Streptococcus pneumoniae R6 (avirulent serotype 2): spr1051
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Entry
spr1051 CDS
T00060
Symbol
acoA
Name
(GenBank) TPP-dependent acetoin dehydrogenase alpha chain
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
spr
Streptococcus pneumoniae R6 (avirulent serotype 2)
Pathway
spr00010
Glycolysis / Gluconeogenesis
spr00020
Citrate cycle (TCA cycle)
spr00620
Pyruvate metabolism
spr00785
Lipoic acid metabolism
spr01100
Metabolic pathways
spr01110
Biosynthesis of secondary metabolites
spr01120
Microbial metabolism in diverse environments
spr01200
Carbon metabolism
spr01210
2-Oxocarboxylic acid metabolism
Module
spr_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
spr1051 (acoA)
00020 Citrate cycle (TCA cycle)
spr1051 (acoA)
00620 Pyruvate metabolism
spr1051 (acoA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
spr1051 (acoA)
Enzymes [BR:
spr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
spr1051 (acoA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
AAK99855
UniProt:
Q8DPQ7
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All DBs
Position
complement(1046292..1047260)
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AA seq
322 aa
AA seq
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MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVGEEAANVGAMLALNPDD
LITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMHIADLDAGNLGANGIVGGG
MGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNMASIWNLPVIFYCINNGYGIS
ADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEGFQKAVDHVRSGNGPVLIESVTY
RWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLIENNIASAEELEKIQAQVKEAVEAS
VKFAEESPFPPLESAFEDIYTD
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atgtcaactttagataaaaatcttttgctagaaatgttccgtaagatggaagaaatccgt
cgcatggacttaaaaattgcacaattagtaaagaaagggaaagtgccaggaatgacgcac
ttttctgttggtgaagaggcagctaacgtgggggctatgttagctctcaatccagatgat
ctgattacctcaaaccaccgtggacacgggcaagctattgctaaagggattgacctcaac
ggaatgatggctgaaatccttggtaaatacactggaacctgtaaagggaaaggtggatct
atgcatatcgctgaccttgatgctgggaaccttggtgccaatggtatcgtaggtggtggt
atggggatcgctgtcggtgcagccctcagtcagcaaatgcaaaataccggtaaaatcgtt
gtttgcttctttggagatggtgcgaccaatgaaggtgttttccacgaagcagtgaacatg
gcttctatctggaacctgccagtcattttctattgcattaacaacggttacggtatctct
gcggatatcaagaaaatgaccaatatagaacatatccatcaacgtagcgccgcttatgga
attcctggaatgttcatcgaagacggtaacaatgtcatcgatgtctatgaaggatttcag
aaagctgtagaccatgttcgcagtggcaatggtccagtcttgattgaaagtgtaacttat
cgctggcttggtcactcatcatctgaccctggtaaatatcgtacgcgtgaagaagtggaa
ttgtggaaacaaaaagatccaatcgaaaacctccgcaattaccttattgaaaataacatt
gcaagtgccgaagaattggaaaaaatccaagcgcaagtaaaggaagcagtagaagcttct
gttaaatttgcagaggaaagcccattcccaccgcttgaatcagcctttgaagatatttac
acagactaa
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