Streptococcus pyogenes MGAS10270 (serotype M2): MGAS10270_Spy0870
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Entry
MGAS10270_Spy0870 CDS
T00355
Symbol
acoB
Name
(GenBank) Pyruvate dehydrogenase E1 component beta subunit
KO
K00162
pyruvate dehydrogenase E1 component subunit beta [EC:
1.2.4.1
]
Organism
sph
Streptococcus pyogenes MGAS10270 (serotype M2)
Pathway
sph00010
Glycolysis / Gluconeogenesis
sph00020
Citrate cycle (TCA cycle)
sph00620
Pyruvate metabolism
sph00785
Lipoic acid metabolism
sph01100
Metabolic pathways
sph01110
Biosynthesis of secondary metabolites
sph01120
Microbial metabolism in diverse environments
sph01200
Carbon metabolism
sph01210
2-Oxocarboxylic acid metabolism
Module
sph_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sph00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MGAS10270_Spy0870 (acoB)
00020 Citrate cycle (TCA cycle)
MGAS10270_Spy0870 (acoB)
00620 Pyruvate metabolism
MGAS10270_Spy0870 (acoB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MGAS10270_Spy0870 (acoB)
Enzymes [BR:
sph01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MGAS10270_Spy0870 (acoB)
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Gene cluster
GFIT
Motif
Pfam:
Transket_pyr
Transketolase_C
PFOR_II
Motif
Other DBs
NCBI-ProteinID:
ABF33935
UniProt:
Q1JH59
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All DBs
Position
825288..826289
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AA seq
333 aa
AA seq
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MMSETKLMALREAVNLAMTEEMRKDENIFLMGEDVGVYGGDFGTSVGMIEEFGPKRVKDT
PISEAAISGAAIGAAITGLRPIVDVTFMDFLTIMMDAIVNNGAKNNYMFGGGLITPVTFR
VASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGNANDAKGLLKSAIRDNNIVLFMEPKAL
YGKKEEVNQDPDFYIPLGKGDIKREGTDLTIVSYGRMLERVLQAAEEVAADGINVEVVDP
RTLIPLDKELIIESVKKTGKLMLVNDAYKTGGFIGEIATMITESEAFDYLDHPIVRLASE
DVPVPYARVLEQAILPDVEKIKAAIVKMANKGN
NT seq
1002 nt
NT seq
+upstream
nt +downstream
nt
atgatgtcagaaacaaaattaatggctttgcgtgaagcagtcaaccttgctatgactgag
gaaatgcgcaaggacgaaaacattttccttatgggtgaagacgtaggggtatacggagga
gactttggtacttctgttggaatgattgaagaatttggtcctaaacgtgttaaagatacc
ccaatttcagaagctgctatctctggtgcagctattggtgcagcgattacaggactacgt
ccaattgtcgacgttaccttcatggatttccttaccatcatgatggacgctatcgtgaat
aatggtgctaaaaataattacatgttcggtggaggccttattacccctgtaaccttccgt
gtggcatcaggttctggtattggttccgctgcgcaacactcacaatctcttgaagcatgg
ttgactcacattccaggaatcaaagttgttgctcctggtaatgccaacgatgctaaaggc
ttattaaaatcagctatccgtgataataacattgttcttttcatggaaccaaaagcgctt
tacggtaaaaaagaagaagttaaccaagatcctgacttctatatcccacttggcaaaggt
gacatcaaacgtgaaggaactgatttgacaattgtgtcatacggtcgtatgttggagcgt
gttcttcaagcggctgaagaagttgcagcggatggtattaacgttgaagttgttgaccca
cgtaccctcattccacttgataaagagttgattattgaatctgttaagaaaacaggtaaa
ttgatgcttgtcaacgatgcctacaagaccggtggattcattggggaaattgcaaccatg
attaccgaaagtgaagcctttgattaccttgatcatccaatcgttcgtcttgcaagtgaa
gatgttccagtaccttatgcacgtgtacttgaacaagcgatcttaccagacgttgagaaa
atcaaagctgccattgtgaaaatggcaaacaaaggcaactag
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