagtaccacctgggcgccgagggcaccttcaccggcctcgacggcgag
cagatcaaggtgtcgctggtcgcgaacccgtcccacctggaggccgtcgacccggtcctg
gagggcgtcgcccgcgccaagcaggacatcatcaacaagggcggcacggacttcacggtc
ctgccggtggcgatccacggcgacgcggccttcgcgggccagggcgtggtggccgagacc
ctgaacatgtcgcagctgcgcggctaccgcacgggtggcaccgtccacatcgtgatcaac
aaccaggtcggcttcaccgccgccccggagtcctcgcgttcctccatgtacgcgacggac
gtggcccggatgatcgaggccccgatcttccacgtgaacggcgacgacccggaggcggtc
gtgcgcgtcgcgcgcctggccttcgagttccgccaggcgttcaacaaggacgtggtgatc
gacctcatctgctaccgccgccgcggtcacaacgagtcggacaacccggccttcacccag
ccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctgtacaccgagtcg
ctgatcggtcgcggcgacatcaccctggaggaggccgagcaggcgctccaggactaccag
ggccagctggagaaggtcttcaccgaggtccgcgaggccacctcgcagccgtccgcggtg
gagacgcccgacccgcaggccgagttcccggtcgccgtcggcaccgcggtcaccgccgag
gtcgtcaagcggatcgccgagtcccaggtcaacatccccgaccacatcaccgtccacccg
cggctgctcccgcagctccagcgccgggcggcgatggtcgaggacggcaccatcgactgg
ggcatgggcgagaccctcgccatcggctcgctgctcctggagggcgtcccggtccgcctg
gcgggccaggactcccagcgcggcaccttcggccagcgccacgcggtgatcatcgaccgt
gagacgggcgaggagtacacgccgctgcagtacctcgccgaggagcaggcgcggctcaac
gtctacaactccctcctctccgagtacgcggccatgggcttcgagtacggctactcgctg
gcccgcccggacgcgctcgtgatgtgggaggcgcagttcggcgacttcgtcaacggcgcc
cagacggtcgtggacgagttcatctcgtcggcggagcagaagtggaaccagacctccggt
gtggtcctgctcctcccgcacggctacgagggccagggcccggaccactcgtccgcccgc
ccggagcgcttcctccagctgtgcgcgcagaacaacatgacggtcgccatgccgaccctg
ccgtcgaactacttccacctcctgcggtggcaggtgcacaacccgcaccacaagccgctg
gtcgtcttcaccccgaagtcgatgctgcgcctgaaggccgccgcgtcgaaggcggaggag
ttcaccacgggccagttccgcccggtcatcggcgacagctcggtggacccggcggccgtg
aagaaggtcgtcttctgcgcgggcaaggtctactacgacctggaggccgagcgggtcaag
cggggcgtcaaggacaccgcgatcatccgcatcgagcggctgtacccgctgccgggtgcc
gagctccaggcggagatcaagaagtacccgaacgccgagaagtacctgtgggcgcaggag
gagccggcgaaccagggtgcgtggccgttcatcgcgctcaacctgatcgaccacctggac
ctggcggtcggcgcggacgtcccgcacggtgagcgcctgcgccgcatctcgcgcccgcac
tcctcgtccccggccgtgggttccgcgaagcggcaccaggccgagcaggagcagctggtg
cgtgaggtgttcgaggcgtga
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