Streptococcus mutans GS-5 (serotype c): SMUGS5_00540
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Entry
SMUGS5_00540 CDS
T02185
Name
(GenBank) pyruvate dehydrogenase E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
smut
Streptococcus mutans GS-5 (serotype c)
Pathway
smut00010
Glycolysis / Gluconeogenesis
smut00020
Citrate cycle (TCA cycle)
smut00620
Pyruvate metabolism
smut00785
Lipoic acid metabolism
smut01100
Metabolic pathways
smut01110
Biosynthesis of secondary metabolites
smut01120
Microbial metabolism in diverse environments
smut01200
Carbon metabolism
smut01210
2-Oxocarboxylic acid metabolism
Module
smut_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
smut00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SMUGS5_00540
00020 Citrate cycle (TCA cycle)
SMUGS5_00540
00620 Pyruvate metabolism
SMUGS5_00540
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SMUGS5_00540
Enzymes [BR:
smut01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SMUGS5_00540
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
DUF1194
Motif
Other DBs
NCBI-ProteinID:
AFM80644
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All DBs
Position
126340..127302
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AA seq
320 aa
AA seq
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MLSKKQYLDMFLKMQRIRDVDTKLNKLVRRGFVQGMTHFSVGEEAASVGAIQGLTDQDII
FSNHRGHGQTIAKGIDIPAMFAELAGKATGSSKGRGGSMHLANLEKGNYGTNGIVGGGYA
LAVGAALTQQYDNTGNIVVAFSGDSATNEGSFHESVNLAAVWNLPVIFFIINNRYGISTD
INYSTKISHLYLRADAYGIPGHYVEDGNDVIAVYEKMQEVIDYVRSGNGPALVEVESYRW
FGHSTADAGAYRTKEEVDAWKAKDPLKKYRTYLTENKIATDEELDMIEKEVAQEIEDAVK
FAQDSPEPELSVAFEDVWVD
NT seq
963 nt
NT seq
+upstream
nt +downstream
nt
atgttatctaaaaaacaatatttggatatgtttttaaaaatgcagcgtatccgtgatgtc
gatacaaaactcaataaattagttcgtcgtggtttcgtacaaggtatgacacacttttca
gtaggagaagaggcggcttcggttggtgcgattcaaggcttgactgatcaggatattatc
ttttcaaatcaccgtggacatggtcaaaccattgcaaaagggattgacattcctgctatg
tttgcagaattagccggtaaggcaacgggttcttcaaaaggtcgtggtggttctatgcac
ttggcaaatcttgaaaaagggaactatgggaccaatggtattgttggcgggggttatgcc
ttagcagtcggtgctgctttgacacagcaatatgacaatacgggaaatattgttgtcgcc
ttttcaggagactcggcaactaatgaaggttctttccatgagtctgttaatttggcagct
gtctggaatttaccggttatcttctttattattaataatcgttatggtatctcaacagat
atcaattattctactaagatttcacatctttatttacgtgctgatgcttatggtattcct
ggacattatgttgaagatggtaatgatgtcattgcagtttatgaaaaaatgcaggaagtc
attgattatgtgcgttcaggaaatgggccagctcttgttgaagtggaatcttatcgttgg
ttcggacattctactgctgatgcaggagcttaccgtacaaaagaagaagtagatgcttgg
aaagctaaagatcctctcaagaaataccgcacttatctaacggaaaataagattgcaaca
gatgaggaacttgatatgattgaaaaagaagtcgcacaggaaattgaggatgcagtgaaa
tttgcccaagatagccctgaaccagagctttctgtagcttttgaagatgtttgggtagat
tag
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