Streptomyces phaeolivaceus: F9278_12540
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Entry
F9278_12540 CDS
T07107
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sphv
Streptomyces phaeolivaceus
Pathway
sphv00010
Glycolysis / Gluconeogenesis
sphv00020
Citrate cycle (TCA cycle)
sphv00620
Pyruvate metabolism
sphv00785
Lipoic acid metabolism
sphv01100
Metabolic pathways
sphv01110
Biosynthesis of secondary metabolites
sphv01120
Microbial metabolism in diverse environments
sphv01200
Carbon metabolism
sphv01210
2-Oxocarboxylic acid metabolism
Module
sphv_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sphv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
F9278_12540 (aceE)
00020 Citrate cycle (TCA cycle)
F9278_12540 (aceE)
00620 Pyruvate metabolism
F9278_12540 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
F9278_12540 (aceE)
Enzymes [BR:
sphv01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
F9278_12540 (aceE)
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Ortholog
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QFQ96907
UniProt:
A0A5P8K2Q2
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Position
2689479..2692211
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AA seq
910 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIPTKAEPFFPGNEEIERKILNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGIYARAFMLDRLDERQLDAFRQ
EKSKAPYGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIFQARMNRYMEARGIADTSKSHVW
AFLGDGEMDEPESLGQLTLAAREGLDNLTFVVNCNLQRLDGPVRGNGKVIQELESVFRGA
GWNVIKLVWDRSWDPLLAQDRDGVLVNRMNTTPDGQYQTYATETGAYIRDHFFGDDQRLR
AMVEGMTDDQILHLGRGGHDHRKIYAAYKAAHEHKGQPTVILAKTVKGWTLGPNFEGRNA
THQMKKLTVADLKGFRDRLHLPISDKELESGAPPYYHPGRDSEEIQYMHDRRKGLGGYVP
TRVVRAKPLALPEEKTYASVKKGSGQQSIATTMAFVRLLKDLMRDKEIGKRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYEAVDRDLLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMSDQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAFGYEIAHIVKDGLRRMYGPDSEDVFYYLTVYNEPIQHPAEPA
DVDVEGILKGIHRYRAAEEGSIPAQIIASGVAVPWAVEAQRILAADWNVKADVWSATSWN
ELRREAVDVERHNLLHPEEEQQVPYVTRKLSAAEGPFVAVSDWMRSVPDQISRWVPGTYQ
SLGADGFGFADTRGAARRFFHIDAQSIVVAVLTELAREGKVDRSVLKQAIDRYQLLDVTA
ADPGAAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaatccgatcatcattggcggccttccgagtcaggtccct
gacttcgatcccgaggagacccaggagtggctcgactcgctcgacgccgcggtggacgag
cgcggccgtgagcgcgcgcgctatctgatgctccggctcatcgagcgggcccgcgagaag
cgcgtggccgtgccggagatgcgcagcacggactacgtcaacaccatcccgacgaaggcc
gagccgttcttcccgggcaacgaggagatcgagcggaagatcctcaacgcgacacggtgg
aacgccgccgtgatggtctcgcgcgcccagcggcccggtatcggcgtcggcggccacatc
gcgaccttcgcgtcctccgcctccctctacgacgtgggcttcaaccacttcttccgcggc
aaggacgagggcgacggcggcgaccagatcttcttccagggccacgcctcccccggtatc
tacgcccgcgcgttcatgctggaccggctcgacgagcggcagctggacgccttccgccag
gagaagtcgaaggcgccctacggcctgtccagctacccgcacccgcggctgatgccggac
ttctgggagttcccgacggtgtccatgggcctcggtccgctgggcgcgatcttccaggcg
cggatgaaccggtacatggaggcgcgtgggatcgcggacacctccaagtcccatgtctgg
gcgttcctcggcgacggcgagatggacgagccggagtcgctcggccagctcacgctcgcc
gcccgcgagggcctcgacaatctgaccttcgtcgtcaactgcaacctccagcgcctcgac
ggcccggtgcgcggcaacggcaaggtcatccaggagctggagtcggtcttccggggcgcc
ggctggaatgtgatcaagctggtctgggaccgctcctgggacccgctgctggcccaggac
cgcgacggtgtgctggtcaaccggatgaacaccactccggacggccagtaccagacgtac
gccacggagaccggcgcgtacatccgcgaccacttcttcggtgacgaccagcggctgcgc
gcgatggtcgagggcatgaccgacgaccagatcctgcacctgggtcgcggcggtcacgac
caccgcaagatctacgcggcgtacaaggcggcccatgagcacaagggccagccgacggtc
atcctggcgaagacggtcaagggctggacgctgggcccgaacttcgagggccgcaacgcc
acgcaccagatgaagaagctgacggtcgccgacctcaagggcttccgtgaccgcctccat
ctgcccatctccgacaaggagctggagtccggcgcgccgccgtactaccacccgggccgg
gactcggaggagatccagtacatgcacgaccgccgcaaggggctcggcgggtacgtcccg
acgcgtgtcgtgcgggcgaagccgctggccctgccggaggagaagacgtacgcgagtgtg
aagaaggggtccggtcagcagtcgatcgccaccaccatggcgttcgtccggctactgaag
gacctcatgcgggacaaggagatcggcaagcgtttcgtgctgatcgcgcccgacgagtac
cgcaccttcggcatggactcgttcttcccgagcgcgaagatctacaacccgctcggccag
cagtacgaggcggtcgaccgtgatctgctgctcgcgtacaaggagtcgccgacgggccag
atgctgcacgacggcatctcggaggcgggctgtacggcctcgctgatcgcggcgggttcg
gcgtacgccacgcacggcgagccgctcatcccggtgtacgtcttctactcgatgttcggt
ttccagcgcaccggtgaccagttctggcagatgtccgaccagctggcgcgtggtttcgtc
ctgggcgcgaccgccggccgtacgaccctgaccggtgagggcctccagcacgcggacgga
cactcgcagctgctcgcctcgacgaaccccggctgtgtcgcctacgacccggcgttcggg
tacgagatcgcgcacatcgtgaaggacggtctgcgccggatgtacggcccggacagcgag
gacgtcttctactacctcaccgtctacaacgagccgatccagcacccggccgagccggcg
gacgtggacgtcgagggcatcctcaagggcatccaccgctaccgggccgccgaggagggc
tcgatccccgcgcagatcatcgcctccggtgtggcggtgccgtgggcggtcgaggcgcag
cggatcctcgccgccgactggaacgtgaaggcggacgtctggtcggcgacctcctggaac
gagctgcgccgcgaggccgtcgacgtggagcggcacaatctgctgcaccccgaggaggag
cagcaggtcccgtatgtgacgcggaagctgagcgcggccgaggggccgttcgtggccgtc
tccgactggatgcggtcggtgccggaccagatctcgcggtgggtgccgggcacgtaccag
tcgctgggcgcggacggcttcggcttcgccgacacacggggcgcggcgcggcggttcttc
cacatcgacgcgcagtcgatcgtggtcgcggtgctgaccgagctggcccgtgagggcaag
gtcgaccgttcggtgctgaagcaggccatcgaccggtaccagctgctcgatgtgacggcg
gcggacccgggcgccgcgggaggcgatgcatag
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