Streptococcus mitis: smi_0280
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Entry
smi_0280 CDS
T01173
Symbol
sulB
Name
(GenBank) dihydrofolate synthetase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
smb
Streptococcus mitis
Pathway
smb00790
Folate biosynthesis
smb01100
Metabolic pathways
smb01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
smb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
smi_0280 (sulB)
Enzymes [BR:
smb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
smi_0280 (sulB)
6.3.2.17 tetrahydrofolate synthase
smi_0280 (sulB)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Polysacc_deac_2
Motif
Other DBs
NCBI-ProteinID:
CBJ21552
UniProt:
D3H6R0
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All DBs
Position
276080..277402
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AA seq
440 aa
AA seq
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MKEFENNQWIAHYRTDQPHFGLERMVELLALRGNPHLKLKVIHIGGTNGKGSTIAFLKNL
LEKLGLRVGVFSSPYLIHYTDQISINGKSIPETRLETLMADYQSLLEGGAAASLQGTTEF
EIITAIAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILTGITTIGLDHVALLGDTLGAI
AEQKAGIIKQGIPLVTGHIAPEALAVIDCIAEGKDAPRLAYGKDYQVSHQESVVTGEVFD
YASAVRQGRFQTGLLGLYQIENAGMAIALLDTFCQEDGRELPANTLLAQALEETSWPGRL
EVVSRDPLMILDGAHNPHAIKALIATLQERFADYRKEILFTCIKTKALEDMLDLLGAMPD
TELTLTHFDDSRATDESVLKEAAKSRNLSYQDWQNFLEQKLTDKKEEKQTVRIVTGSLYF
LSQVRAYLMERKNENGYTKD
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaaagaatttgaaaacaatcagtggattgcccactatcggacggatcaaccgcatttt
ggcttggaacgaatggtggaactgttagctttgcgtggcaatccccatctcaaactcaag
gtcatccatatcggagggactaacggcaagggttcgaccattgcttttttgaaaaatctg
ctagaaaagctagggctgagagttggcgtgtttagctcgccctatctcattcattacaca
gatcagattagcatcaatgggaaatccattcccgagactagactcgaaactctcatggca
gactatcagtctttgctggaggggggagcagccgctagtttacagggcacaaccgagttt
gagattatcacagccatagcctatgactactttgcttcagagcaagtagatgtggctatc
atggaagtcggcatgggtggtcttttagatagtaccaatgtctgtcagcccattttgaca
ggaattacgactattggattggaccatgtagcccttttaggtgacaccttgggagccata
gcagagcagaaggcaggtattatcaaacaaggaattccattggtgacaggtcacatcgct
ccagaagccttggctgtgattgactgcattgcggaagggaaagatgcgccgagacttgcc
tacgggaaagattatcaggtcagtcaccaagagagtgtggtgacaggcgaggtctttgat
tatgcaagtgctgtcaggcaagggcgcttccagacaggtttacttggtttgtaccagata
gagaatgctgggatggccatagctttacttgatactttttgtcaagaagatggtcgagag
ttaccagctaatactttgcttgctcaagccctggaagaaacaagttggccagggcgtttg
gaagttgtgtcaagagaccccctgatgattttggatggggcccacaatcctcatgctatc
aaggctttaatagcaaccttgcaagaacgctttgcggattatcgtaaggaaatcctcttt
acctgcatcaaaaccaaggccttggaagatatgttggacttgctgggggccatgccagat
accgagcttaccctgacacattttgacgatagtcgggcgactgatgaaagcgtgctgaaa
gaggcagctaagtctagaaatctcagctaccaagattggcagaattttctagagcagaaa
ttgacagataaaaaagaagagaaacaaacagttaggattgtcacaggttccttgtatttc
ttgagccaagtgagagcctatctgatggagaggaaaaacgagaatggatacacaaaagat
tga
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