Streptococcus pyogenes MGAS10750 (serotype M4): MGAS10750_Spy0716
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Entry
MGAS10750_Spy0716 CDS
T00356
Symbol
folC2
Name
(GenBank) Folylpolyglutamate synthase / Dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
spi
Streptococcus pyogenes MGAS10750 (serotype M4)
Pathway
spi00790
Folate biosynthesis
spi01100
Metabolic pathways
spi01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
spi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
MGAS10750_Spy0716 (folC2)
Enzymes [BR:
spi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
MGAS10750_Spy0716 (folC2)
6.3.2.17 tetrahydrofolate synthase
MGAS10750_Spy0716 (folC2)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ABF37666
UniProt:
Q1J7A8
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All DBs
Position
complement(691812..693104)
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AA seq
430 aa
AA seq
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MLEGQEIVMTTYDSISWIHSFKANGRKTDLARMAWLLEALGRPQDKFPAIHVVGTNGKGS
VTAYLQHILSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVSVIRPILTKMSLE
TNWDRPTEFELVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHALAVVCPSISFDHQ
ERLGYSLAEIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGSRLYQLGKDFLLNPS
EKTISFQHDNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFPKISPKTIQKGIETTTW
PGRSEFIQPNLLLDGAHNPDSIAKLKSLMQEEFPKRPIHILFAGLKRKPLADLLAQLDTF
EVSVTTFDFPEANLLEDYPDKYPQVKDYRDWLQGSVTSDELFVVTGSLYFISKVRQYCLS
NANIFKNIFP
NT seq
1293 nt
NT seq
+upstream
nt +downstream
nt
ttgttagaaggacaagaaatagtaatgactacctatgatagcatttcctggattcatagc
tttaaggctaatggtcgcaagaccgatttggccagaatggcttggttacttgaggcacta
ggccggccacaagacaaattccctgctattcacgttgttggaactaacggcaagggctct
gtgacagcctacttacagcatatcctgtcaacttctggttatcaggtcggaacctttaca
tctccttttatcatctcttttcacgatcggatctgccttaatggccagcccatttcagac
ctagaattggcgcaatgtgtgagcgtgattagacccattctcactaaaatgtcccttgaa
acaaattgggatagacctaccgagtttgagttagtgactctcataatgttttgctacttt
gccaatcttaaacctgttgatattgccattattgaggcagggattggtgggaaaaccgac
gcaaccaatgtctttcatgctctggccgtcgtatgcccttccattagttttgatcaccaa
gaacgtttaggttatagcctagcagaaattgctcaccaaaaagcagaagttatcaaagct
aaagaacccgttattatcggtcaacttgaacaggaggctagtcaagtctttcaacaagtt
acccaaaaagccggttcacgcttatatcaattaggaaaagattttttgctcaatccttca
gaaaagacgatttcctttcaacacgataacttgaatttaaccaaactccgtctcaaacta
ttaggtcaacatcaaaaagcgaatgcctgtttagccattatgacagctcaattacttaga
aaatcctttcctaaaatatctccaaaaacgattcaaaaaggaattgagacaacaacttgg
cctggccggtccgaatttattcaacctaatcttctattagacggcgctcacaatccagat
tccattgctaaattaaagtctctaatgcaagaagaatttcccaaacgtcctattcatatc
ctctttgcaggtctcaaacgtaagcctttagccgacttgctggctcaactagatactttt
gaagtatctgtcacgacttttgatttccctgaagcaaatcttttagaggattatcctgat
aaatacccacaggtaaaagattacagagactggttacaaggttccgtaacatctgatgaa
ctctttgttgttacagggtcactttattttatctccaaggtaaggcaatattgtctgagc
aacgcaaatatctttaaaaacatattcccctaa
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