Streptococcus pneumoniae ATCC 700669 (serotype 23F ST81 lineage): SPN23F02790
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Entry
SPN23F02790 CDS
T00843
Symbol
folC
Name
(GenBank) putative putative folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sne
Streptococcus pneumoniae ATCC 700669 (serotype 23F ST81 lineage)
Pathway
sne00790
Folate biosynthesis
sne01100
Metabolic pathways
sne01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sne00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SPN23F02790 (folC)
Enzymes [BR:
sne01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SPN23F02790 (folC)
6.3.2.17 tetrahydrofolate synthase
SPN23F02790 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
CAR68137
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Position
265787..267109
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AA seq
440 aa
AA seq
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MKEIQNNQWIANYRTDQPHFGLERMEELLALRGNPHLKLKVIHIGGTNGKGSTIAFLKKM
LEKLGLRVGVFSSPYLIHYTDQISINGESIPEARLEALMGDYQSLLEGESATNLQGTTEF
EIITAIAYDYFASEQIDVAIMEVGMGGLLDSTNVCQPILTGITTIGLDHVALLGDTLEAI
AEQKAGIIKQGIPLVTGRIAPEALAVIDRIAEGKDAPRLAYGIDYQVSHQKSVVTGEVFD
YTSVVRQGRFQTGLLGLHQIENAGMAIALLDTFCQEDGRELASNHLLAQALEETSWPGRL
EIVSRDPLMILDGAHNSHAIKALLATLQERFADYRKEILFTCIKTKALEDMLDLLEQIPD
TELTLTHFDDSRATDENVLKEAAKSRNLSYQGWQDFLEQKLTDKKEEKQTVRIVTGSLYF
LSQVRAYLMERNNENGYTKD
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaaagaaattcaaaacaatcagtggattgctaactaccggacggaccaaccgcatttt
ggcttggaacgaatggaggaactattagctttgcgtggcaatccccatctcaaactcaag
gtcatccatatcggagggaccaatggcaagggttcgaccattgcttttttgaaaaagatg
ctagaaaagctagggctgagagttggggtgttcagctcgccctatctcattcattataca
gaccagattagcatcaatggggaatctatcccagaggctagactagaagccctcatggga
gactatcagtctttgctggaaggggaatcggctaccaatttgcaggggacaactgagttt
gaaataattacagctatagcctatgattactttgcctcagagcaaatagatgtggctatc
atggaagtgggtatgggtggactcttggatagtaccaatgtctgccagcccattttaaca
ggcattacgactattggactggaccatgtagccctacttggtgacaccttggaagccata
gcagagcagaaagctggtattatcaaacaaggaattcccttggtgacaggtcgtatcgct
ccagaagccttggctgtgattgaccgcattgcggaagggaaagatgcgccgagacttgcc
tacgggatagattatcaggtcagccatcaaaagagtgtggttacaggcgaagtctttgac
tatacaagtgttgtcagacaaggtcgcttccagactggcctgcttggtttgcaccagata
gagaatgctgggatggccatagctttacttgatactttttgtcaagaagatggtcgagaa
ctagcaagcaatcacttgcttgctcaagctttggaagaaacaagttggccagggcgtttg
gaaatcgtgtcaagagatcccttgatgattttggatggagcccacaattcccatgctatc
aaggctttattagcaaccttgcaagaacgctttgcggattatcgtaaggaaatcctcttt
acttgcatcaaaaccaaggccttggaggatatgttggatttgttggagcaaatcccagat
accgagcttaccctgacacattttgacgatagtcgggcgactgatgaaaacgtgctgaaa
gaggcagccaagtctagaaatctcagctatcagggttggcaggattttctagagcagaaa
ttgacagataaaaaagaagagaaacaaacagttaggattgtcacaggttccttgtatttc
ttgagccaagtgagagcctatctgatggagaggaacaacgaaaatggatacacaaaagat
tga
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