Streptomyces laculatispora: P8A22_26270
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Entry
P8A22_26270 CDS
T09657
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
slai
Streptomyces laculatispora
Pathway
slai00790
Folate biosynthesis
slai01100
Metabolic pathways
slai01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
slai00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
P8A22_26270
Enzymes [BR:
slai01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
P8A22_26270
6.3.2.17 tetrahydrofolate synthase
P8A22_26270
BRITE hierarchy
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
WLQ43123
LinkDB
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Position
5924410..5925933
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AA seq
507 aa
AA seq
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MSEPRPSDRHDASDSDETFAEIVDEATQRDPDLAVIEAGSRTLRAASGPPQADEVPARPT
DPEVDRALRAVEQELAGRWGETKLEPSVARIAALMDVLGDPQRAYPSIHITGTNGKTSTA
RMIEGLLGAFDLRTGRYTSPHVQSITERISLDGAPMDAERFVETYEDIKPYVEMVDAQQP
YRLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDATVAVVTPISLDHTDRLG
STPGEIAVEKAGIIKQGATVILAQQPVDAAQVMLKKAVAADATVAREGMEFGVVSREVAV
GGQLLTLRGLGGEYDNIFLPLYGAHQAHNAVVALCAVEAFFGIGAEQSGSLDADIIRKAF
AAVLSPGRLEVVRSSPTVVLDAAHNPAGARAAAEGLSEAFGFSRLIGVVGASGDKDVRGL
LEAFEPIFAEVVITQNSSGRAMDADALATVAVEVFGNERVQVEPRLDDALEAAITLAEEE
DEYAGAGVLVTGSVITVGEARLLLGRR
NT seq
1524 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagccccgcccttccgaccggcacgacgcgtccgactccgacgagaccttcgcg
gagatcgtcgacgaagcgacccagcgcgaccccgacctggcggtgatcgaggccgggagc
cggacgctgcgcgccgcctccgggccgccccaggcggacgaggtccccgcccgccccacc
gatccggaggtggacagggcgctgcgcgcggtggagcaggagctcgccgggcgctgggga
gagaccaagctggagccgtccgtggcgcgcatcgccgcgctgatggacgtgctcggcgac
ccgcagcgcgcgtacccctcgatccacatcaccggtaccaacggcaagacgagcacggcc
cgcatgatcgagggcctgctcggcgccttcgacctgcgcaccggccgctacacctcgccg
cacgtccagtcgatcaccgagcggatcagcctggacggcgccccgatggacgccgagcgg
ttcgtcgagacctatgaggacatcaagccgtacgtcgagatggtcgacgcgcagcagccc
taccggctctccttcttcgaggtgctcaccggcatggcgtacgcggcgttcgccgacgcg
ccggtcgatgtcgccgtcgtcgaggtcggcatgggcggcagctgggacgcgaccaacgtc
atcgacgccacggtcgcggtcgtcaccccgatctccctggaccacaccgaccggctgggc
tccacacccggtgagatcgcggtggagaaggccgggatcatcaagcagggtgcgacggtc
atcctggcccagcagccggtcgacgccgctcaggtgatgctgaagaaggccgtcgcggcc
gacgcgacggtggcccgcgagggcatggagttcggtgtcgtctcccgggaggtcgcggtc
ggcgggcagctgctgacgctgcgcggtctcggcggtgagtacgacaacatcttccttccg
ctgtacggcgcccaccaggcgcacaacgccgtggtggcgctctgcgccgtcgaggcgttc
ttcgggatcggcgccgagcagtccggatcgctcgacgccgacatcatccgcaaggccttc
gccgcggtgctctcgcccggccgcctcgaggtcgtccgctccagtccgacggtcgtcctg
gacgccgcccacaacccggccggcgcccgcgccgccgccgaggggctctccgaggcgttc
ggcttctcccggctgatcggtgtggtcggtgccagtggcgacaaggacgtccgggggctc
ctggaggccttcgagccgatcttcgccgaggtcgtcatcacccagaactccagcggccgc
gcgatggacgcggacgccctggccaccgtcgccgtcgaggtcttcggcaacgagcgggtc
caggtcgaaccccgtctcgacgacgcgctggaggcggcgatcactctcgccgaggaagag
gacgagtacgcgggcgccggggtgctggtgaccggatccgtgatcacggtcggcgaggcc
cggctgcttctgggaaggcgctga
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