Sphaerotilus sulfidivorans: EWH46_05905
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Entry
EWH46_05905 CDS
T06182
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
snn
Sphaerotilus sulfidivorans
Pathway
snn00790
Folate biosynthesis
snn01100
Metabolic pathways
snn01240
Biosynthesis of cofactors
Module
snn_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
snn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
EWH46_05905 (folC)
Enzymes [BR:
snn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
EWH46_05905 (folC)
6.3.2.17 tetrahydrofolate synthase
EWH46_05905 (folC)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QEN00361
UniProt:
A0A5C1PYP1
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Position
1278358..1279704
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AA seq
448 aa
AA seq
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MMTLSDWLAHCERLHPSTIELGLERVQRVREQLGLRFEVPVFTVAGTNGKGSTCAMLESI
LMQAGYRTAVYGSPHLVRFEERMRLNGEVVAAELLLPHFEAVEAARLATGQSLTYFEFTT
LAILRAMSVQSLDAVILEVGLGGRLDAVNIIDTDCAVITSIDLDHMDWLGPDREAIGREK
AGIMRPGRPVVVSDPVPPQSVVDHAEALGADLWRFGRDFNYAGDRQQWGWSGRGRRWNAL
GYPALRGANQLINAAGVLAALEAMRSRLPVPAQAIRNGLALVELPGRFQVVPGQPTLVLD
VAHNPHAAAVLAQNLDQMGYFPRTHAVLGAMADKDLAGLVAPLLPLVDTWHLCALDIGRA
ASPEQLRAAIETAVAARPADAAPLPPQRIVLHADPVAALGQSLKSADPTDRIVVFGSFHT
VGGVLQKGLPRLGAAHVGPAAGAPTKAA
NT seq
1347 nt
NT seq
+upstream
nt +downstream
nt
atgatgaccctttccgactggctcgcccactgcgagcggctgcatccgtcgacgatcgag
ctgggcctggagcgtgtgcagcgcgtgcgcgagcagcttggcctgcgcttcgaggtgccg
gtgttcacggtggccgggaccaacggcaagggctcgacctgcgcgatgctcgaatccatc
ctgatgcaggccggctaccgcactgcggtctacggctcgccgcatctggtgcgcttcgag
gagcgcatgcgcctgaacggcgaggtggtggccgctgagctgctgctgccgcatttcgag
gcggtcgaggcggcgcgcctggccaccgggcagtcgctgacctatttcgagttcaccacg
ctggccatcctgcgcgcgatgagcgtgcagtcgctggatgcggtgatcctggaggtgggc
ctgggcgggcggctcgacgcggtcaacatcatcgacaccgactgcgcggtcatcaccagc
atcgatctcgaccacatggactggctggggccggaccgcgaggcgatcggccgcgagaag
gccggcatcatgcgcccgggccgtccggtggtggtctccgacccggtgccgccgcagagc
gtggtcgatcacgccgaggcgctcggcgccgacctctggcgcttcggccgcgacttcaac
tatgccggcgaccgccagcagtggggctggagcgggcgcgggcggcgctggaacgcgctg
ggctatccggcgctgcgcggcgccaaccagctgatcaatgccgcgggcgtgctggcagcg
ctggaggcgatgcgctcgcgcctgccggtgccggcgcaggccatccgcaacggcctggcg
ctggtggagctgcccgggcgcttccaggtggtgccgggccagccgacgctggtgctcgac
gtggcccacaacccgcatgcggcggcggtgctggcgcagaacctcgatcagatgggctac
ttcccgcgcacccacgcggtgctgggcgcgatggccgacaaggatctggccgggctggtc
gcgccgctgctgccgctggtcgacacctggcatctgtgcgcgctcgacatcggccgtgcc
gcctcgcccgagcagctgcgcgccgcgatcgagacggcggtcgcggcccggccggcggat
gccgcaccgctgccgccgcagcgcatcgtgctgcacgccgatccggtcgccgccctggga
caatccctgaagtcggccgaccccactgatagaatcgtcgtcttcggatcgttccacacc
gtcggtggagtgctgcagaagggactgccgagactgggtgcggcccatgtcgggccggct
gcgggtgccccgaccaaagcggcctga
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