Streptococcus pyogenes Manfredo (serotype M5): SpyM51008
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Entry
SpyM51008 CDS
T00497
Symbol
pdhA
Name
(GenBank) putative pyruvate dehydrogenase E1 component,alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
spf
Streptococcus pyogenes Manfredo (serotype M5)
Pathway
spf00010
Glycolysis / Gluconeogenesis
spf00020
Citrate cycle (TCA cycle)
spf00620
Pyruvate metabolism
spf00785
Lipoic acid metabolism
spf01100
Metabolic pathways
spf01110
Biosynthesis of secondary metabolites
spf01120
Microbial metabolism in diverse environments
spf01200
Carbon metabolism
spf01210
2-Oxocarboxylic acid metabolism
Module
spf_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SpyM51008 (pdhA)
00020 Citrate cycle (TCA cycle)
SpyM51008 (pdhA)
00620 Pyruvate metabolism
SpyM51008 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SpyM51008 (pdhA)
Enzymes [BR:
spf01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SpyM51008 (pdhA)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
CAM30335
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All DBs
Position
complement(1015565..1016533)
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AA seq
322 aa
AA seq
DB search
MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVGEEAANVGAVAHLSYDD
IIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMHLADFEKGNYGTNGIVGGG
YALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNMAATWKLPVIFFIINNRYGIS
MSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYETMGKAVEHVRGGNGPAIVEVESY
RWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLTSEGIATDDELDAIQAQVKKEVDDA
YEFAQNSPDPELSVAFEDVWVD
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atggtaacagtttctaaagaacaacatttggatatgttccttaaaatggaacgtattcgt
gaatttgattcacgtattaataaactcgtccgtcgtggatttgtacaagggatgactcac
ttctcagttggtgaagaagcagccaatgttggagcggtggctcacttgtcttacgatgac
attattttttcaaatcaccgtggacatggacaatcaatcgctaaagacatggaccttaat
aaaatgatggctgagcttgctggtaaagcaactggtgtttctaaagggcgtggtggctca
atgcacttggctgattttgaaaaaggaaactatggtaccaatggtatcgttggtggtggt
tacgctcttgcagttggtgctgccctcactcaacaatacaaaggaactaacaatatagct
gttgctttctcaggtgatggcgctactaacgaaggatcattccacgagtctgttaatatg
gctgcaacatggaaacttcctgttattttcttcatcatcaacaaccgttatggaatctca
atgagcatcaataatgcaacaaatacaccacatttatacacacgtgcagaagcttacgga
attcctggtttctactgtgaagatggcaatgacgtgatggctgtctatgaaacaatgggc
aaagccgttgaacatgttcgtggtggaaatggcccagctattgttgaggtagaatcatac
cgttggtttggtcactcgactgcagatgctggtaaataccgtactaaagaagaagtggat
gagtggaaagaaaaagatccaatgatcaaatatcgtacttatctgacaagcgaaggcatt
gccactgatgacgaattggatgctattcaagcacaagtcaaaaaagaagttgacgatgct
tatgaatttgcacaaaacagtccagatccagaactttcagtagccttcgaagacgtttgg
gttgactaa
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