Serratia marcescens subsp. marcescens Db11: SMDB11_2731
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Entry
SMDB11_2731 CDS
T03985
Symbol
folC
Name
(GenBank) bifunctional folylpolyglutamatesynthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
smac
Serratia marcescens subsp. marcescens Db11
Pathway
smac00790
Folate biosynthesis
smac01100
Metabolic pathways
smac01240
Biosynthesis of cofactors
Module
smac_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
smac00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SMDB11_2731 (folC)
Enzymes [BR:
smac01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SMDB11_2731 (folC)
6.3.2.17 tetrahydrofolate synthase
SMDB11_2731 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
CDG13302
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Position
complement(2889380..2890672)
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AA seq
430 aa
AA seq
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MNPSSVTGLMQNHQIPQATSPLSSWLYYLERLHSQAIELGLERVQRVAAHLDLLTPAPTV
FTVAGTNGKGTTCRTLEAILLAAGLRVGVYSSPHLVRYTERVRIQGEELSEAEHSRSFAA
IEAGRGETSLTYFEFGTLSALQLFKQARLDVVILEVGLGGRLDATNIVDPSVAVITSIAL
DHTDWLGNDRESIGREKAGIFRSGKPAVVGEPDMPDSIRQVAETLGAPLYRRGEAWSFSE
QGDRWQWQGGDTQLTDLPTPNIPLANAATALAALNCSPLEIDERAIFTGLQQATLPGRFQ
IVRREPMLILDVAHNPHAAGYLAGRLAKLPRDGGKVRAVVGMLSDKDIAGTLACLSEQVD
EWYCAPLDGPRGASVEQLAQHLTEPRRFNDVETAWRQAMQDADKQDIVIVCGSFHTVAQV
MAALDEMRGV
NT seq
1293 nt
NT seq
+upstream
nt +downstream
nt
atgaacccaagttcagtgacgggactcatgcaaaaccaccaaattccccaagccacgtcg
ccattgagctcgtggctttactatctggaacgtctgcacagccaggcgatcgaactcggt
cttgagcgcgtacagcgcgtcgcggcgcatctggatttactgacccccgctcctacggtg
ttcaccgttgccggcaccaacggcaaaggcacgacctgtcgtaccctcgaagccattctg
ctggccgccggcctgcgcgtcggcgtctacagttcgccgcatctggtgcgctataccgaa
cgcgtgcgcattcagggggaagagctgagcgaagcagagcatagccgctcgttcgccgcc
attgaagccggccgcggcgaaacgtcgctgacctatttcgaattcggcaccctgtcggcg
ctgcagctgttcaaacaggcgcggctcgacgtggtgatcctggaagtgggcctgggcggg
cgtctcgacgccaccaatatcgtcgatccgagcgtggcggtgatcaccagcattgcgctc
gatcataccgactggctgggcaacgatcgcgaaagcatcggccgtgaaaaggccggtatt
ttccgtagcggcaagccggcggtggtgggcgaacccgacatgccggacagcattcgccag
gtcgccgaaacgctgggcgcaccgctgtatcgccgcggtgaagcctggagcttcagcgag
cagggcgatcgctggcagtggcagggcggcgacacgcagctgaccgatctgccgacgccg
aacataccgctggccaacgccgctaccgcgctggcggcgctgaactgttccccgctggaa
atcgacgaacgcgcgatcttcaccgggctgcagcaggcgacgctgccggggcgtttccag
atcgtgcggcgggagccgatgctgatcctcgacgtggcacacaacccgcacgccgccggc
tatctggccgggcgtctggccaagctgccgcgcgacggcggcaaggtacgcgcggtggtg
ggcatgctgtccgacaaggacatcgccggcacgctggcctgcctcagcgagcaggtggat
gaatggtactgcgcaccgctcgacgggccgcgcggtgccagcgtcgaacagctggcgcag
catctgacggaaccgcgccgctttaatgatgtcgaaactgcctggcggcaggctatgcag
gatgctgataaacaggatattgtgatcgtctgtggatcgttccacaccgtggcgcaggtg
atggcggcgttagacgagatgcggggagtgtga
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