Streptococcus pyogenes NZ131 (serotype M49): Spy49_0807
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Entry
Spy49_0807 CDS
T00780
Symbol
acoA
Name
(GenBank) Pyruvate dehydrogenase E1 component alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
soz
Streptococcus pyogenes NZ131 (serotype M49)
Pathway
soz00010
Glycolysis / Gluconeogenesis
soz00020
Citrate cycle (TCA cycle)
soz00620
Pyruvate metabolism
soz00785
Lipoic acid metabolism
soz01100
Metabolic pathways
soz01110
Biosynthesis of secondary metabolites
soz01120
Microbial metabolism in diverse environments
soz01200
Carbon metabolism
soz01210
2-Oxocarboxylic acid metabolism
Module
soz_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
soz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Spy49_0807 (acoA)
00020 Citrate cycle (TCA cycle)
Spy49_0807 (acoA)
00620 Pyruvate metabolism
Spy49_0807 (acoA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Spy49_0807 (acoA)
Enzymes [BR:
soz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Spy49_0807 (acoA)
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
ACI61117
UniProt:
A0A0H3BYN2
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All DBs
Position
801026..802006
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AA seq
326 aa
AA seq
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MEAEMVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVGEEAANVGAVAHL
SYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMHLADFEKGNYGTNGI
VGGGYALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNMAATWKLPVIFFIINNR
YGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYETMGKAVEHVRGGNGPAIVE
VESYRWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLTSEGIATDDELDAIQAQVKKE
IDDAYEFAQNSPDPELSVAFEDVWVD
NT seq
981 nt
NT seq
+upstream
nt +downstream
nt
atggaggccgaaatggtaacagtttctaaagaacaacatttggatatgttccttaaaatg
gaacgtattcgtgaatttgattcacgtattaataaactcgtccgtcgtggatttgtacaa
gggatgactcacttctcagttggtgaagaagcagccaatgttggagcggtggctcacttg
tcttacgatgacattattttttcaaatcaccgtggacatggacaatcaatcgctaaagac
atggaccttaataaaatgatggctgagcttgctggtaaagcaactggtgtttctaaaggg
cgtggtggctcaatgcacttggctgattttgaaaaaggaaactatggtaccaatggtatc
gttggtggtggttacgctcttgcagttggtgctgccctcactcaacaatacaaaggaact
aacaatatagctgttgctttctcaggtgatggcgctactaacgaaggatcattccacgag
tctgttaatatggctgcaacatggaaacttcctgttattttcttcatcatcaacaaccgt
tatggaatttcaatgagcatcaataatgcaacaaatacaccacacttatacacacgtgca
gaagcttacggaattcctggtttctactgtgaagatggcaatgacgtgatggctgtctat
gaaacaatgggcaaagccgttgaacatgttcgtggtggaaatggtccagctattgttgag
gtagaatcataccgttggtttggtcactcgactgcagatgctggtaaataccgtactaaa
gaagaagtggatgagtggaaagaaaaagatccaatgatcaaatatcgtacttatctgaca
agcgaaggcattgccactgatgacgaattggatgctattcaagcacaagtcaaaaaagaa
attgacgatgcttatgaatttgcacaaaacagtccagatccagaactttcagtagccttc
gaagacgtttgggttgactaa
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