Streptococcus pyogenes Manfredo (serotype M5): SpyM51179
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Entry
SpyM51179 CDS
T00497
Symbol
folC2
Name
(GenBank) putative folypolyglutamate synthase 2
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
spf
Streptococcus pyogenes Manfredo (serotype M5)
Pathway
spf00790
Folate biosynthesis
spf01100
Metabolic pathways
spf01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
spf00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SpyM51179 (folC2)
Enzymes [BR:
spf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SpyM51179 (folC2)
6.3.2.17 tetrahydrofolate synthase
SpyM51179 (folC2)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
CAM30504
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Position
1177738..1179006
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AA seq
422 aa
AA seq
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MTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHVVGTNGKGSVTAYLQHI
LSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVSVIRPILTKMSLETNWDRPTE
FKLVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHALAVVCPSISFDHQERLGYSLA
EIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGSRLYQLGKDFLLNPSEKTISFQH
DNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFPKISPKTIQKGIETTTWPGRSEFIQ
PNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILFAGLKRKPLADLLAQLDTFEVSVTTFD
FPEANLLEDYPDKYPQVKDYRDWLQGSVTSDELFVVTGSLYFISEVRQYCLSNANIFKNI
FP
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atgactacctatgatagcatttcctggattcatacctttaaggctaatggtcgcaagacc
gatttggccagaatggcttggttacttgaggcactaggccggccacaagacaaattccct
gctattcacgttgttggaactaacggcaagggctctgtgacagcctacttacagcatatc
ctgtcaacttctggttatcaggtcggaacctttacatctccttttatcatctcttttcac
gatcggatttgccttaatggccagcccatttcagacctagaattggcgcaatgtgtgagc
gtgattagacccattctcactaaaatgtcccttgaaacaaattgggatagacctaccgag
tttaagttagtgactctcataatgttttgctactttgccaatcttaaacctgttgatatt
gccattattgaggcagggattggtgggaaaaccgacgcaaccaatgtttttcatgctctg
gccgtcgtatgcccttccattagttttgatcaccaagaacgtttaggttatagcctagca
gaaattgctcaccaaaaagcagaagttatcaaagctaaagaacccgttattatcggtcaa
cttgaacaggaggctagtcaagtctttcaacaagttacccaaaaagccggttcacgctta
tatcaattaggaaaagattttttgctcaatccttcagaaaagacgatttcctttcaacac
gataacttgaatttaaccaaactccgtctcaaactattaggtcaacatcaaaaagcgaat
gcctgtttagccattatgacagctcaattacttagaaaatcctttcctaaaatatctcca
aaaacgattcaaaaaggaattgagacaacaacttggcctggccggtccgaatttattcaa
cctaatcttctattagacggcgctcacaatccagattccattgctaaattaaagtctcta
ctgcaagaagaatttcccaaacgtcctattcatatcctctttgcaggtctcaaacgtaag
cctttagccgacttgctggctcaactagatacttttgaagtatctgtcacgacttttgat
ttccctgaagcaaatcttttagaggattatcctgataaatacccacaggtaaaagattac
agagactggttacaaggttccgtaacatctgatgaactctttgttgttacagggtcactt
tattttatctccgaggtaaggcaatattgtctgagcaacgcaaatatctttaaaaacata
ttcccctaa
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