Streptomyces nigrescens: HEK616_23420
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Entry
HEK616_23420 CDS
T08756
Symbol
oplA
Name
(GenBank) 5-oxoprolinase
KO
K01469
5-oxoprolinase (ATP-hydrolysing) [EC:
3.5.2.9
]
Organism
snig
Streptomyces nigrescens
Pathway
snig00480
Glutathione metabolism
snig01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
snig00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00480 Glutathione metabolism
HEK616_23420 (oplA)
Enzymes [BR:
snig01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.2 In cyclic amides
3.5.2.9 5-oxoprolinase (ATP-hydrolysing)
HEK616_23420 (oplA)
BRITE hierarchy
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Gene cluster
GFIT
Motif
Pfam:
Hydantoinase_B
Hydantoinase_A
Hydant_A_N
Hydant_A_C
Motif
Other DBs
NCBI-ProteinID:
BDM68855
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Position
2622116..2625724
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AA seq
1202 aa
AA seq
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MTTGRWEFWIDRGGTFTDVVGRRPDGRLVTGKLLSHHPERYRDAAVAGIRMMLGLGPDEP
VPADRVSVVKMGTTVATNALLERKGEPTVLLITEGFRDALRIAYQNRPRIFDRRIVLPEA
LYDRVIEVPERIGAHGDVVRPLEAGRVREALREARADGLSSAAVVLMHGYRHPDHEQAVA
ELAREAGFPQVSCSHEVSPLMKLVPRGDTTVVDAYLSPILARYVDEIAAQLPGIRLMFMQ
SNGGLRQAAHFRGKDAVLSGPAGGVVGMVRTAAEAGDGHDRVIGFDMGGTSTDVSHYAGE
FERVFGNEVAGVRMRAPMMNIHTVAAGGGSVLHFDGRRYRVGPDSAGADPGPACYRRGGP
LTVTDANVMLGRIQPAHFPAVFGPDGDRPLDDEAVRERFTELAARAAAETGDDRGPEEVA
AGFLDIAVLNMANAVKKISVQRGHDVTRYALTSFGGAGGQHACAVADALGINTVLVPPLA
GVLSAYGIGVADATAMREQAVEAEFSDPAALDHVHEVCAALADQTRRELLDDGVPDASIT
TRARVLVRYAGTDSPLGVPLGDAAAMAEEFVRAHRERYAFTMDKPLVAEAVSVEARGESG
GARGYEARTGGREGELAPAATVRMYAGGRWRDTGLYRRTELRPGDVLTGPAIVAEADATT
VVDPDWQAEMGDRGHLLLTRTRPRGDRVAVGTEADPVMLEVFNSLFMAIAEQMGVRLENT
AHSVNIKERLDFSCALFDAEGNLIANAPHIPVHLGSMGESIKEVLRRRRGDLRPGDVYAI
NDPYHGGTHLPDVTVVTPVFDADGDDLLFLVASRGHHAEIGGITPGSMPAFSTTIQEEGI
LFDNWLLVRDGTLRERETRELLTSGPYPSRSPDANLADLRAQIAANEKGIQELRRMTDQF
GLDVVRAYMGHVQDNAEESVRRIIARLSDGSYRYETDSGAEIRVALTVDRDARSAVLDFA
GTSPQQPGNANAPTSVVMAAVLYVFRTLVAEDIPLNSGCLKPVEVRIPEGSMLAPVFPAA
TVAGNVETSQAVTGALYAALGIQAEGSGTMNNLTFGNDRVQYYETVASGSGAGDGFHGAD
AVQTHMTNSRLTDPEVLEWRYPVRVDAFAIRDGSGGRGRWHGGCGVERRLRFLEPVTLAL
LTHHRRVPPYGMAGGAPGALGANLIERADGSCEELRGCDAADAGVDDVLVLRTPGGGGYG
EP
NT seq
3609 nt
NT seq
+upstream
nt +downstream
nt
atgacgaccggacgctgggagttctggatcgaccggggtggcaccttcacggacgtcgtc
ggcagacgcccggacgggcggctggtcaccgggaaactgctctcgcaccaccccgagcgc
taccgggacgccgcggtggccggcatccggatgatgctcggcctgggcccggacgaaccg
gtgcccgccgaccgggtctccgtcgtcaagatgggcaccaccgtcgccaccaacgccctc
ctggagcgcaagggcgaaccgaccgtgctgctcatcaccgagggcttccgcgacgcgctg
cggatcgcctaccagaaccgcccgcggatcttcgaccgccggatcgttctgcccgaggcg
ctctacgaccgggtgatcgaggtgccggagcggatcggggcgcacggcgacgtggtccgg
ccgctggaggccggccgggtccgcgaggcgctgcgggaggcccgcgccgacgggctgagc
agcgccgccgtcgtcctcatgcacggctaccgccaccccgaccacgagcaggccgtcgcc
gagctggcccgggaggccggcttcccccaggtcagctgctcgcacgaggtcagcccgctg
atgaagctggtgccgcgcggcgacaccaccgtcgtcgacgcctacctctcgccgatcctg
gcccgttacgtcgacgagatcgccgcccagctcccgggcatccggctgatgttcatgcag
