Streptococcus pyogenes MGAS10394 (serotype M6): M6_Spy1774
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Entry
M6_Spy1774 CDS
T00191
Name
(GenBank) Histidine ammonia-lyase
KO
K01745
histidine ammonia-lyase [EC:
4.3.1.3
]
Organism
spa
Streptococcus pyogenes MGAS10394 (serotype M6)
Pathway
spa00340
Histidine metabolism
spa01100
Metabolic pathways
Module
spa_M00045
Histidine degradation, histidine => N-formiminoglutamate => glutamate
Brite
KEGG Orthology (KO) [BR:
spa00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
M6_Spy1774
Enzymes [BR:
spa01000
]
4. Lyases
4.3 Carbon-nitrogen lyases
4.3.1 Ammonia-lyases
4.3.1.3 histidine ammonia-lyase
M6_Spy1774
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Gene cluster
GFIT
Motif
Pfam:
Lyase_aromatic
Motif
Other DBs
NCBI-ProteinID:
AAT87909
UniProt:
Q5X9K4
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All DBs
Position
1785743..1787227
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AA seq
494 aa
AA seq
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MFMVQLVSSLQVVCTTLCTDVATKWTKCPLRNKSRRKNMTRVINLDGESLTIEDVIAIAR
QGVACRIDDSAIEAVNASRKIVDDIVSEKRVVYGVTTGFGSLCNVSISPEDTVQLQENLI
RTHASGFGDPLPEDAVRAIMLIRINSLVKGYSGIRLSTIEKLLELLNKGVHPYIPEKGSL
GASGDLAPLAHMVLPMLGLGKAYYKGELLSGQEALDKAGIDKISLAAKEGLALINGTTVL
TAIGALATYDAIQLLKLSDLAGALSLEVHNGITSPFEENLHTIRPQSGQLATARNIRNLL
EGSQNTTVATQSRVQDPYTLRCLPQIHGASKDSIAYVKSKVDIEINSVTDNPIICKDGHV
ISGGNFHGEPMAQPFDFLGIAISEIGNVSERRVERLVNSQLSKLPSFLVKYPGLNSGFMI
TQYACASLASENKVLAHPASVDSIPSCENQEDFVSMAPPLLARPLKSLKILAASWLLKSW
QPAKLLISNLKIMN
NT seq
1485 nt
NT seq
+upstream
nt +downstream
nt
ttgtttatggtgcagttggtgtcatcattgcaagtagtgtgtactaccttatgcacggac
gtagccaccaaatggaccaaatgccccctaaggaacaaatctaggagaaaaaatatgaca
agagtgattaatttagatggcgaaagccttactatcgaagacgtgattgcgattgctcgc
caaggcgtagcctgtcgcattgatgatagtgctattgaagctgtgaatgcctctcgtaaa
attgttgatgacattgtcagtgaaaaacgggtggtttacggggtgaccactggttttgga
tccctttgtaacgtgagcatctcaccagaagatacagtccaactccaagaaaatttgatt
cgtacccatgctagtggatttggtgacccattgccagaagatgccgtgagagctatcatg
ctgatccgtatcaactctctcgtcaaagggtattctggtattcgtctatccaccattgaa
aaactgttggaactgctcaataaaggggttcatccttacattcctgaaaaagggtctcta
ggggcttcaggagatttggcaccgcttgctcacatggtgcttcctatgcttggtctaggg
aaagcttactacaaaggagagcttctttctggtcaagaagctcttgataaagctggtatt
gacaagatttctttagccgctaaagaaggactcgcccttatcaacggaacaactgttctc
actgcaatcggtgcccttgcaacctatgacgccattcaattattgaaactgtcagaccta
gctggtgccctttcccttgaagtgcataacggaatcactagtccatttgaagaaaacctt
cacaccattcgcccacaaagcggccagttggcaacagcccgcaatatccgaaacctcctt
gaaggcagccaaaacacaaccgtggctactcaatctcgtgtgcaagacccttacaccttg
cgctgcctgcctcaaattcatggggctagcaaagacagtatcgcctatgtcaaatccaaa
gttgacattgaaatcaattctgtcacagataatccaattatctgtaaagatggccacgtt
atttcaggaggtaacttccacggagaaccaatggcacagccatttgacttcttaggcatt
gccatttctgaaattggaaatgtttctgaacgccgtgtggaacgtttggtcaatagccag
ctcagcaaactaccatccttccttgtcaaatacccaggtctcaattcaggctttatgatt
acccagtacgcctgtgcctctcttgcttctgaaaacaaggttttggcacatccagccagt
gtggattctatcccatcttgtgaaaaccaagaagattttgtcagcatggcaccaccgctg
ctcgcaaggcctttgaaatccttaaaaattctcgccgcatcgtggctactgaaatcatgg
cagcctgccaagctcttgatctcaaacctgaaaatcatgaactag
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