Streptococcus pneumoniae 670-6B (serotype 6B): SP670_0272
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Entry
SP670_0272 CDS
T01308
Name
(GenBank) dihydrofolate:folylpolyglutamate synthetase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
snb
Streptococcus pneumoniae 670-6B (serotype 6B)
Pathway
snb00790
Folate biosynthesis
snb01100
Metabolic pathways
snb01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
snb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SP670_0272
Enzymes [BR:
snb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SP670_0272
6.3.2.17 tetrahydrofolate synthase
SP670_0272
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ADM90349
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Position
239708..240958
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AA seq
416 aa
AA seq
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MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTGTNGKGSTIAFMRELFM
GHGKKVATFTSPHIVSINDRICINGQPIADADFIRLTDQVKEMEKTLLQTPAQLSFFELL
TLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVITSIGLDHQETLGDSLEAIAEQ
KAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQAGQDFLMLNGDFSSSLLNLSQLN
IGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVRKALEQTHWAGRLERIRPQIYLDGA
HNLPALTRLVEFIKEKEQEGYRPQILFGALKRKDYQGMLGYLTEKLPQVELKVTGFDYQG
ALDERDVTGYDIVSSYREFISDFEERADAQDLLFVTGSLYFISEVRGYLLDREQIN
NT seq
1251 nt
NT seq
+upstream
nt +downstream
nt
atgtttgaagtagaagaatggctccatagtcggattggtttgaattttcgatcaggtttg
ggccgaatgcagcaagcggtggatttgttaggaaatcctgagcagtcttaccctattatc
cacgtaacagggactaatgggaaaggatctaccattgcttttatgagggaattatttatg
gggcatggcaaaaaagttgcgacctttacctcccctcatatcgtctctatcaatgaccga
atctgcattaatgggcaacctatagcagacgcagactttatccgtttgactgatcaggtc
aaggagatggagaaaacgcttctgcaaactcctgcccagttgtccttttttgaattgctg
accttagttgcttttctttattttagggagcaagaggtggatttggttttattagaagtg
ggaattggtggcttacttgacacgaccaatgtggtaactggagagcttgctgtcatcacc
tccattgggcttgaccatcaagaaaccttgggtgatagtctagaagcaattgcagagcag
aaagctggtattttcaaggctggtaagaaggcagtgattgcgaaattgcctccagaagct
aggcttgtctgtcagaaaaaagccgaatctttagctgttaacctttatcaggcaggtcaa
gattttttaatgctgaatggtgatttttcaagctctttactaaatctttcacagctgaac
ataggcttagaaggagtctatcagcaggagaatgcagccttggcgttgcaaacttttctt
ctttttatgggagaaggaaaggaagctgttgatgaacaggctgtaagaaaggccttggaa
cagacccattgggctggtcgcttggagcgtattcgcccacagatttacttggatggtgct
cataacctccctgccttgactcgcttggttgagtttatcaaagaaaaagagcaggaaggt
tatcgtcctcaaatcctttttggagccttgaaacggaaggattatcaagggatgttaggt
tacctgactgaaaaattgcctcaggtggaactcaaggtgaccggctttgactatcagggg
gctttggacgaaagggatgtgacaggttacgatatagtttcttcttaccgagaatttatc
agcgattttgaagaaagagcagatgctcaggatttgctgttcgttacagggtctctctat
tttatctcagaagtacggggctacctgctggaccgtgagcagataaattga
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