Streptomyces leeuwenhoekii: sle_19850
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Entry
sle_19850 CDS
T04414
Symbol
sle_19850
Name
(GenBank) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1
KO
K03526
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:
1.17.7.1
1.17.7.3
]
Organism
sle
Streptomyces leeuwenhoekii
Pathway
sle00900
Terpenoid backbone biosynthesis
sle01100
Metabolic pathways
sle01110
Biosynthesis of secondary metabolites
Module
sle_M00096
C5 isoprenoid biosynthesis, non-mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
sle00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
sle_19850 (sle_19850)
Enzymes [BR:
sle01000
]
1. Oxidoreductases
1.17 Acting on CH or CH2 groups
1.17.7 With an iron-sulfur protein as acceptor
1.17.7.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)
sle_19850 (sle_19850)
1.17.7.3 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin)
sle_19850 (sle_19850)
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Motif
Pfam:
GcpE
zf-RING_7
Aldolase
DUF6310
Motif
Other DBs
NCBI-ProteinID:
CQR61446
UniProt:
A0A0F7VWZ4
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All DBs
Position
chromosome:complement(2442299..2443456)
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AA seq
385 aa
AA seq
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MTAISLGMPSVPTKLAERRKSRQIQVGSVAVGGDAPVSVQSMTTTRTSDIGATLQQIAEL
TASGCQIVRVACPTQDDADALPVIARKSQIPVIADIHFQPKYVFAAIEAGCAAVRVNPGN
IKKFDDQVREIARAAKDHGTPIRIGVNAGSLDKRLLQKYGKATPEALVESALWEASLFEE
HDFRDIKISVKHNDPVVMIEAYRQLAEACDYPLHLGVTEAGPAFQGTIKSAVAFGALLSQ
GIGDTIRVSLSAPPAEEVKVGIQILESLNLRQRGLEIVSCPSCGRAQVDVYKLAEEVTAG
LTGMDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESKIVETLIE
EAMKLAEQMEKDGVASGEPSVSVAD
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atgactgcgatttctctcggcatgccgtccgttccgaccaagctcgccgagcgccgcaag
agccggcagatccaggtcgggtccgtggcggtcggcggggacgcgcccgtctcggtgcag
tcgatgaccacgacccgtacgtcggacatcggggccacgctccagcagatcgcggagctg
acggcgtccggctgccagatcgtccgggtggcctgccccacgcaggacgacgccgacgcg
ctcccggtcatcgcgcgcaagtcccagatccccgtcatcgcggacatccacttccagccc
aagtacgtcttcgccgcgatcgaggcgggatgcgcggcggtgcgggtcaacccgggcaac
atcaagaagttcgacgaccaggtcagggagatcgcccgggcggccaaggaccacggcacc
ccgatccgtatcggggtcaacgcgggctccctggacaagcggctgctgcagaagtacggc
aaggcgacccccgaggcgctggtcgagtcggccctgtgggaggcgtccctcttcgaagag
cacgacttccgcgacatcaagatctccgtcaagcacaacgacccggtcgtgatgatcgag
gcctaccggcagctcgccgaggcgtgcgactacccgctccacctgggcgtcaccgaggcc
ggtcccgccttccagggcacgatcaagtcggcggtcgccttcggtgccctgctctcccag
ggcatcggcgacaccatccgcgtctccctgtcggcgccgcccgccgaggaggtcaaggtc
ggcatccagatcctggagtcgctcaacctgcgccagcgcggcctggagatcgtctcctgc
ccgtcctgcggccgcgcccaggtcgacgtctacaagctcgccgaggaagtcaccgccggc
ctgaccggcatggacgtcccgctgcgcgtcgccgtgatgggctgcgtggtcaacggcccc
ggcgaggcccgcgaggccgacctcggcgtcgcctccggcaacggcaagggccagatcttc
gtcaagggcgaggtcatcaagaccgtccccgagtccaagatcgtcgagacgctcatcgag
gaggccatgaagctggccgagcagatggagaaggacggcgtggcctccggcgagccgtcg
gtgtccgtcgccgactga
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