tccaacggcgggctgcgccaggccgcgcacttccgcgggaaggacgcggtgctctccggc
cccgcgggcggcgtggtcggcatggtccgtacggccgccgaggccggtgacggccacgac
cgggtgatcggcttcgacatgggcggcacctccaccgacgtgtcgcactacgccggtgag
ttcgagcgggtcttcggcaacgaggtcgccggcgtccggatgcgcgccccgatgatgaac
atccacaccgtcgcggccggcggcggctcggtgctgcacttcgacgggcgccgctaccgg
gtcggccccgactcggccggcgccgacccgggaccggcctgctaccggcgcggcggcccg
ctgaccgtcaccgacgccaatgtgatgctcggccgcatccagccggcccacttccccgcg
gtgttcggccccgacggcgaccggccgctggacgacgaggcggtccgggagcgcttcacg
gaactggccgcccgggccgccgccgagaccggggacgaccgcggccccgaggaggtcgcc
gccgggttcctggacatcgccgtgctcaacatggccaacgcggtcaagaagatctccgtc
cagcgcggccacgacgtcacccgctacgccctcaccagtttcggcggcgccggcggccag
cacgcctgcgcggtcgccgacgccctgggcatcaacacggtcctcgtcccgccgctggcc
ggcgtgctctcggcgtacggcatcggggtcgcggacgccaccgcgatgcgcgaacaggcc
gtcgaggcggagttctccgaccccgccgcgctcgaccacgtccacgaggtgtgcgccgcg
ctcgccgaccagacccgccgagaactcctcgacgacggggtgccggacgcgtcgatcacc
acccgtgcccgggtgctggtccgctacgccgggaccgactcccccctcggcgtcccgctc
ggcgacgccgcggcgatggccgaggagttcgtccgggcgcaccgcgagcggtacgccttc
accatggacaagccgctggtcgccgaggcggtgtcggtcgaggcgcgcggggagtccggc
ggcgcccgcggctacgaggcacgaaccggcggccgggaaggggagttggcgcccgcggcg
acggtgcggatgtacgccggcggacgctggcgggacaccggcctgtaccggcggaccgaa
ctgcggcccggtgacgtcctcaccggcccggcgatcgtcgccgaggccgacgccaccacc
gtcgtcgaccccgactggcaggcggagatgggcgaccgcgggcacctgctgctgacccgt
acccgcccgcgcggcgaccgggtcgcggtcggcaccgaggccgacccggtgatgctggag
gtcttcaacagcctcttcatggccatcgccgagcagatgggcgtccggctggagaacacc
gcgcactccgtcaacatcaaggagcggctggacttctcctgcgcgctgttcgacgccgag
ggcaatctgatcgccaacgccccgcacatccccgtgcatctgggctcgatgggggagtcc
atcaaggaggtgctccggcggcgccggggcgatctgcgaccgggcgacgtctacgcgatc
aacgacccgtaccacggcggcacccacctgccggacgtcacggtcgtcacgcccgtcttc
gacgccgacggcgacgacctgctgttcctggtggcctcccgcggccaccacgccgagatc
ggcggcatcacccccggttcgatgccggcgttcagcaccaccatccaggaggagggcatc
ctcttcgacaactggctgctggtgcgggacgggacgctgcgcgagcgcgagacccgtgag
ctgctcacctccggcccgtacccgtcccgttcgccggacgccaacctcgccgatctgcgc
gcccagatcgccgcgaacgagaagggcatccaggaactccgcaggatgaccgaccagttc
ggcctggacgtcgtacgggcctacatgggtcacgtccaggacaacgccgaggaatcggtc
cgccggatcatcgcccggctgtcggacggcagctaccgctacgagaccgacagcggcgcg
gagatccgggtcgcgctgaccgtcgaccgggacgcccgcagcgccgtgctggacttcgcc
ggcacctcgccccagcagcccggcaacgccaacgcgcccacctcggtggtgatggccgcg
gtgctgtacgtcttccgcaccctggtcgccgaggacatcccgctcaacagcggctgcctc
aagcccgtcgaggtccgcatccccgagggctcgatgctggcccccgtcttcccggcggcc
accgtcgcgggcaacgtggagacctcccaggcggtcaccggcgcgctctacgccgcgctg
ggcatccaggccgagggctccggcacgatgaacaacctcaccttcggcaacgaccgggtg
cagtactacgagaccgtggccagcggttcgggcgccggcgacggcttccacggcgcggac
gccgtgcagacccacatgaccaactcccggctgaccgaccccgaggtcctggagtggcgc
tacccggtccgggtcgacgccttcgcgatccgcgacggcagcggcggccgcggacgctgg
cacggcggctgcggtgtcgagcgccggctgcgcttcctggaaccggtcaccctcgccctg
ctcacccaccaccgccgcgtcccgccgtacggcatggcgggcggcgccccgggcgcgctg
ggcgccaacctcatcgaacgtgccgacggcagctgcgaggagctccggggctgcgacgcg
gcggacgccggggtggacgacgtactggtgctgcggacgcccggtggcgggggctacggg
gagccgtga
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