Streptococcus pyogenes NZ131 (serotype M49): Spy49_0851
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Entry
Spy49_0851 CDS
T00780
Symbol
folC1
Name
(GenBank) Dihydrofolate synthase / Folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
soz
Streptococcus pyogenes NZ131 (serotype M49)
Pathway
soz00790
Folate biosynthesis
soz01100
Metabolic pathways
soz01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
soz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
Spy49_0851 (folC1)
Enzymes [BR:
soz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
Spy49_0851 (folC1)
6.3.2.17 tetrahydrofolate synthase
Spy49_0851 (folC1)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ACI61159
UniProt:
A0A0H3BY72
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Position
850952..852229
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AA seq
425 aa
AA seq
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MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHIVGTNGKGSTVNHLQHI
FTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAANRIRPLTERLVQETDFGEVTE
FEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAMVVVCPSIGLDHQAILGETYA
DIAAQKAGVLEGGETLVFAVENPSAREVFLTKAEQVGASIWEWQEQFQMAENASGYRFTS
PLGVISDIHIAMPGHHQVSNAALAIMTCLTLKDRYPRLTSDHIREGLANSLWLGRTELLA
PNLMIDGAHNNESVAALVAVLKNNYNDKKLHILFGAIDTKPIADMLVALEQIGDLQVTGF
HYPNAYPLEKYPERFGRVADFKDFLALRKHAKADDFFVITGSLYFISEIRRYWKKHIEKN
VLLTH
NT seq
1278 nt
NT seq
+upstream
nt +downstream
nt
atgacttatgaagagactctagaatggattcatgatcacttagttttcggcatcaagcca
ggcttaaaacgtatgctttgggttcttggacagttaggaaatccccaaaaaaatgtcaag
ggagtgcatatcgttggaactaacggaaaaggttccacggtcaatcatttacaacacatt
tttacgacagctggttatgaagtggggacctttacctctccttatattatggatttcaaa
gaacgtattagcataaatggtcgaatgatttcagaaaaagatttggttattgctgctaat
cgtattcgtcctttgacagagcgtctagttcaagagactgattttggagaggtaactgaa
tttgaagtgattactttgatcatgttcctctattttggagacatgcatcctgtagatatt
gctattattgaagcaggccttggcggtctttatgattcgaccaatgtttttcaagcaatg
gttgtggtatgtccctcaattggtttagatcaccaagctattttgggagagacttacgct
gatattgccgcccaaaaagctggtgttttagaagggggcgagacccttgtttttgccgtt
gaaaacccgtcagctcgagaggtttttttaacaaaagctgagcaggttggtgcttcaatc
tgggaatggcaagagcagtttcaaatggctgagaacgcatctggctatcgttttactagt
cctttaggagttatttcagatattcacatcgctatgccaggacaccaccaagtgtctaat
gcagctttagctattatgacttgcttaaccttgaaagaccgctatcctaggctaacttca
gatcatataagggaaggtctggcaaatagtttgtggctaggccgtaccgaattattagca
ccaaatctaatgattgatggggctcataacaatgaaagcgttgctgctttggtagccgtc
ttaaaaaataactacaatgataaaaagcttcatattttgtttggtgcgatcgacaccaag
cctattgcggatatgttggttgctcttgagcaaataggtgacttgcaggttactggcttt
cattaccctaacgcctatccattggaaaaatacccagaacgttttggtagggttgctgat
ttcaaagatttcttggccctgcgtaagcatgctaaagcagatgactttttcgtgattaca
gggtcactatattttatttcagaaattagacggtattggaaaaaacatattgaaaaaaac
gttcttttaacccattaa
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