Streptococcus pyogenes MGAS315 (serotype M3): SpyM3_0661
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Entry
SpyM3_0661 CDS
T00089
Symbol
acoA
Name
(GenBank) putative acetoin dehydrogenase (TPP-dependent) alpha chain
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
spg
Streptococcus pyogenes MGAS315 (serotype M3)
Pathway
spg00010
Glycolysis / Gluconeogenesis
spg00020
Citrate cycle (TCA cycle)
spg00620
Pyruvate metabolism
spg00785
Lipoic acid metabolism
spg01100
Metabolic pathways
spg01110
Biosynthesis of secondary metabolites
spg01120
Microbial metabolism in diverse environments
spg01200
Carbon metabolism
spg01210
2-Oxocarboxylic acid metabolism
Module
spg_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SpyM3_0661 (acoA)
00020 Citrate cycle (TCA cycle)
SpyM3_0661 (acoA)
00620 Pyruvate metabolism
SpyM3_0661 (acoA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SpyM3_0661 (acoA)
Enzymes [BR:
spg01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SpyM3_0661 (acoA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AAM79268
UniProt:
A0A0H2UU92
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All DBs
Position
723233..724201
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AA seq
322 aa
AA seq
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MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVGEEAANVGAVAHLSYDD
IIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMHLADFEKGNYGTNGIVGGG
YALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNMAATWKLPVIFFIINNRYGIS
MSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYETMGKAVEHVRGGNGPAIVEVESY
RWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLTSEGIATDDELDAIQAQVKKEVDDA
YEFAQNSPDPELSVAFEDVWVD
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atggtaacagtttctaaagaacaacatttagatatgttccttaaaatggaacgtattcgt
gaatttgattcacgtattaataaactcgtccgtcgtggatttgtacaagggatgactcac
ttctcagttggtgaagaagcagccaatgttggagcggtggctcacttgtcttacgatgac
attattttttcaaatcaccgtggacatggacaatcaatcgctaaagacatggaccttaat
aaaatgatggctgagcttgctggtaaagcaactggtgtttctaaagggcgtggtggctca
atgcacttggctgattttgaaaaaggaaactatggtaccaatggtatcgttggtggtggt
tacgctcttgcagttggtgctgccctcacccaacaatacaaaggaactaacaatatagct
gttgctttctcaggtgatggcgctactaacgaaggatcattccacgagtctgttaatatg
gctgcaacatggaaacttcctgttattttcttcatcatcaacaaccgttatggaatttca
atgagcatcaataatgcaacaaatacaccacacttatacacacgtgcagaagcttacgga
attcctggtttctactgtgaagatggcaatgacgtgatggctgtctatgaaacaatgggc
aaagccgttgaacatgttcgtggtggaaatggcccagctattgttgaggtagaatcatac
cgttggtttggtcactcgactgcagatgctggtaaataccgtactaaagaagaagtggat
gagtggaaagaaaaagatccaatgatcaaatatcgtacttatctgacaagcgaaggcatt
gccactgatgacgaattggatgctattcaagcacaagtcaaaaaagaagttgacgatgct
tatgaatttgcacaaaacagtccagatccagaactttcagtagccttcgaagacgtttgg
gttgactaa
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