Streptomyces malaysiensis: SMALA_2613
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Entry
SMALA_2613 CDS
T05189
Name
(GenBank) folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
smal
Streptomyces malaysiensis
Pathway
smal00790
Folate biosynthesis
smal01100
Metabolic pathways
smal01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
smal00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SMALA_2613
Enzymes [BR:
smal01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SMALA_2613
6.3.2.17 tetrahydrofolate synthase
SMALA_2613
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
ATL82847
UniProt:
A0A291SPQ6
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Position
complement(3321122..3322636)
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AA seq
504 aa
AA seq
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MSEERPKNESDESDEFDEIVGAETDRDPDLAVIEAGSRTLRAQSGPPQGDGIPTRPADPE
VDRALREVEGELAKRWPETKLEPSLVRIESLMDILGSPQRAYPSIHITGTNGKTSAARMI
ESLLGAFELRTGRYTSPHVQSITERISLDGAPISAERFIETYQDIRPYIEMVDAQQEHRL
SFFEVLTGMAYAAFADAPVDIAVVEVGMGGSWDATNVIDAGVAVIMPISLDHTDRLGTTP
EQIATEKAGIVKQDATVVLAQQPVEAASVVLKRAVEVDATVAREGMEFGVLSREVAVGGQ
LLTLRGLGGEYPDVFLPLHGAHQAHNAAMALAAVEAFFGVGSQHARTLDIDTVRSAFASV
TSPGRMEVVRRSPTVVLDAAHNPAGARAAAEAVTESFDFSRLVGVVGTSDDKDVRGLLEA
FEPIFAEVVVTRNSSHRSMDPDELAAIAVEIFGADRVQVEPRLDDALEEAITLAEEEGEY
AGAGVLVTGSVVTVGEARLLLGKG
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgaggagcgccccaagaacgagtccgacgagtccgacgagttcgatgagatcgtc
ggagccgagaccgaccgcgaccccgatctggcggtgatcgaggccggcagccggacgctg
cgtgcgcagtccgggccgccgcagggggacggcatccccacccgcccggccgaccccgag
gtggaccgcgccctgcgggaggtggagggcgagctggccaagcgctggccggagaccaag
ctggagccgtcgctggtgcggatcgagtccctgatggacatcctcggctcgccgcagcgg
gcctacccctcgatccacatcaccggtacgaacggcaagaccagcgccgcccgcatgatc
gagtcgctgctgggcgccttcgagctgcgcaccggccgctacaccagcccccatgtccag
tcgatcaccgagcggatcagcctggacggcgcgccgatctcggccgagcggttcatcgag
acgtaccaggacatccggccgtacatcgagatggtcgacgcccagcaggagcaccggctg
tccttcttcgaggtgctcaccggcatggcgtacgcggccttcgcggacgcgcccgtggac
atcgcggtggtcgaggtcggcatgggcggctcctgggacgccaccaatgtgatcgacgcg
ggcgtagcggtgatcatgccgatctcgctggaccacaccgaccggctgggcaccactccg
gagcagatcgccacggagaaggccgggatagtgaagcaggacgccaccgtggtgctcgcg
cagcagccggtggaggccgcctccgtggtgctcaagcgcgcggtcgaggtggacgccacg
gtcgcccgtgagggcatggagttcggtgtgctgtcccgggaggtggcggtcggcggtcag
ctgctgacgctgcgcggcctcggcggggagtacccggatgtcttccttccgctgcacggc
gcccaccaggcgcacaacgcggcgatggcgctcgcggccgtcgaggcgttcttcggcgtc
ggctcccagcacgcccgcacgctcgacatcgacaccgtccgctccgccttcgcctccgtg
acctcgcccggccggatggaggtcgtgcgccgcagccccaccgtggtgctggacgccgcg
cacaaccccgcgggcgcccgcgccgcggccgaggcggtcaccgagtccttcgacttcagc
cggctggtcggcgtggtcgggacgagcgacgacaaggatgtgcgcggtctgctggaagcc
ttcgagccgatcttcgcggaggtggtggtgacccgcaattccagccatcgctccatggac
ccggacgagctggccgcgatcgccgtcgagatcttcggcgccgaccgggtgcaggtcgag
ccgcggctggacgacgccctggaggaggccatcaccctggcggaggaagagggcgaatac
gccggggcgggtgttctggtgaccgggtcggtggtcacggtcggcgaggcccggctgctt
ctgggaaagggctga
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