Streptomyces prasinus: CP972_12405
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Entry
CP972_12405 CDS
T07676
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
spra
Streptomyces prasinus
Pathway
spra00790
Folate biosynthesis
spra01100
Metabolic pathways
spra01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
spra00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CP972_12405
Enzymes [BR:
spra01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CP972_12405
6.3.2.17 tetrahydrofolate synthase
CP972_12405
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QEV06367
UniProt:
A0A5J6GYH0
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Position
complement(2702163..2703722)
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AA seq
519 aa
AA seq
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MSDLPPNGTPGDPDDRPDPLYPLDSSDSLDSFEEIIEAETQRDPDLAVIEAGSRTLRTQG
GPPESDVPARPEDPEADKALREVEGELAGRWGETKLEPSLDRVAALMDVLGEPQRAYPSI
HITGTNGKTSTARMIEALLGAFELRTGRYTSPHVQSVTERISLDGAPVSAERFVETYRDI
APYVEMVDARQEHRLSFFEVLTGMAYAAFADAPVDAAVVEVGMGGSWDATNVIDAGVAVV
MPIDLDHTDRLGTTPAEIATEKAGIIKPDATVIMAQQPVDAAQVLLRKAVEVGATVAREG
LEFGVVTRQVAVGGQQLTLRGLGGEYPEVYLPLHGAHQAHNAAVALAAVEAFFGVGAQRA
EPLDIDTVRKAFAAVASPGRLEVVRRSPTVVLDAAHNPAGARAAAGAIGEAFQFSRLIGV
VGASGDKNVRGLLEAFEPVFAEVVVTQNSTHRAMDADELAGIAVEVFGEDRVQVEPRLPD
ALEAAITLAEEEGEFTGAGVLVTGSVITVGEARLLLGKG
NT seq
1560 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgacctccccccgaacggcacccccggcgaccccgacgaccggccggaccccctg
taccccctcgactcctccgactccctcgactccttcgaggagatcatcgaggccgagacc
cagcgggaccccgacctcgcggtgatcgaggccggcagccgcaccctgcgcacgcagggc
ggcccgcccgagtccgacgtgcccgcgcggccggaggaccccgaggccgacaaggcgctg
cgggaggtcgagggggagctggcgggccgctggggcgagaccaagctggagccgtccctc
gaccgggtcgccgcgctgatggacgtcctgggcgagccgcagcgcgcgtacccgtcgatc
cacatcaccggcaccaacggcaagacctccaccgcccgcatgatcgaggccctcctcggc
gccttcgaactgcgcaccgggcgctacacctcgccgcacgtccagtcggtcaccgagcgg
atcagcctcgacggcgcgccggtctccgccgagcggttcgtggagacgtaccgggacatc
gcgccgtacgtcgagatggtcgacgcgcggcaggagcaccggctgtccttcttcgaggtg
ctcaccggcatggcgtacgcggccttcgccgacgcgccggtggacgctgccgtcgtcgag
gtcggcatgggcggcagctgggacgccaccaacgtgatcgacgccggcgtcgccgtggtc
atgccgatcgacctcgaccacaccgaccggctcggcaccacgcccgccgagatcgccacc
gagaaggccggcatcatcaagccggacgcgaccgtgatcatggcccagcagccggtcgac
gcggcccaggtgctgctgaggaaggccgtcgaggtcggcgcgaccgtggcccgggaaggg
ctggagttcggcgtcgtcacccggcaggtcgccgtcggcggccagcagctgaccctgcgc
ggcctgggcggcgagtaccccgaggtgtacctgccgctgcacggcgcccaccaggcgcac
aacgccgccgtggcgctcgccgccgtggaggcgttcttcggcgtcggcgcccagcgcgcc
gagccgctggacatcgacaccgtccgcaaggccttcgccgccgtcgcctcaccgggccgg
ctggaggtcgtccgacggtcgcccaccgtcgtgctggacgccgcccacaacccggcgggc
gcgcgggccgcggccggggcgatcggggaggccttccagttcagccggctcatcggcgtg
gtcggcgcgagcggcgacaagaacgtgcgcgggctgctggaggccttcgagccggtcttc
gccgaggtcgtcgtcacgcagaactccacccaccgcgcgatggacgccgacgaactggcg
gggatcgccgtcgaggtgttcggcgaggaccgcgtccaggtcgaaccccggctgcccgac
gcgctggaggcggcgatcacgctcgccgaggaggagggcgagttcaccggcgccggtgtg
ctcgtcaccggttccgtcatcacggtcggcgaggcccggctgcttctggggaagggctga
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