Streptococcus pneumoniae D39 (virulent serotype 2): SPD_0052
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Entry
SPD_0052 CDS
T00413
Name
(GenBank) phosphoribosylformylglycinamidine synthase, putative
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
spd
Streptococcus pneumoniae D39 (virulent serotype 2)
Pathway
spd00230
Purine metabolism
spd01100
Metabolic pathways
spd01110
Biosynthesis of secondary metabolites
Module
spd_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spd00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SPD_0052
Enzymes [BR:
spd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
SPD_0052
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
GATase_3
DJ-1_PfpI
Motif
Other DBs
NCBI-ProteinID:
ABJ54799
UniProt:
A0A0H2ZNL6
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All DBs
Position
46496..50221
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AA seq
1241 aa
AA seq
DB search
MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDVFDLAEDLFAPAEKHIF
SEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQEALLLLGSSSDVTVNTAQL
YLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFSESDKTIPKLTFFESYTAEDF
ARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVLDTYWSDHCRHTTFETELKHIDF
SASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMATIFGRYERANGRLDDMEVSDEINA
CSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPFGGAATCIGGAIRDPLSGRSYVYQAMR
ISGAGDITAPISETRAGKLPQQVISKTAAHGYSSYGNQIGLATTYVREYFHPGFVAKRME
LGAVVGAAPKGNVVREKPEAGDVIILLGGKTGRDGVGGATGSSKVQTVESVETAGAEVQK
GNAIEERKIQRLFRNGNVTRLIKKSNDFGAGGVCVAIGELADGLEIDLNKVPLKYQGLNG
TEIAISESQERMAVVVRPEDVDTFVAECNKENIDAVVVATVTEKPNLVMHWNGETIVDLE
RRFLDINGVRVVVDAKVVDKDVKLPEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDC
SVGRSTVNHPLGGRYQLTPTEASVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYA
VIEATARLVAAGANWSKARFSYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGG
KDSMSGTFEELTVPPTLVAFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIK
KNFAQFEASQADHKVTSASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFV
FTSPEEIAGVEKIGQTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVP
AVASDVVIKAKEKVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKS
VETMVDNIDKTNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGIC
NGFQALVKSGLLPYGNFEDANNTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDI
HAIPVSHGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSK
NGQIIGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK
NT seq
3726 nt
NT seq
+upstream
nt +downstream
nt
atggataaacgtatttttgttgaaaaaaaggctgattttcaggtcaagtcagagagtttg
gttagagagctccagcacaacttgggactgtcaagcttgaaaagtattcgtattgtgcaa
gtatatgatgtatttgacttggctgaggacttgtttgcacctgcagagaagcacattttc
tctgagcagggaaccgaccatgttttagatgaagtatctgtgcaggcggatcttgctaac
tatgctttctttgccattgaaagtctgccagggcagtttgaccagcgtgcagcttcgtca
caggaagccttgcttttgttgggaagttcgagtgacgtgacagttaacacagcccaactt
tacttggtgaataaagatattgatgcgactgagttggaagctgtcaaaaactacctgctc
aatccagttgattctcgtttcaaggatatcacgacagggattgccaagcaggagttttca
gagtcagacaagaccattccaaaattgactttctttgaaagctatacagcagaagacttt
gctcgctacaaggccgagcaagggatggccatggaagtggatgatttgctctttatccaa
gactactttaagtcaatcgggcgcgtgccaactgagactgaactcaaggttttggacact
