Streptomyces paludis: DVK44_16010
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Entry
DVK44_16010 CDS
T06964
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
spad
Streptomyces paludis
Pathway
spad00280
Valine, leucine and isoleucine degradation
spad00640
Propanoate metabolism
spad00785
Lipoic acid metabolism
spad01100
Metabolic pathways
spad01110
Biosynthesis of secondary metabolites
spad01210
2-Oxocarboxylic acid metabolism
Module
spad_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
DVK44_16010 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
DVK44_16010 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DVK44_16010 (pdhA)
Enzymes [BR:
spad01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
DVK44_16010 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
XFP_N
Motif
Other DBs
NCBI-ProteinID:
AXG78955
UniProt:
A0A345HQI1
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Position
3634565..3635755
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AA seq
396 aa
AA seq
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MKKSSTSVQEPPAAAAYRPTPPPAWRPRTDPAPLLPDPEPYRAIGTDAAADADPALLLRL
YTELVRGRRYNTQATALTKQGRLAVYPSSTGQEACEVAAALVLRERDWLFPSYRDTLACV
VRGLDPVQALTLLRGDWHSGYDPREHRVAPLSTPLATQLPHAVGLAHAARLKGDDVVALA
LVGDGGTSEGDFHEALNFAAVWRAPVVFLVQNNGFAISVPLAKQSAAPSLAHKAVGYGMP
GRLVDGNDALAVHTVLAEAMARARRGDGPTLVEAVTYRVDAHTNADDATRYRDAAEVETW
RAHDPVRLLERELLARGVLDEAGVARAAEAAETMAARLRDRMNAEPALDPMEIFAHIWAE
PTPQLREQAAQLRAELEAEASPDGGAGAGEGSGEAR
NT seq
1191 nt
NT seq
+upstream
nt +downstream
nt
gtgaagaaaagcagtacgtcggtccaggaaccacccgccgccgcggcctaccggcccacc
ccgcccccggcgtggcgcccgcgtaccgaccccgccccgctgctccccgaccccgagccg
taccgggcgatcggtacggacgccgcggcggacgccgatcccgcgttgctgctgcggctc
tacacggagctggtgcgcggccgcaggtacaacacgcaggcgacggcgctcaccaagcag
gggcggctcgcggtctatccgtcgagcaccggccaggaggcgtgcgaggtcgccgcggcg
ctggtcctgcgcgagcgggactggctcttccccagctaccgcgacaccctcgcgtgcgtg
gtgcgcgggctcgaccccgtacaggcgctgacgctgctgcgcggcgactggcactccggc
tacgacccgcgcgaacaccgcgtagccccgctctccacaccgctggccacccagctgccg
cacgcggtcggcctggcgcacgcggcccggctcaagggggacgatgtggtcgcgctggcc
ctggtgggggacggcggcacgagcgagggcgacttccacgaggcgctgaacttcgccgcc
gtctggcgcgcgccggtggtcttcctcgtccagaacaacggcttcgcgatctccgtaccg
ctcgccaagcagagcgcggcgccctccctggcccacaaggccgtcgggtacgggatgccg
ggccggctcgtggacgggaacgacgcgctcgcggtgcacacggtgctcgccgaggccatg
gcgcgggcccggcgcggcgacggcccgacgctcgtggaggccgtgacgtaccgcgtcgac
gcgcacacgaacgccgacgacgccacgcgctaccgggacgcggcggaggtcgagacctgg
cgggcgcacgacccggtccggctgctggagcgggagctgctggcccgcggcgtgctcgac
gaggcgggcgtcgcccgggcggcggaggcggccgagacgatggccgcgcggctgcgcgac
cggatgaacgccgagccggcgctcgacccgatggagatcttcgcgcacatctgggcggag
ccgacgccccagctgcgcgagcaggcggcgcagctccgcgcggagctggaagccgaggcg
tcccccgacggaggcgccggggccggggaagggtcgggtgaggcgcgatga
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