Streptococcus pyogenes Manfredo (serotype M5): SpyM50968
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Entry
SpyM50968 CDS
T00497
Symbol
folC1
Name
(GenBank) putative folypolyglutamate synthase 1
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
spf
Streptococcus pyogenes Manfredo (serotype M5)
Pathway
spf00790
Folate biosynthesis
spf01100
Metabolic pathways
spf01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
spf00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SpyM50968 (folC1)
Enzymes [BR:
spf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SpyM50968 (folC1)
6.3.2.17 tetrahydrofolate synthase
SpyM50968 (folC1)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
CAM30295
LinkDB
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Position
complement(972508..973785)
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AA seq
425 aa
AA seq
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MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHIVGTNGKGSTVNHLQHI
FTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAANRIRPLTERLVRETDFGEVTE
FEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAMVVVCPSIGLDHQAILGETYA
DIAAQKAGVLEGGETLVFAVENPSAREVFLTKAEQVGASIWEWQEQFQMAENASGYRFTS
PLGVISDIHIAMPGHHQVSNAALAIMTCLTLKDRYPRLTSDHIREGLANSLWLGRTELLA
PNLMIDGAHNNESVAALVAVLKKNYNDKKLHILFGAIDTKPIADMLVALEQIGDLQVTGF
HYPNAYPLEKYPERFGRVADFKDFLALRKHAKADDFFVITGSLYFISEIRRYWKKHIEKS
VLLTH
NT seq
1278 nt
NT seq
+upstream
nt +downstream
nt
atgacttatgaagagactctagaatggattcatgatcacttagttttcggcatcaagcca
ggcttaaaacgtatgctttgggttcttggacagttaggaaatccccaaaaaaatgtcaag
ggagtgcatatcgttggaactaacggaaaaggttccacggttaatcatttacaacacatc
tttacgacagctggttatgaagtggggacctttacctctccttatattatggatttcaaa
gaacgtattagcataaatggtcgaatgatttcagaaaaagatttggttattgctgctaat
cgtattcgtcctttgacagagcgtctagttcgagagactgattttggagaggtaactgaa
tttgaagtgattactttgatcatgttcctctattttggtgatatgcatcctgtagatatt
gctattattgaagcaggccttggcggtctttatgattcgaccaatgtttttcaagcaatg
gttgtggtctgtccctcaattggtttagatcaccaagctattttgggagagacttacgct
gatattgccgcccaaaaagctggtgttttagaagggggcgagacccttgtttttgccgtt
gaaaacccgtcagctcgagaggtttttttaacaaaagctgagcaggttggtgcttcaatc
tgggaatggcaagagcagtttcaaatggctgagaacgcatctggctatcgttttactagt
cctttaggagttatttcagatattcacatcgctatgccaggacaccaccaagtgtctaat
gcagctttagctattatgacttgcttaaccttgaaagaccgctatcctaggctaacttca
gatcatataagggaaggtctagcaaatagtttgtggctaggccgtaccgaattattagca
ccaaatctaatgattgatggggctcataacaatgaaagcgttgctgctttggtagccgtc
ttaaaaaaaaactacaatgataaaaagcttcatattttgtttggtgcgatcgacaccaag
cctattgcagatatgttggttgctcttgagcaaataggtgacttgcaggttactggcttt
cattaccctaacgcctatccattggaaaaatacccagaacgttttggtagggttgctgat
ttcaaagatttcttggccctgcgtaagcatgctaaagcagatgactttttcgtgattaca
gggtcactatattttatttcagaaattagacggtattggaaaaaacatattgaaaaaagc
gttcttttaacccattaa
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