Streptococcus pneumoniae gamPNI0373 (virulent serotype 1): HMPREF1038_00346
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Entry
HMPREF1038_00346 CDS
T02334
Symbol
sulB
Name
(GenBank) dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
spng
Streptococcus pneumoniae gamPNI0373 (virulent serotype 1)
Pathway
spng00790
Folate biosynthesis
spng01100
Metabolic pathways
spng01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
spng00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HMPREF1038_00346 (sulB)
Enzymes [BR:
spng01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HMPREF1038_00346 (sulB)
6.3.2.17 tetrahydrofolate synthase
HMPREF1038_00346 (sulB)
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GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Polysacc_deac_2
Motif
Other DBs
NCBI-ProteinID:
AFS42422
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Position
296862..298184
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AA seq
440 aa
AA seq
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MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHIGGTNGKGSTIAFLKKM
LEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADYQSLLEGEAVANLQDTTEF
EIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILTGITTIGLDHVALLGDTLEAI
AEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPRLAYGTDYQVRHQESVVTGEVFD
YTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQEDGRELASNDFLGQALEETSWPGRL
EIVSRDPLMILDGAHNPHAIKALLVTLQERFADYHKEILFTCIKTKALEDMLDLLGAMPD
TELTLTHFADSRATDESVLKEAAKSRNLSYQDWHDFLEQNLTDKKEEKQTVRIVTGSLYF
LSQVRAYLMERKNENGYTKD
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaaagaaattgaaaacaatcagtggattgctaactaccggacggatcaaccgcatttt
ggcttggaacgaatggtggaactgttagctttgcgtggcaatccccatctcaaactcaag
gtcctccatatcggagggactaacggcaagggatcgactattgcttttttgaaaaagatg
ctagaaaagctagggctgagagttggcgtgtttagctcgccctatctcattcattacaca
gaccagattagcatcaatggggaatcgatctcagaagcgaggctagaagctctcatggca
gactatcagtctttgctggagggagaagcggtcgccaatttacaggacacaaccgagttt
gagattatcacagccctggcctatgactactttgcctcagagcaagtagatgtggccatc
atggaagttggcatgggtggacttttggatagtaccaatgtctgtcagcccattttgaca
ggaattacaactattggcttggatcatgtggccctacttggtgacaccttggaggccata
gcagagcagaaggcaggtattatcaaacaagggatgcccttggtaacagggcgtattgct
ccagaagccttgactgtgattgaccgcattgcggaagggaaagatgcgccgagacttgcc
tacgggacagattatcaggttcgtcatcaagaaagtgtggtgacaggggaagtctttgac
tatacaagtgctgtcagacaaggtcgcttccagactagcctgcttggtttgtaccaaata
gagaatgctgggatggccatagctttacttgatactttttgtcaagaagatggtcgagag
ctagcaagcaatgactttcttggtcaagccttggaagaaacaagttggccagggcgtttg
gaaatcgtgtcaagagatcccttgatgattttggatggagcccacaatccccatgctatc
aaggccttgttggtaaccttgcaagaacgttttgcagattatcataaggaaatcctcttc
acttgtatcaaaaccaaggccttggaggatatgttggacttgttgggagccatgccagat
accgagcttactctaacacattttgcggatagtcgggcgacggatgaaagcgtgctgaaa
gaggcagctaagtctagaaatctcagctaccaagattggcatgattttctagagcagaat
ttgacagataaaaaagaagagaaacaaacagttaggattgtcacaggttccttgtatttc
ttgagccaagtgagggcctatctgatggagaggaagaacgagaatggatacacaaaagat
tga
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