Sphingomonas alpina: H3Z74_10160
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Entry
H3Z74_10160 CDS
T07078
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
spap
Sphingomonas alpina
Pathway
spap00790
Folate biosynthesis
spap01100
Metabolic pathways
spap01240
Biosynthesis of cofactors
Module
spap_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
spap00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
H3Z74_10160
Enzymes [BR:
spap01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
H3Z74_10160
6.3.2.17 tetrahydrofolate synthase
H3Z74_10160
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QNQ11459
UniProt:
A0A7H0LP56
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Position
2212955..2214277
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AA seq
440 aa
AA seq
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MPDHATSASPAVQTQLDRLWSLSPGADILGLGRVTELLARIGNPQDRLPPVFHVAGTNGK
GSTCAFLRAAIEAAGRTAHVYTSPHLVRFNERIRIAGCLIEDDALANLLAEVLDHADGIG
ASFFEVTTAAAFLAFSRTPADACIVEVGLGGRLDATNVIASPAATGIAQLGVDHQFFLGN
TAEEIAGEKAGIAKAGVPLVTMRYPASVAQRVASVAHAAGAPVSAAGETWQFSADDRHLT
YKDTAGSIETPLPALAGPHQPENLALAIAMLRHQRQLRIPPKAYETAAGAARWPARMQRL
GQGPLTALLPEGSQLWLDGGHNPAAGIAVAAALREIVDAGSRIHLVLGMLANKDPEGLLA
PIREFVTSLHAVPVPDHDCHAPEDLAAIARAMTIPAFVAPDSVAALTAIARDSTAPPIIL
ILGSLYLAGEVLAENDEAPD
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgcccgaccatgccacctccgcctctccggcggtgcagactcagctcgaccgtctctgg
tcgctctcccccggcgccgatatcctcggcctggggcgggtcaccgaattgctcgcccgg
atcggcaacccgcaggataggctaccgccggtcttccatgtcgccggcaccaacggcaag
ggctcgacctgcgcctttctacgcgcggcgatcgaggccgcgggacggaccgcgcatgtc
tataccagcccgcatctcgtgcgcttcaacgagcggatccggatcgccggttgtttgatc
gaggacgatgcgctcgccaacttgctcgccgaagtgctcgatcatgccgacggcatcggc
gccagcttcttcgaggtcaccaccgccgccgcattcctcgccttttcacgcacccccgcc
gatgcctgcattgtcgaggtcggcctgggtgggcggctcgacgcgaccaatgtcatcgcc
agccccgccgcgaccggcatcgcgcagctcggggtcgatcatcaattctttctcggcaac
accgccgaggagattgccggcgagaaagcgggcatcgccaaggccggcgtgccgctcgtc
accatgcgctatccggcctccgttgcgcagcgtgtcgccagcgtcgcacatgccgctggc
gcgccggtttcggcggctggcgagacctggcaattcagcgctgacgaccggcatctgacg
tacaaggatacggccggcagcatcgagacgccgctccccgcgcttgccggtccgcatcaa
cctgaaaacctcgctctcgccattgccatgctgcggcaccagcgtcagctgagaatcccg
cccaaggcgtatgaaacggccgccggggcggcacgctggcccgcacgcatgcagcgcctc
ggccaaggcccgctcaccgcgcttctgccggaaggcagccagctctggctcgacggcggt
cataatccggcggcaggcatcgcggttgccgccgcgcttcgcgaaatcgtcgacgccggc
tcgcgcattcaccttgtcctcggcatgctcgccaacaaggatcccgaaggactgctcgcc
ccgatcagggagttcgtcacatcgctccatgcggtaccggtccctgaccatgattgccat
gcgccggaggatctcgccgccatcgcgcgtgccatgaccattcccgcctttgtcgcaccc
gattccgtcgcggcgctgaccgctatcgcacgcgattccaccgccccgccaatcattctg
atcctcggatcgctctatcttgccggtgaagtgctcgccgaaaacgacgaagcaccggat
tag
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