Streptococcus pneumoniae gamPNI0373 (virulent serotype 1): HMPREF1038_01032
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Entry
HMPREF1038_01032 CDS
T02334
Name
(GenBank) TPP-dependent acetoin dehydrogenase complex, E1 component, alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
spng
Streptococcus pneumoniae gamPNI0373 (virulent serotype 1)
Pathway
spng00010
Glycolysis / Gluconeogenesis
spng00020
Citrate cycle (TCA cycle)
spng00620
Pyruvate metabolism
spng00785
Lipoic acid metabolism
spng01100
Metabolic pathways
spng01110
Biosynthesis of secondary metabolites
spng01120
Microbial metabolism in diverse environments
spng01200
Carbon metabolism
spng01210
2-Oxocarboxylic acid metabolism
Module
spng_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spng00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
HMPREF1038_01032
00020 Citrate cycle (TCA cycle)
HMPREF1038_01032
00620 Pyruvate metabolism
HMPREF1038_01032
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HMPREF1038_01032
Enzymes [BR:
spng01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
HMPREF1038_01032
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
AFS43084
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Position
939010..939978
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AA seq
322 aa
AA seq
DB search
MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVGEEAANVGAMLALNPDD
LITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMHIADLDAGNLGANGIVGGG
MGISVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNMASIWNLPVIFYCINNGYGIS
ADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEGFQKAVDHVRSGNGPVLIESVTY
RWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLIENNIASAEELEKIQAQVKEAVEAS
VKFAEESPFPPLESAFEDIYAD
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atgtcaactttagataaaaatcttttgctagaaatgttccgtaagatggaagaaatccgt
cgcatggacttaaaaattgcacaattagtaaagaaagggaaagtgccaggaatgacgcac
ttttctgttggtgaagaggcagctaacgtgggggctatgttagctctcaatccagatgat
ctgattacctcaaaccaccgtggacacgggcaagctattgctaaagggattgacctcaac
ggaatgatggctgaaatccttggtaaatacactggaacctgtaaagggaaaggtggatct
atgcatatcgctgaccttgatgctgggaaccttggtgccaatggtatcgtaggtggtggt
atggggatctctgtcggtgcagccctcagtcagcaaatgcaaaataccggtaaaatcgtt
gtctgcttctttggagatggtgcgaccaatgaaggtgttttccacgaagcagtgaacatg
gcttctatctggaacctgccagtcattttctattgcattaacaacggttacggtatctct
gcggatatcaagaaaatgaccaatatagaacatatccatcaacgtagcgccgcttatgga
attcctggaatgttcatcgaagacggtaacaatgtcatcgatgtctatgaaggatttcag
aaagctgtagaccatgttcgcagtggcaatggtccagtcttgattgaaagtgtaacttat
cgctggcttggtcactcatcatctgaccctggtaaatatcgtacgcgtgaagaagtggaa
ttgtggaaacaaaaagatccaatcgaaaacctccgcaattaccttattgaaaataacatt
gcaagtgccgaagaattggaaaaaatccaagcgcaagtaaaggaagcagtagaagcttct
gttaaatttgcagaggaaagcccattcccaccgcttgaatcagcctttgaagatatttac
gcagactaa
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