Streptomyces platensis: CP981_26365
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Entry
CP981_26365 CDS
T07341
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
spla
Streptomyces platensis
Pathway
spla00020
Citrate cycle (TCA cycle)
spla00630
Glyoxylate and dicarboxylate metabolism
spla00785
Lipoic acid metabolism
spla01100
Metabolic pathways
spla01110
Biosynthesis of secondary metabolites
spla01120
Microbial metabolism in diverse environments
spla01200
Carbon metabolism
spla01210
2-Oxocarboxylic acid metabolism
Module
spla_M00009
Citrate cycle (TCA cycle, Krebs cycle)
spla_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
spla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CP981_26365
00630 Glyoxylate and dicarboxylate metabolism
CP981_26365
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP981_26365
Enzymes [BR:
spla01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CP981_26365
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CP981_26365
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CP981_26365
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CP981_26365
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QEV54689
LinkDB
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Position
complement(5918900..5922688)
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AA seq
1262 aa
AA seq
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MSLQSPNSSSISTDQEGQGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GGATAPSQPAEGSAPAPAAPAQSAAPAAEPQSASAAPATPAKPAASAPAPAKAAPAKAEP
AKAAPAKPAAKPAAEEGSAPAGPEFITLRGPSAAVAKNMNASLELPTATSVRAVPVKLLF
DNRIVINNHLKRARGGKVSFTHLIGYAMVQALKAMPSMNYSFAEKDGKPTLVKPEHINLG
LAIDLVKPNGDRQLVVAAIKKAETLTFFEFWQAYEDIVRRARDNKLTMDDFTGVTASLTN
PGGIGTVHSVPRLMPGQSMIMGVGAMDYPAEFQGTSQDALNKLGVAKVMTLTSTYDHRVI
QGAASGEFLRIMSQLLLGDNEFFDDIFKSLRIPYEPVRWLRDIDASHDDDVTKAARVFEL
IHSYRVRGHVMADTDPLEYHQRKHPDLDITEHGLTLWDLEREFAVGGFSGKSMMKLRDIL
GVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERSHKSPEREEQLRILRRLNSAEAFETFL
QTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGKSYAQ
IFREFEGNLDPKSMHGSGDVKYHLGQEGVFTGLDGEQIKVSLAANPSHLEAVDPIVEGIA
RAKQDLINKGGTDFTVLPIQLHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHVVINNQVG
FTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLIC
YRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQLE
KVFTEVRDATTAPAAPEVPQPKAEFPVYVDTAISQEVVKRIAESQVNIPERVTVHPRLLP
QLQRRAAQVEDNTIDWGMGETLAIGSLLMEGTPVRLAGQDSRRGTFGQRHAVLIDRETGD
DYTPLLYLSEDQARFNVYDSLLSEYAAMGFEYGYSLARPEALVMWEAQFGDFVNGAQTVV
DEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARIERFLQLCAQNNMTVAMPTLPSNY
FHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASRTDEFTTGGFRPVIGDSTVKPEDVRKVI
FCSGKVYYDLEAEREKRGAHDTAIIRIERLYPLPGKELQAEISKFPNAEKYLWTQEEPAN
QGAWPFLGLNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQAQLVAEAF
DA
NT seq
3789 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgctacagtcccccaacagctcgagcatctcgaccgaccaggaggggcagggtaag
aaccctgctgctgcgttcggtcccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaactcggtagaccgagcctggtgggacttcttcgctgactacaagccg
ggcggtgccaccgcaccgagccagccggcggagggctctgcccccgctccggccgccccg
gcgcagtcggccgcgcccgcagccgagccgcagtcggcctccgccgcgccggccaccccg
gcgaagcccgccgcgagcgctccggcaccggcgaaggccgctccggcgaaggccgagccc
gcgaaggcggctccggccaagcccgccgcgaagccggccgccgaggagggctcggctccg
gccggtcccgagttcatcaccctgcgcggcccctcggccgccgttgcgaagaacatgaac
gcctccctggagctgccgacggccacgtccgtccgcgcggtcccggtgaagctgctcttc
