Streptococcus pneumoniae AP200 (serotype 11A): SPAP_1050
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Entry
SPAP_1050 CDS
T01309
Name
(GenBank) Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
snp
Streptococcus pneumoniae AP200 (serotype 11A)
Pathway
snp00010
Glycolysis / Gluconeogenesis
snp00020
Citrate cycle (TCA cycle)
snp00620
Pyruvate metabolism
snp00785
Lipoic acid metabolism
snp01100
Metabolic pathways
snp01110
Biosynthesis of secondary metabolites
snp01120
Microbial metabolism in diverse environments
snp01200
Carbon metabolism
snp01210
2-Oxocarboxylic acid metabolism
Module
snp_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
snp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SPAP_1050
00020 Citrate cycle (TCA cycle)
SPAP_1050
00620 Pyruvate metabolism
SPAP_1050
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SPAP_1050
Enzymes [BR:
snp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SPAP_1050
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
ADM84639
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Position
987637..988605
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AA seq
322 aa
AA seq
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MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVGEEAANVGAMLAFNPDD
LITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMHIADLDAGNLGANGIVGGG
MGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNMASIWNLPVIFYCINNGYGIS
ADIKKMTNVEHIHQRSAAYGIPGMFIEDGNNVIDVYEGFQKAVDHVRSGNGPVLIESVTY
RWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLIENNIASAEELEEIQAQVKEAVEAS
VKFAEESPFPPLESAFEDIYAD
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atgtcaactttagataaaaatcttttgctagaaatgttccgtaagatggaagaaatccgt
cgcatggacttaaaaattgcacaattagtaaagaaagggaaagtgccaggaatgacgcac
ttttctgttggtgaagaggcagctaacgtgggggctatgttagctttcaatccagatgat
ctgattacctcaaaccaccgtggacacgggcaagctattgctaaagggattgacctcaac
ggaatgatggctgaaatccttggtaaatacactggaacctgtaaagggaaaggtggatct
atgcatatcgctgaccttgatgctgggaaccttggtgccaatggtatcgtaggtggtggt
atggggatcgctgtcggtgcagccctcagtcagcaaatgcaaaataccggtaaaatcgtt
gtctgcttctttggagatggtgcgaccaatgaaggtgttttccacgaagcagtgaacatg
gcttctatctggaacctgccagtcattttctattgcattaacaacggttacggtatctct
gcggatatcaagaaaatgaccaatgtagaacatatccatcaacgtagcgccgcttatgga
attcctggaatgttcatcgaagacggtaacaatgtcatcgatgtctatgaaggatttcag
aaagctgtagaccatgttcgcagtggcaatggtccagtcttgattgaaagtgtaacttat
cgctggcttggtcactcatcatctgaccctggtaaatatcgtacgcgtgaagaagtggaa
ttgtggaaacaaaaagatccaatcgaaaacctccgcaattaccttattgaaaataacatt
gcaagtgccgaagaattggaagaaatccaagcgcaagtaaaggaagcagtagaagcttct
gttaaatttgcagaggaaagcccattcccaccgcttgaatcagcctttgaagatatttac
gcagactaa
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