Streptococcus pneumoniae 70585 (serotype 5): SP70585_1216
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Entry
SP70585_1216 CDS
T00872
Name
(GenBank) pyruvate dehydrogenase E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
snm
Streptococcus pneumoniae 70585 (serotype 5)
Pathway
snm00010
Glycolysis / Gluconeogenesis
snm00020
Citrate cycle (TCA cycle)
snm00620
Pyruvate metabolism
snm00785
Lipoic acid metabolism
snm01100
Metabolic pathways
snm01110
Biosynthesis of secondary metabolites
snm01120
Microbial metabolism in diverse environments
snm01200
Carbon metabolism
snm01210
2-Oxocarboxylic acid metabolism
Module
snm_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
snm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SP70585_1216
00020 Citrate cycle (TCA cycle)
SP70585_1216
00620 Pyruvate metabolism
SP70585_1216
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SP70585_1216
Enzymes [BR:
snm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SP70585_1216
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
ACO16565
UniProt:
C1C7D5
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All DBs
Position
complement(1127878..1128846)
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AA seq
322 aa
AA seq
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MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVGEEAANVGAMLALNPDD
LITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMHIADLDAGNLGANGIVGGG
MGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNMASIWNLPVIFYCINNGYGIS
ADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEGFQKAVDHVRSGNGPVLIESVTY
RWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLIENNIASAEELEKIQAQVKEAVEAS
VKFAEESPFPPLESAFEDIYTD
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atgtcaactttagataaaaatcttttgctagaaatgttccgtaagatggaagaaatccgt
cgcatggacttaaaaattgcacaattagtaaagaaagggaaagtgccaggaatgacgcac
ttttctgttggtgaagaggcagctaacgtgggggctatgttagctctcaatccagatgat
ctgattacctcaaaccaccgtggacacgggcaagctattgctaaagggattgacctcaac
ggaatgatggctgaaatccttggtaaatacactggaacctgtaaagggaaaggtggatct
atgcatatcgctgaccttgatgctgggaaccttggtgccaatggtatcgtaggtggtggt
atggggatcgctgtcggtgcagccctcagtcagcaaatgcaaaataccggtaaaatcgtt
gtttgcttctttggagatggtgcgaccaatgaaggtgttttccacgaagcagtgaacatg
gcttctatctggaacctgccagtcattttctattgcattaacaacggttacggtatctct
gcggatatcaagaaaatgaccaatatagaacatatccatcaacgtagcgccgcttatgga
attcctggaatgttcatcgaagacggtaacaatgtcatcgatgtctatgaaggatttcag
aaagctgtagaccatgttcgcagtggcaatggtccagtcttgattgaaagtgtaacttat
cgctggcttggtcactcatcatctgaccctggtaaatatcgtacgcgtgaagaagtggaa
ttgtggaaacaaaaagatccaatcgaaaacctccgcaattaccttattgaaaataacatt
gcaagtgccgaagaattggaaaaaatccaagcgcaagtaaaggaagcagtagaagcttct
gttaaatttgcagaggaaagcccattcccaccgcttgaatcagcctttgaagatatttac
acagactaa
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