gacaaccgcatcgtgatcaacaaccacctcaagcgcgcccgcggtgggaaggtctccttc
acccacctcatcgggtacgcgatggtgcaggccctcaaggccatgccgtcgatgaactac
tccttcgcggagaaggacggcaagccgacgctggtcaagcccgagcacatcaacctcggt
ctcgccatcgacctggtgaagccgaacggtgaccgccagctcgtcgtcgccgccatcaag
aaggccgagacgctgaccttcttcgagttctggcaggcctacgaggacatcgtccgccgg
gcccgcgacaacaagctgacgatggacgacttcaccggagtcaccgcgtcgctgacgaac
ccgggcggcatcggcaccgtgcactccgtgccccgcctgatgcccggccagtccatgatc
atgggcgtcggcgcgatggactaccccgcggagttccagggcacctcccaggacgccctg
aacaagctgggtgtcgccaaggtcatgacgctgaccagcacctatgaccaccgggtgatc
cagggcgccgcctccggcgagttcctgcgcatcatgagccagctgctgctcggcgacaac
gagttcttcgacgacatcttcaagtcgctgcggattccgtacgagcccgtccgctggctg
cgggacatcgacgcctcccacgacgacgacgtcaccaaggccgcccgggtcttcgagctg
atccactcctaccgggtccgcggccacgtcatggccgacaccgacccgctggagtaccac
cagcgcaagcaccccgacctcgacatcaccgagcacgggctcaccttgtgggacctggag
cgcgagttcgcggtcggcggcttctccggcaagtccatgatgaagctgcgcgacatcctg
ggcgtgctgcgtgactcgtactgccgcaccaccggcatcgagttcatgcacatccaggac
cccaagcagcgcaagtggatccaggaccgggtcgagcgctcgcacaagtcgcccgagcgc
gaggagcagctgcgcatcctgcgccggctgaactccgccgaggccttcgagaccttcctc
cagacgaagtacgtcggccagaagcgcttctcgctggagggcggcgagtccgtcatcccg
ctgctggacgcggtcatcgactccgcggccgagtcgcgcctcgacgaggtcgtcatcggc
atggcccaccgcggccgcctcaacgtcctggcgaacatcgtcggcaagtcgtacgcgcag
atcttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggctccggcgacgtg
aagtaccacctgggccaggagggtgtcttcaccggcctggacggcgagcagatcaaggtc
tcgctggccgcgaacccctcccacctggaggccgtcgacccgatcgtcgagggcatcgcg
cgcgccaagcaggacctcatcaacaagggcggcacggacttcacggtcctgccgatccag
ctgcacggtgacgcggcgttcgccggccagggcgtggtcgcggagacgctgaacatgtcc
cagctgcgcggctaccgcaccggcggcacggtgcacgtggtcatcaacaaccaggtcggc
ttcaccgccgccccggagtcgtcgcgttcgtccatgtacgccaccgacgtggcccgcatg
atcgaggcgccgatcttccacgtgaacggcgacgaccccgaggccgtcgtccgcgttgcc
cgtctggccttcgagttccgccaggcgttcaacaaggacgtcgtcatcgacctgatctgc
taccgccgccgtggccacaacgagtcggacaacccggccttcacccagccactgatgtac
gacctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtccctcatcggtcgc
ggcgacatcacgctggaagaggccgagcaggcgctccaggacttccagggccagctggag
aaggtcttcaccgaggtccgcgacgccacgacggccccggccgcccccgaggtgccgcag
cccaaggccgagttcccggtctacgtcgacaccgcgatctcccaggaggtcgtcaagcgg
atcgccgagtcgcaggtcaacatccccgagcgggtcaccgtccacccgcgtctgctgccc
cagctgcagcgccgcgcggcccaggtcgaggacaacaccatcgactggggcatgggcgag
accctggccatcggctcgctgctgatggagggcaccccggtccggctcgccggccaggac
tcccgccgtggcaccttcggccagcggcacgcggtgctcatcgaccgggagaccggcgac
gactacacgccgctgctctacctctccgaggaccaggcccgcttcaacgtctacgactcg
ctgctcagcgagtacgcggcgatgggcttcgagtacggctactccctggcccgtccggag
gcgctggtcatgtgggaggcgcagttcggtgacttcgtcaacggcgcccagacggtcgtc
gacgagttcatctcctcggcggagcagaagtggggccagacgtccggcgtcaccctgctg
ctgccgcacggctacgagggccagggcccggaccactcctcggcccgtatcgagcggttc
ctccagctgtgcgcgcagaacaacatgacggtcgccatgccgaccctgccgtcgaactac
ttccacctgctgcgctggcaggtccacaacccgcaccacaagccgctggtcgtcttcacc
ccgaagtcgatgctgcgtctgaaggcggcggcgtcgcggacggatgagttcacgacgggc
ggcttccgtcccgtcatcggcgactccacggtcaagcccgaggatgtccgcaaggtcatc
ttctgctccggcaaggtctactacgacctggaggccgagcgggagaagcgcggcgcgcac
gacaccgcgatcatccgtatcgagcggctctacccgcttcccggcaaggagctccaggcg
gagatctccaagttcccgaacgccgagaagtacctgtggacccaggaagaaccggcgaac
cagggtgcctggccgttcctcggcctcaacctgatcgaccacctcgacctggccgtcggc
gccgatgtcccgcacggcgagcgcctgcgccgcatctcgcggccgcactcctcgtcgccg
gccgtcggctccgccaagcgtcaccaggctgagcaggcacagctggtcgcggaggccttc
gacgcataa
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