Streptococcus pneumoniae D39 (virulent serotype 2): SPD_1028
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Entry
SPD_1028 CDS
T00413
Symbol
acoA
Name
(GenBank) TPP-dependent acetoin dehydrogenase alpha-subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
spd
Streptococcus pneumoniae D39 (virulent serotype 2)
Pathway
spd00010
Glycolysis / Gluconeogenesis
spd00020
Citrate cycle (TCA cycle)
spd00620
Pyruvate metabolism
spd00785
Lipoic acid metabolism
spd01100
Metabolic pathways
spd01110
Biosynthesis of secondary metabolites
spd01120
Microbial metabolism in diverse environments
spd01200
Carbon metabolism
spd01210
2-Oxocarboxylic acid metabolism
Module
spd_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SPD_1028 (acoA)
00020 Citrate cycle (TCA cycle)
SPD_1028 (acoA)
00620 Pyruvate metabolism
SPD_1028 (acoA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SPD_1028 (acoA)
Enzymes [BR:
spd01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SPD_1028 (acoA)
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
ABJ54500
UniProt:
A0A0H2ZN82
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Position
complement(1053824..1054792)
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AA seq
322 aa
AA seq
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MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVGEEAANVGAMLALNPDD
LITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMHIADLDAGNLGANGIVGGG
MGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNMASIWNLPVIFYCINNGYGIS
ADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEGFQKAVDHVRSGNGPVLIESVTY
RWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLIENNIASAEELEKIQAQVKEAVEAS
VKFAEESPFPPLESAFEDIYTD
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atgtcaactttagataaaaatcttttgctagaaatgttccgtaagatggaagaaatccgt
cgcatggacttaaaaattgcacaattagtaaagaaagggaaagtgccaggaatgacgcac
ttttctgttggtgaagaggcagctaacgtgggggctatgttagctctcaatccagatgat
ctgattacctcaaaccaccgtggacacgggcaagctattgctaaagggattgacctcaac
ggaatgatggctgaaatccttggtaaatacactggaacctgtaaagggaaaggtggatct
atgcatatcgctgaccttgatgctgggaaccttggtgccaatggtatcgtaggtggtggt
atggggatcgctgtcggtgcagccctcagtcagcaaatgcaaaataccggtaaaatcgtt
gtttgcttctttggagatggtgcgaccaatgaaggtgttttccacgaagcagtgaacatg
gcttctatctggaacctgccagtcattttctattgcattaacaacggttacggtatctct
gcggatatcaagaaaatgaccaatatagaacatatccatcaacgtagcgccgcttatgga
attcctggaatgttcatcgaagacggtaacaatgtcatcgatgtctatgaaggatttcag
aaagctgtagaccatgttcgcagtggcaatggtccagtcttgattgaaagtgtaacttat
cgctggcttggtcactcatcatctgaccctggtaaatatcgtacgcgtgaagaagtggaa
ttgtggaaacaaaaagatccaatcgaaaacctccgcaattaccttattgaaaataacatt
gcaagtgccgaagaattggaaaaaatccaagcgcaagtaaaggaagcagtagaagcttct
gttaaatttgcagaggaaagcccattcccaccgcttgaatcagcctttgaagatatttac
acagactaa
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