Streptococcus pneumoniae JJA (serotype 14): SPJ_0299
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Entry
SPJ_0299 CDS
T00873
Name
(GenBank) dihydrofolate synthetase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sjj
Streptococcus pneumoniae JJA (serotype 14)
Pathway
sjj00790
Folate biosynthesis
sjj01100
Metabolic pathways
sjj01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sjj00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SPJ_0299
Enzymes [BR:
sjj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SPJ_0299
6.3.2.17 tetrahydrofolate synthase
SPJ_0299
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
LpxK
Motif
Other DBs
NCBI-ProteinID:
ACO19246
UniProt:
C1CC80
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Position
274477..275799
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AA seq
440 aa
AA seq
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MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVIHIGGTNGKGSTIAFLKKM
LEKLGLRVGVFSSPYLIHYTDQISINGESISEVRLEALMADYQSLLEGEAVANLQGTTEF
EIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILTGITTIGLDHVALLGDTLEAI
AEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPRLAYGTDYQVRHQESVVTGEVFD
YTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQEDGRELASNDFLGQALEETSWPGRL
EIVSRDPLMILDGAHNPHAIKALLVTLQERFADYHKEILFTCIKTKALGDMLDLLGAMPD
TELTLTHFADSRATDENVLKEAAKSRNLSYQDWHDFLEQNLTDKKEEKQTVRIVTGSLYF
LSQVRAYLMERKNENGYTKD
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaaagaaattgaaaataatcagtggattgctaactaccggacggaccaaccgcatttt
ggcttggaacgcatggtggaactgttagctttgcgtggcaatccccatctcaaactcaag
gttatccatatcggaggaaccaatggcaagggttcgaccattgcttttttgaaaaagatg
ctagaaaagctagggctgagagttggcgtgtttagctcgccctatctcattcattacaca
gaccagattagcatcaatggggaatcgatctcagaagtgaggctagaagctctcatggca
gactatcagtctttgctggagggagaagcggtcgccaatttacagggcacaaccgagttt
gagattatcacagccctagcctatgactactttgcctcagagcaagtagatgtggctatc
atggaagttggcatgggtggacttttggatagtaccaatgtctgtcagcccattttgaca
ggaattacaactattggcttggatcatgtggccctacttggtgacaccttggaggccata
gcagagcagaaggcaggtattatcaaacaagggatgcccttggtaacagggcgtattgct
ccagaagccttggctgtgattgaccgcattgcggaagggaaagatgcgccgagacttgcc
tacgggacagattatcaggttcgtcatcaagaaagtgtggtgacaggggaagtctttgac
tatacaagtgctgtcagacaaggtcgcttccagactagcctgcttggtttgtaccaaata
gagaatgctgggatggccatagctttacttgatactttttgtcaagaagatggtcgagag
ctagcaagcaatgattttcttggtcaagccttggaagaaacaagttggccagggcgtttg
gaaatcgtgtcaagagatcccttgatgattttggatggagcccacaatccccatgctatc
aaggccttgttggtaaccttgcaagaacgttttgcggattatcataaggaaatcctcttc
acttgtatcaaaaccaaggccttgggggatatgttggacttgctgggagccatgccagat
accgagcttactctaacacattttgcggatagtcgggcgacggatgaaaacgtgctgaaa
gaggcagctaagtctagaaatctcagctaccaagattggcatgattttctagagcagaat
ttgacagataaaaaagaagagaaacaaacagttaggattgtcacaggttccttgtatttc
ttgagccaagtgagggcctatctgatggagaggaagaacgagaatggatacacaaaagat
tga
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