Streptomyces parvulus: Spa2297_11050
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Entry
Spa2297_11050 CDS
T04685
Name
(GenBank) dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
spav
Streptomyces parvulus
Pathway
spav00790
Folate biosynthesis
spav01100
Metabolic pathways
spav01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
spav00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
Spa2297_11050
Enzymes [BR:
spav01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
Spa2297_11050
6.3.2.17 tetrahydrofolate synthase
Spa2297_11050
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ANJ07492
UniProt:
A0A191UXU0
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Position
complement(2409228..2410742)
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AA seq
504 aa
AA seq
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MSDNPGDNDQPDPADPFEQIIAEETTRDPDLAVIEAGSRTLRTQGGPPQADVPGRPEDPE
VDEALREVEAELATRWGETKLEPSVARIAALMDVLGDPQRSYPSIHITGTNGKTSTARMI
EALLGAFELRTGRYTSPHVQSITERISLDGAAISAERFVETYRDIRPYVEMVDAQQEYRL
SFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVVTPIDLDHTDRLGETP
GEIATEKAGIVKQDATVILAQQPVDAAQVLLKKAVDVNATVAREGLEFGVVSRQVAVGGQ
LMTLRGLGGEYPELYLPLHGAHQAHNAAVALAAVEAFFGVGAQRPEPLDVDTVRKAFAAV
ASPGRMEVVRRSPTVVLDAAHNPAGARVTAEAVGEAFEFSRLIGVVGASGDKNVRGFLEA
FEPVFAEVVVTQNSSHRAMDADELAGIAVEVFGEDRVQVEPRLPDALEAAITLAEEEGEF
SGGGVLVTGSVITVGEARLLLGRG
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgacaaccccggcgacaacgaccagcccgaccccgctgaccccttcgagcagatc
atcgcggaggagaccacccgcgaccccgacctcgccgtcatcgaggccggcagccgcacc
ctgcgcacccagggcggccccccgcaggccgacgtccccgggcgccccgaggaccccgag
gtggacgaggccctgcgcgaggtcgaggcggagctggcgacccgctggggcgagaccaag
ctggagccgtccgtcgcccggatcgccgcgctgatggacgtgctgggcgacccgcagcgc
tcgtacccctccatccacatcacggggacgaacggcaagacctccaccgcccgcatgatc
gaggccctgctcggcgccttcgagctgcgcaccgggcgctacacctcgccgcacgtgcag
tcgatcaccgagcgcatcagcctggacggcgccgcgatctccgccgagcgcttcgtcgag
acgtaccgggacatcaggccgtacgtcgagatggtggacgcccagcaggagtaccggctg
tccttcttcgaggtgctgaccggcatggcctacgccgcgttcgccgacgcgcccgtggac
gtcgccgtcgtcgaggtcggcatgggcggctcctgggacgcgaccaacgtcatcgacggg
gacgtcgccgtcgtcacccccatcgacctggaccacaccgaccgcctgggcgagacgccc
ggcgagatcgcgaccgagaaggccggcatcgtcaagcaggacgcgaccgtcatcctggcc
cagcagccggtggacgccgcgcaggtgctgctgaagaaggccgtcgacgtcaacgccacc
gtcgcccgcgagggcctggagttcggcgtcgtctcccggcaggtcgccgtcggcggccag
ctgatgaccctgcgcggcctcggcggcgagtaccccgagctctacctgccgctgcacggc
gcccaccaggcgcacaacgccgccgtcgcgctggccgccgtggaggcgttcttcggcgtc
ggcgcgcagcggcccgagcccctggacgtcgacaccgtccgcaaggccttcgccgccgtc
gcctcgcccggacggatggaggtggtgcgccgctcgccgaccgtggtgctggacgccgcc
cacaatccggccggagcacgggtcaccgcggaggccgtcggggaggcgttcgagttcagc
cgcctcatcggcgtggtcggcgcgagcggcgacaagaacgtgcggggcttcctggaggcc
ttcgagccggtcttcgccgaggtcgtcgtcacccagaactccagccaccgcgcgatggac
gcggacgaactggccggcatcgccgtcgaggtgttcggcgaggaccgcgtccaggtcgag
ccccggctgccggacgccctggaggccgcgatcacgctggccgaggaggagggcgagttc
tcgggcggcggtgtgctcgtcaccggttccgtcatcaccgtcggcgaggcccgactgctc
ctggggaggggctga
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