Streptomyces phaeoluteigriseus: NFX46_34020
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Entry
NFX46_34020 CDS
T08568
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sphw
Streptomyces phaeoluteigriseus
Pathway
sphw00790
Folate biosynthesis
sphw01100
Metabolic pathways
sphw01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sphw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
NFX46_34020
Enzymes [BR:
sphw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
NFX46_34020
6.3.2.17 tetrahydrofolate synthase
NFX46_34020
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
USQ88329
LinkDB
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Position
complement(7687105..7688628)
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AA seq
507 aa
AA seq
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MSELPPNGNDDDQPDALDAFEEIIAAETDRDPDLAVIEAGSRTLRTLGGPAESGVPTRPA
DPEVDKALREVEAELATRWGETKLEPSVGRIAALMDLLGEPQRAYPSIHITGTNGKTSTA
RMIEALLGAFDLRTGRYTSPHVQSITERISLDGAPVPAERFIETYHDVKPYVEMVDAAQE
YRLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGSWDATNVIDGDVAVVTPIDLDHTDRLG
GTPAAIAVEKGGIIKSGATVILAQQPVDAAQVLLKKAVEVDATVAREGLEFGVVARQVAV
GGQLVTLRGVGGEYPEVYLPLHGPYQAHNAAVALAAVEAFFGVGAQRPEPLDIDTVRKAF
ASVSSPGRMEVVRRSPTVVLDAAHNPAGARATADAVGEAFDFSRLIGVVGASGDKNVRGL
LEAFEPIFAEVVVTQNSSHRAMGADELAAIAVEVFGEERVQVEPRLPDALEAAITLAEEE
GEFAGGGVLVTGSVITVGEARLLLGKG
NT seq
1524 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgagctcccccccaacggcaacgacgacgaccagcccgatgccctcgacgcgttc
gaggagatcatcgcggccgagaccgaccgcgaccccgacctcgcggtgatcgaggccggc
agccgcaccctgcgcaccctgggcggtccagcggagtccggcgtgcccacccggcccgcc
gaccccgaggtcgacaaggccctgcgcgaggtggaggcggagctggccacccgctggggc
gagaccaagctggagccgtccgtcggccggatcgccgcgctgatggacctcctgggcgag
ccgcagcgggcgtacccctcgatccacatcacggggacgaacggcaagacctccaccgcc
cgcatgatcgaggccctcctcggcgccttcgacctgcgcaccgggcgctacacctccccg
cacgtgcagtcgatcaccgagcgcatcagcctcgacggcgcgcccgtcccggccgagcgg
ttcatcgagacctaccacgacgtcaagccgtacgtggagatggtcgacgccgcccaggag
taccggctgtccttcttcgaggtgctcaccggcatggcgtacgccgccttcgccgacgcc
cccgtggacgtggccgtcgtggaagtgggcatgggcggctcctgggacgccaccaacgtg
atcgacggggacgtcgccgtcgtcacccccatcgacctcgaccacaccgaccggctcggc
gggacgcccgccgcgatcgccgtggagaagggcgggatcatcaagtcgggcgcgaccgtg
atcctcgcccagcagcccgtcgacgcggcgcaggtcctgctgaagaaggccgtcgaggtg
gacgccacggtggcgcgcgagggcctggagttcggggtcgtcgcccggcaggtcgcggtc
ggcggacagctcgtcaccctgcgcggcgtcggcggcgagtaccccgaggtgtacctcccg
ctgcacggcccctaccaggcgcacaacgcggccgtcgcgctcgccgccgtcgaggcgttc
ttcggcgtgggcgcccagcggcccgagccgctggacatcgacacggtccgcaaggccttc
gcgtccgtgtcgtcgcctggccgcatggaggtcgtccggcggtccccgaccgtcgtgctc
gacgccgcccacaacccggccggcgcccgcgccaccgccgacgcggtcggcgaggccttc
gacttcagccggctgatcggcgtggtcggggccagcggcgacaagaacgtgcgagggctg
ctggaggccttcgaaccgatcttcgccgaggtcgtcgtcacccagaacagcagccaccgc
gccatgggcgcggacgagctggccgcgatcgccgtcgaggtgttcggcgaggagcgcgtc
caggtcgagccgcggctgcccgacgccctggaggcggcgatcacgctcgccgaggaggag
ggcgagttcgccggcggcggcgtcctggtcaccggttccgtcatcaccgtcggggaagcc
cggctgctcctggggaagggctga
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