Streptomyces platensis: CP981_01325
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Entry
CP981_01325 CDS
T07341
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
spla
Streptomyces platensis
Pathway
spla00010
Glycolysis / Gluconeogenesis
spla00020
Citrate cycle (TCA cycle)
spla00620
Pyruvate metabolism
spla00785
Lipoic acid metabolism
spla01100
Metabolic pathways
spla01110
Biosynthesis of secondary metabolites
spla01120
Microbial metabolism in diverse environments
spla01200
Carbon metabolism
spla01210
2-Oxocarboxylic acid metabolism
Module
spla_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CP981_01325 (pdhA)
00020 Citrate cycle (TCA cycle)
CP981_01325 (pdhA)
00620 Pyruvate metabolism
CP981_01325 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP981_01325 (pdhA)
Enzymes [BR:
spla01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CP981_01325 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
QEV50495
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Position
290628..291764
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AA seq
378 aa
AA seq
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MSSSPTPGRDPAADTAGTARPAPASTVSDSEADVLRGYYRQMALIRAFELRAAEMYTRAK
IGGYCHLNLGEEATCVGLMAALRSTDYLFTTYREHGYALARGADPGRVMAELFGRTTGMS
GGRGGSMHLFDTELRLLGGYGIVGGQLPLATGAALAISYRGEPGSGSEAVMCLLGDGTTN
IGAFHEALNLAAVWHLPIVYVIVNNQLGMGTPVAAAAGEPELFRRGCAYRIPGTRVDGGD
VLAVRDAARMALEQARAEHHPRLLETVSYRLRGHSVVDPARYRTPEEAAQLREKDPVPAL
RIRLIEEGILTPQSADRIDEEADQQVSLAVDFADAGPAPGVETLFDHLYATEVANVFPGL
PGDPLPCEQAINRAQDGA
NT seq
1137 nt
NT seq
+upstream
nt +downstream
nt
atgagctcttcaccgacacctggccgcgatcccgccgccgacaccgcgggcacagcccgc
cccgcacccgccagtacggtctccgacagcgaggccgatgtgctgcgcggctactaccgg
cagatggcgctgatcagagctttcgagctgcgggcggcggagatgtacacccgggcgaag
atcggcggttactgccacctcaacctcggtgaggaagccacctgcgtcgggctgatggcc
gcactgcgatccaccgactacctgttcaccacctaccgggaacacggctacgccctcgcc
cgcggcgccgacccgggccgggtgatggcggagctgttcggacgcaccactggcatgtcc
ggcggacgcggcggctccatgcacctgttcgacaccgagctgcggctactcggcggctac
ggcatcgttggcggccaactgcccctggccaccggcgccgcgctggcgatctcctaccgc
ggcgagcccggatccggcagcgaggcggtgatgtgcctgctcggggacggcaccaccaac
atcggcgcgttccacgaggccctcaacctcgccgccgtatggcaccttcccatcgtctac
gtcatcgtcaacaaccaactcgggatgggcacccccgttgcggcggcggccggcgagccg
gagctgttccggcgcggctgcgcctaccgcatccccggaacccgcgtggacggaggcgac
gtactcgccgtgcgtgacgccgcccggatggcgctggagcaggcacgcgccgagcaccat
cccaggctgctggagacggtcagctaccggctgcgcggacactccgtcgtcgacccagcc
cgctaccgcaccccggaagaggccgcccagctgcgggagaaggacccggtgcccgccttg
cggatccgcctgatcgaggagggcatcctcaccccgcagtcggcggaccgcatcgacgag
gaggccgaccagcaggtcagccttgcggtcgacttcgccgacgcaggcccggccccgggt
gtggaaaccctcttcgaccacctgtacgccaccgaggtcgcaaacgtcttccccggcctg
ccgggcgatccactgccctgcgagcaggccattaaccgcgcacaggacggagcgtga
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