Streptomyces phaeolivaceus: F9278_14250
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Entry
F9278_14250 CDS
T07107
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sphv
Streptomyces phaeolivaceus
Pathway
sphv00790
Folate biosynthesis
sphv01100
Metabolic pathways
sphv01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sphv00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
F9278_14250
Enzymes [BR:
sphv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
F9278_14250
6.3.2.17 tetrahydrofolate synthase
F9278_14250
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QFQ97181
UniProt:
A0A5P8K224
LinkDB
All DBs
Position
complement(3063566..3065074)
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AA seq
502 aa
AA seq
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MSERSESQPEPIDPFEEIIAAETDRDPDLAVIEAGSRTLRAQGGAPETDVPSRPTDPALD
KALRAVETDLATRWGETKLEPSVTRIAALMDVLGEPQRSYPSIHITGTNGKTSTARMIEA
LLGAFELRTGRYTSPHVQSITERISLDGAPISAERFIETYEDIKPYIEMVDSQQEYRLSF
FEVLTGMAYAAFADAPVDVAVVEVGMGGTWDATNVIDGDVAVVTPIDLDHTDRLGGTTAE
IAVEKAGIVKQDAAVILAQQPVDAAQVMLKKAVEVDATVAREGLEFGVVARQVAVGGQML
TLRGLGGEYPEVYLPLHGPYQAHNAAVALAAVEAFFGVGSQRPEPLDLDTVRKAFAAVSS
PGRLEVVRRSPTVVLDAAHNPAGARATAEAVGEAFDFSRLIGVVGASGDKNVRGLLEAFE
PIFAEVVITQNASHRAMDADELAGIAVEVFGEERVQVEPRLPDALEAAITLAEEEGEFAG
GGVLVTGSVITVGEARLLLGKG
NT seq
1509 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgaacgcagtgagtcgcagcccgagccgatcgacccgttcgaggagatcatcgcc
gcggagaccgacagggatcccgacctcgcggtgatcgaggccggcagccgtaccctgcgt
gcccagggcggcgcgccggagaccgacgtcccctcgcgccccaccgacccggccctcgac
aaggcgctgcgcgcggtcgagaccgacctcgcgacccgctggggcgagaccaagctggag
ccctcggtcacccggatcgccgcgctgatggacgtcctgggcgagccccagcgctcctac
ccctccatccacatcaccggcaccaacggcaagacctccaccgcccgcatgatcgaggcc
ctcctcggcgccttcgagctgcgcaccggccggtacacctccccgcacgtccagtcgatc
accgagcgcatcagcctggacggcgccccgatctccgccgagcgcttcatcgagacgtac
gaggacatcaagccgtacatcgagatggtcgactcccagcaggagtaccggctctccttc
ttcgaggtgctgaccggcatggcgtacgccgccttcgccgacgcccccgtggacgtggcc
gtcgtcgaggtgggcatgggcggcacctgggacgccaccaacgtcatcgacggggacgtg
gccgtcgtcacgcccatcgacctcgaccacaccgaccggctgggcgggacgaccgccgag
atcgccgtggagaaggccgggatcgtcaagcaggacgcggccgtgatcctggcgcagcag
ccggtggacgcggcgcaggtgatgctgaagaaggccgtggaggtggacgcgacggtggcc
cgggagggcctggagttcggtgtcgtcgcccggcaggtcgccgtcggcggacagatgctc
accctgcgcggcctgggcggcgagtaccccgaggtgtatctcccgctgcacggcccgtac
caggcgcacaacgcggccgtcgcccttgccgcggtcgaggcgttcttcggcgtcggctcg
cagcgcccggaaccgctggacctggacacggtccgcaaggccttcgcggcggtctcctca
ccgggccggctcgaagtcgtacgacggtccccgaccgtcgtcctcgacgccgcccacaac
ccggcgggcgcgcgggccaccgccgaggccgtcggagaggcgttcgacttcagccggctg
atcggtgtggtcggggccagtggcgacaagaacgtacggggtctcctggaggccttcgaa
ccgatcttcgccgaggtcgtgatcacccagaacgccagccatcgcgcgatggacgccgac
gagctggccgggatcgcggtcgaggtgttcggcgaggagcgggtgcaggtcgaaccgcgg
ctgccggacgccctggaggcggcgatcacgctcgccgaggaggagggcgagttcgcgggc
ggtggcgtcctcgtcaccggttccgtcatcaccgtcggcgaggcccggctgctgctgggg
aagggctga
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