Streptomyces liangshanensis: HA039_23395
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Entry
HA039_23395 CDS
T07519
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
slia
Streptomyces liangshanensis
Pathway
slia00790
Folate biosynthesis
slia01100
Metabolic pathways
slia01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
slia00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HA039_23395
Enzymes [BR:
slia01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HA039_23395
6.3.2.17 tetrahydrofolate synthase
HA039_23395
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
DUF1491
Motif
Other DBs
NCBI-ProteinID:
QIQ04829
UniProt:
A0A6G9H3G3
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All DBs
Position
5397394..5398908
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AA seq
504 aa
AA seq
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MSEQRPSDQPGEYDDFDEIVAAETDRDPDLAVIEAGSRTLRAQAGPQRGDEVPSRPEDPE
VDKALRAVEQELGGRWGETKLDPSLGRIEALMDVLGDPQRAYPTIHITGTNGKTSTARMI
EALLSAFELRTGRYTSPHVQSVTERISLDGAPIPAERFVETYDDIKAFVEMVDAAQEHRL
SFFEVLTGMAYAAFADAPVDVAVIEVGMGGSWDATNVIDASVAVVTPIDLDHTDRLGSTP
GEIAVEKSGIIKAGATVVLAQQPVDAAQVMLKKAVEVDATVAREGLEFGIVAREIAVGGQ
LLTLRGLGGEYEQVFLPLYGAHQAHNAAVALAAVEAFFGVGAEHARPLDMDTVRKAFASV
SSPGRLEVMRRSPTVVLDAAHNPAGARAAAEGITESFGFSRLIGVIGSSEGKDVRGVLEA
LEPICTELVVTQNSSHRAMDVDELAAVAVEVFGDERVVVEARLDDALEAAITLAEDDAEF
AGAGVLVTGSVITVGEARLLLGRR
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagcagcgtccttccgaccagcccggtgagtacgacgactttgacgagatcgtc
gcggccgagaccgaccgagaccccgacctcgccgtgatcgaggcgggcagccgcaccctg
cgcgcccaggccgggccgcagcggggtgacgaggtgccgtcccgtcccgaggaccccgag
gtggacaaggcgctgcgcgccgtcgagcaggagctcggcgggcgctggggggagacgaag
ctcgacccctcgctggggcggatcgaggccctgatggacgtgctgggcgacccccagcgc
gcgtacccgacgatccacatcaccgggaccaacggcaagacgtccacggcccgcatgatc
gaggcgctgctgagcgcgttcgagctgcggaccgggcggtacacgagcccgcacgtccag
tcggtcaccgagcggatcagcctggacggcgccccgatccccgccgagcgcttcgtcgag
acgtacgacgacatcaaggcgttcgtcgagatggtcgacgcggcgcaggagcaccggctg
tcgttcttcgaggtgctcacgggcatggcgtacgcggcgttcgcggacgcgccggtggac
gtggcggtcatcgaggtcgggatgggcggcagctgggacgcgacgaacgtcatcgacgcg
tcggtcgcggtggtcacccccatcgacctggaccacacggaccggctcgggtcgacgccc
ggcgagatcgccgtggagaagtccgggatcatcaaggcgggcgcgacggtcgtcctggcg
cagcagccggtggacgcggcgcaggtgatgctgaagaaggccgtcgaggtcgacgcgacg
gtggcccgggagggcctggagttcgggatcgtcgcccgggagatcgcggtcggcgggcag
ctgctgacgctgcgcggcctcggcggtgagtacgagcaggtgttcctcccgctgtacggc
gcgcaccaggcgcacaacgcggcggtggcgctggcggcggtggaggcgttcttcggggtc
ggcgcggagcacgcgcgcccgctggacatggacacggtccgcaaggcgttcgcgtcggtg
tcctcgccgggccgcctggaggtgatgcggcgttcgcccacggtggtgctggacgcggcg
cacaacccggcgggcgcgcgggcggcggccgagggcatcaccgagtcgttcgggttcagc
cggctgatcggggtgatcgggtcgagcgagggcaaggacgtgcgcggggtgctggaggcg
ctggagccgatctgtacggagctggtggtcacgcagaactccagccaccgcgcgatggac
gtggacgagctggccgcggtggccgtcgaggtgttcggcgacgagcgggtggtggtcgag
gcgcggctggacgacgcgctggaggcggcgatcacgctcgccgaggacgacgcggagttc
gccggggccggtgttctggtgacgggttccgtcatcacggtgggcgaggcccggctgctt
ctgggaaggcgctga
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