Sinorhizobium medicae: Smed_3240
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Entry
Smed_3240 CDS
T00555
Name
(GenBank) FolC bifunctional protein
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
smd
Sinorhizobium medicae
Pathway
smd00790
Folate biosynthesis
smd01100
Metabolic pathways
smd01240
Biosynthesis of cofactors
Module
smd_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
smd00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
Smed_3240
Enzymes [BR:
smd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
Smed_3240
6.3.2.17 tetrahydrofolate synthase
Smed_3240
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
BPD_transp_1_N
Motif
Other DBs
NCBI-ProteinID:
ABR62064
UniProt:
A6UEI4
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All DBs
Position
3414978..3416321
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AA seq
447 aa
AA seq
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MTATEVSEAAREIEKLLALHPKGFDLSLDRITRLLAALGNPQERLPPVIHVAGTNGKGSV
TAFCRSILEAAGLSVHVHTSPHLVNWHERYRLGVKDGKGALVSDPVLADAVRRVAEANGG
QKITVFEILTAVTFLLFAEHPADVAIIEVGLGGRYDATNVIARPAVSVIMPISLDHQAYL
GDRVELIAAEKAGIMKRGCPVVIGHQEEESAREVLIETAERLGCPTSVYGQDFMAHEEFG
RLIFQDENGLADLPLPRLPGRHQYANAAAAIRAVRAAGFDVPEPAIEKGLAGVEWPGRLQ
RLAGGRLSHFGPPGAEIWIDGGHNPGAGHVIAEAMATFEERDPRPLFLIIGMINTKDPIG
YFKAFLDLTEQVFTVPVHGSDAGLDPLALAADAAAAGLEANAASSVAEALGQIAELTDED
PVPPRVLIGGSLYLVGDVLAENGTPPR
NT seq
1344 nt
NT seq
+upstream
nt +downstream
nt
atgacggcgactgaggtcagcgaggcggcgcgggagatcgagaagcttctcgccctccac
ccgaaaggattcgacctctcgctcgacaggatcacgcggctgctcgccgctctcggcaat
ccacaagagcgcctgcccccggtcattcacgtcgcggggacgaacggcaagggctcggtc
acggccttctgccgttcgattctggaggctgcgggcctgagcgtccacgttcacacatcg
ccgcatctggtgaactggcacgagcgctaccgcctgggcgtcaaggacggcaagggcgct
ttggtcagcgaccctgtgctcgcagacgccgtgcggcgcgtcgcagaagcgaatggcggc
cagaagattaccgtctttgaaatcctgaccgccgtcactttccttcttttcgcggagcat
ccggccgatgtcgcgatcatagaagtcggtctcggcggccgatatgacgcgaccaatgtc
atcgctcggccggcggtctcggtgatcatgcccatttcgctcgaccatcaggcatatctc
ggcgatcgagtcgaactgatcgctgcggaaaaggccgggatcatgaagcgcggctgcccg
gtggtgatcggccatcaggaggaagaaagcgcacgcgaggtgctgatcgagacagccgaa
cgccttggctgccccacatccgtgtacgggcaggatttcatggcgcatgaggagtttggc
aggctgatcttccaggacgagaacggcctggccgatttgccgttgccccgcctgccgggc
aggcatcaatatgccaatgccgctgctgccatccgcgccgtacgggcagccggcttcgat
gttccggagccagcgatcgagaagggactggccggcgtcgagtggccagggcggctgcag
cgtctcgcgggcggcaggctttcgcatttcggcccgccgggcgccgagatctggatcgac
ggcgggcataatcccggtgccggccatgtcatcgccgaggcgatggccaccttcgaggag
cgtgacccgaggccgctctttctgatcatcgggatgatcaacaccaaggatccgatcggt
tatttcaaggcttttctcgacctgaccgaacaggtcttcaccgtgcctgttcacggttcc
gatgcagggctggaccctctggcgctcgctgcggacgcggccgctgccgggctcgaggcc
aatgccgcttcctcggtcgccgaagcgctgggccagatcgccgagctcacggacgaggac
ccggtgccaccgcgtgtgctgatcggcggatcgctctatctggtgggcgacgtgctggcg
gagaacggtacgccgccgcgatag
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