Streptomyces leeuwenhoekii: sle_45820
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Entry
sle_45820 CDS
T04414
Symbol
sle_45820
Name
(GenBank) Pyruvate dehydrogenase E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sle
Streptomyces leeuwenhoekii
Pathway
sle00280
Valine, leucine and isoleucine degradation
sle00640
Propanoate metabolism
sle00785
Lipoic acid metabolism
sle01100
Metabolic pathways
sle01110
Biosynthesis of secondary metabolites
sle01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
sle_45820 (sle_45820)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
sle_45820 (sle_45820)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
sle_45820 (sle_45820)
Enzymes [BR:
sle01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
sle_45820 (sle_45820)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
CQR64040
UniProt:
A0A0F7VWA3
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Position
chromosome:complement(5389109..5390176)
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AA seq
355 aa
AA seq
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MSGDGIRLLTPEGERVPHPDYPSDAGPEELRALYRDMALARRVDAEGVTLQRQGELGLWP
SLLGQEAAQVGSVRALREGDRVFPSYREHAVALGRGVDPLALMRLFRGVDHGAWDPEAHD
FHLYTLVIGSQTLHATGYACGMAKDGADAAVIVYFGDGATSQGDVSEAFNFAAVWDAPIV
FFCQNNQWAISEPNERQTRVPLHQRAQGFGFPGVRVDGNDVLAVQAVTRAALDHARSGRG
PFLIEAFTYRMGAHTTSDDPSRYRDAAEVESWRAKDPLLRLERLLRREGAADDAFFAEVA
VAGEALAARVREGVRAMASPAPEEMFDHVYAEAHTGVDRERAAFAAYQAAFAEEG
NT seq
1068 nt
NT seq
+upstream
nt +downstream
nt
gtgagcggcgacggcatacggctgctcacgcccgagggcgagcgcgtgccgcaccccgac
tacccgtcggacgccgggccggaggaactgcgcgcgctctaccgggacatggccctggcc
cgccgcgtggacgccgagggggtcaccctccagcgccagggcgaactgggcctgtggccc
tcactgctcggccaggaggcggcgcaggtcggttcggtacgggcgctgcgcgagggcgac
cgggtcttcccgagctaccgcgaacacgccgtggcgctgggccgcggggtcgatccgctg
gccctgatgcggctgttccgcggggtcgaccacggggcctgggacccggaggcgcacgac
ttccacctgtacacgctggtcatcggctcgcagacgctgcacgccaccggttacgcctgc
gggatggccaaggacggcgcggacgcggcggtcatcgtctacttcggcgacggcgcgacc
agccagggcgatgtctcggaggcgttcaacttcgccgccgtgtgggacgccccgatcgtg
ttcttctgccagaacaaccagtgggcgatctccgaacccaacgagcgccagacccgcgtc
ccgctgcaccagcgcgcccagggcttcggcttccccggggtgcgcgtggacggcaacgac
gtgctcgccgtgcaggcggtcacccgggccgcgctggaccacgcgcgttcgggccgcggg
ccgttcctgatcgaggcgttcacctaccggatgggcgcccacaccacctcggacgacccg
tcccggtaccgggacgcggccgaggtggagagctggcgggccaaggacccgctgctgcgg
ctggagcgcctgctgcgccgcgagggcgcggccgacgacgccttcttcgccgaggtggcg
gtggccggcgaggcgctggccgcccgcgtccgggagggcgtgcgcgccatggcctccccc
gcccccgaggagatgttcgaccacgtctacgcggaggcccacacgggggtggaccgcgaa
cgcgccgcgttcgcggcctaccaggcggccttcgccgaggagggctga
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