Streptomyces lividans: SLIV_24605
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Entry
SLIV_24605 CDS
T03222
Name
(GenBank) folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
slv
Streptomyces lividans
Pathway
slv00790
Folate biosynthesis
slv01100
Metabolic pathways
slv01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
slv00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SLIV_24605
Enzymes [BR:
slv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SLIV_24605
6.3.2.17 tetrahydrofolate synthase
SLIV_24605
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AIJ15838
LinkDB
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Position
5495099..5496622
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AA seq
507 aa
AA seq
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MSDNPGQNDQPDPSAPLDSFDEIIDAETTRDPDLAVIEAGSRTLRTQGGPPEADVPGRPE
DPEVDAALRAVETELAGRWGETKLEPSVTRIAALMDVLGEPQRSYPSIHITGTNGKTSTA
RMIEALLGAFDLRTGRYTSPHVQSITERISLDGAPISAERFIETYEDIKPYVEMVDAQQE
YRLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVVTPIDLDHTDRLG
GTPGEIAVEKAGIVKQDATVILAQQPVDAAQVMLKKAVDVNATVAREGLEFGVVAREVAV
GGQLVTLRGLGGEYTEVYLPLHGAHQAHNAAVALAAVEAFFGVGAQRPEPLDVDTVRKAF
ASVASPGRMEVVRRSPTVVLDAAHNPAGARVTAEAVGEAFQFSRLIGVVGASADKNVRGL
LEAFEPVFAEVVVTQNSSHRAMDADELAAVAVEVFGDDRVQVEPRLPDALEAAITLAEEE
GEFAGGGVLVTGSVITVGEARLLLRRG
NT seq
1524 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgacaaccccggccagaacgaccagcccgacccctccgcccccctcgactccttc
gacgagatcatcgacgcggagaccacccgcgaccccgacctcgccgtcatcgaggccggc
agccgcaccctgcgcacccagggcggccccccggaggccgacgtccccgggcgcccggag
gaccccgaggtggacgcggccctgcgcgccgtcgagacggagctggccggccgctggggc
gagaccaagctggagccgtccgtcaccaggatcgccgcgctgatggacgtactgggcgag
ccgcagcgctcgtacccctccatccacatcaccgggaccaacggcaagacctccaccgcc
cgcatgatcgaggccctgctcggcgccttcgatctgcgcaccgggcggtacacctcgccg
cacgtgcagtcgatcaccgagcggatcagcctggacggggcgccgatctccgccgagcgg
ttcatcgagacctacgaggacatcaagccgtacgtcgagatggtcgacgcgcagcaggag
taccggctgtccttcttcgaggtgctgaccggcatggcgtacgccgccttcgccgacgca
cccgtggacgtggccgtcgtcgaggtcgggatgggcggctcctgggacgccaccaacgtc
atcgacggggacgtggccgtcgtcacccccatcgacctggaccacaccgaccggctcggc
gggacgcccggcgagatcgcggtcgagaaggccggcatcgtcaagcaggacgccaccgtc
atcctggcccagcagccggtggacgcggcgcaggtgatgctgaagaaggccgtcgacgtc
aacgccaccgtggcccgcgaggggctggagttcggcgtcgtggcccgcgaggtcgccgtc
ggcgggcagctggtcaccctgcgcggactgggcggcgagtacaccgaggtctacctgccg
ctgcacggcgcccaccaggcgcacaacgcggcggtcgcgctggccgccgtcgaggcgttc
ttcggcgtcggcgcgcagcgtcccgagccgctggacgtcgacaccgtgcgcaaggccttc
gcctccgtcgcctcgccggggcggatggaggtggtgcggcgctcgccgaccgtggtcctc
gacgccgcgcacaacccggccggcgcccgggtcaccgccgaggcggtgggggaggccttc
cagttcagccgcctcatcggggtggtcggtgccagcgccgacaagaacgtgcgggggctc
ctcgaagccttcgagccggtcttcgccgaggtcgtcgtcacccagaactccagccaccgc
gcgatggacgccgacgagctggccgcggtcgccgtcgaggtcttcggcgacgaccgcgtc
caggtcgagccgcggctgccggacgccctggaggccgcgatcacgctggccgaggaggag
ggcgagttcgccggcggcggtgtgctcgtcaccggttccgtcatcaccgtcggcgaggcc
cgactgctcctgaggaggggctga
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