tactggtctgaccactgccgtcatacgacttttgagacagagttgaaacacatcgacttt
tcagcttctaaatttcaaaagcaattgcagtcaacctatgacaagtatattgccatgcgc
gaggagttaggtcggtctgaaaaaccacaaaccttgatggatatggcgactattttcggt
cgttatgagcgtgctaacggacgattggatgatatggaagtctctgacgaaatcaatgcc
tgctcagttgaaattgaagtggatgttgatggtgtcaaggaaccttggctcctcatgttt
aaaaatgaaacccacaaccatccaacagaaattgagccatttggtggagcggctacctgt
atcggtggagctattcgtgatccgttgtcaggccgttcctatgtttaccaagccatgcgt
atttcaggtgctggtgatattacagcaccgatttcggaaactcgtgctgggaaattgcca
caacaagtcatttctaaaacagcagctcatggttattcttcatatggtaaccagattggg
cttgccacaacctacgttcgtgaatacttccacccaggctttgtagctaaacgtatggaa
cttggtgccgttgttggtgcggctcccaagggcaatgttgtccgtgaaaaacctgaagca
ggtgatgtgatcatccttctcggaggtaaaacaggtcgtgatggtgtcggtggtgcgacg
ggctcttctaaggttcaaacagttgagtctgtagagactgctggtgctgaggttcaaaaa
ggaaatgccatcgaagaacgcaagattcagcgcctcttccgtaatggcaatgtcactcgt
ctgatcaagaagtccaatgactttggggcaggcggtgtctgtgtggctatcggtgaattg
gcagacggtcttgaaatcgacctcaacaaggtgcctcttaaataccagggcttgaatggt
acagaaattgccatctctgaatcacaagaacggatggcggttgtggttcgtcctgaagat
gtggataccttcgttgccgaatgtaacaaagaaaatattgatgctgttgtggtggcgaca
gtaactgaaaaaccaaatcttgtcatgcactggaatggtgagacaatcgttgacttggag
cgtcgtttccttgacatcaatggtgtgcgcgtggttgtcgatgccaaagttgtggacaag
gatgtcaaactcccagaagagcgtcaaacatctgctgaaacactggaatcagataccctt
acggttctatctgacctcaaccatgcaagtcaaaaaggattacagactatctttgactgc
tctgttggacgctcaacggttaatcacccacttggtggtcgttaccaactcacaccaact
gaggcatctgtgcagaaattgccagttcaacacggtgtgactcatactgcgtcggtcatt
gctcaaggtttcaacccatatgtagctgaatggtctccataccacggtgctgcttatgcg
gttatcgaagcaactgctcgtttggtggctgctggtgccaactggtccaaggctcgtttc
tcttaccaagaatatttcgagcgtatggacaagcaagcagagcgttttggtcagccagta
gccgctcttctaggctctattgaagctcagattcaacttggcttgccatctatcggtggt
aaggactccatgtctggtacctttgaagaattgaccgttccgccaaccttggttgccttt
ggggtgacgacggcagatagccgtaaggtgctctctccagaatttaaagctgttggggaa
aatatctactacatcccaggtcaagccctctctgcagagattgattttgacttgattaag
aaaaattttgctcagtttgaagcaagccaagctgaccataaagtgacatctgcatcagct
gtcaaatacggtggtgtagttgaaagtttggctcttgctacctttggaaactatattggt
gcagaggtgaccttgcctgaacttaaaacagctttgacagctcaattaggcggctttgtc
ttcacatctcctgaagaaattgctggagtagagaagattggacaaacgaaagcagacttt
acactgactgtcaacggtgtgaagctagatggacacaagcttgacagtgcatttcaaggg
acattggaagaagtttacccaacagaatttacccaagcgaaagaactagaagaagtacca
gctgtggcatcagatgttgtgattaaagccaaagaaaaggttgaaaaacctgtggtttac
atcccagtctttccaggaaccaactcagaatatgattcagctaaggccttcgaaaaagaa
ggtgcagaggtcaatttggtgccattcgtgaccttgaatgaagaagctattgtcaagtca
gttgaaactatggttgacaatatcgacaagactaatattctcttctttgctggtggattc
tcggctgcggatgaaccagatggttcagctaagtttatcgtcaatatcctgcttaatgaa
aaagtgcgtgtggctattgatagctttatcgcccgtggtggtttgattatcggtatttgt
aatggattccaagccttagtcaaatcgggtctcctaccctacggaaactttgaagatgct
aacaatactagcccaaccctcttctacaatgatgccaaccaacacgtggccaagatggtg
gaaactcgcattgccaataccaactcaccatggttggctggtgtgcaagtgggcgatatc
cacgctattcctgtttcgcacggtgaagggaagtttgtcgtgacggctgaggaatttgca
gagctccgtgacaatggacaaattttcagccaatacgttgactttaacggtaaaccaagt
atggattctaagtacaatccgaatggttctgtccatgccatcgaaggaattaccagcaag
aatggtcaaatcatcggtaagatgggccattcagaacgttatgaggacggtcttttccaa
aatatcccaggcaataaagaccagcacctgttcgcgtcagcggttaaacatttcactgga
aaataa
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