Streptococcus pneumoniae CGSP14 (serotype 14): SPCG_0303
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Entry
SPCG_0303 CDS
T00690
Symbol
sulB
Name
(GenBank) dihydrofolate synthetase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
spw
Streptococcus pneumoniae CGSP14 (serotype 14)
Pathway
spw00790
Folate biosynthesis
spw01100
Metabolic pathways
spw01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
spw00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
SPCG_0303 (sulB)
Enzymes [BR:
spw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
SPCG_0303 (sulB)
6.3.2.17 tetrahydrofolate synthase
SPCG_0303 (sulB)
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Gene cluster
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Polysacc_deac_2
Motif
Other DBs
NCBI-ProteinID:
ACB89555
UniProt:
B2ISL8
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All DBs
Position
294010..295332
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AA seq
440 aa
AA seq
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MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHIGGTNGKGSTIAFLKKM
LEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADYQSLLEGEAVANLQGTTEF
EIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILTGITTIGLDHVALLGDTLEAI
AEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPRLAYGTDYQVRHQESVVTGEVFD
YTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQEDGRELASNDFLGQALEETSWPGRL
EIVSRDPLMILDGAHNPHAIKALLVTLQERFADYHKEILFTCIKTKALGDMLDLLGAMPD
TELTLTHFADSRATDESVLKEAAKSRNLSYQDWHDFLEQNLTDKKEEKQTVRIVTGSLYF
LSQVRAYLMERKNENGYTKD
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaaagaaattgaaaacaatcagtggattgctaactaccggacggatcaaccgcatttt
ggcttggaacgaatggtggaactgttagctttgcgtggcaatccccatcttaaactcaag
gttctccatatcggagggactaacggcaagggctcgactattgcttttttgaaaaagatg
ctagaaaagctagggctgagagttggcgtgtttagttcgccctatctcattcattacaca
gaccagattagcatcaatggggaatcgatctcagaagcgaggctagaagctctcatggca
gactatcagtctttgctggagggagaagcggtcgccaatttacagggcacaaccgagttt
gagattatcacagccctagcctatgactactttgcctcagagcaagtagatgtggctatc
atggaagttggcatgggtggacttttggatagtaccaatgtctgtcagcccattttgaca
ggaattacaactattggcttggatcatgtggccctacttggtgacaccttggaggccata
gcagagcagaaggcaggtattatcaaacaagggatgcccttggtaacagggcgtattgct
ccagaagccttgactgtgattgaccgcattgcggaagggaaagatgcgccgagacttgcc
tacgggacagattatcaggttcgtcatcaagaaagtgtggtgacaggggaagtctttgac
tatacaagtgctgtcagacaaggtcgcttccagactagcctgcttggtttgtaccaaata
gagaatgctgggatggccatagctttacttgatactttttgtcaagaagatggtcgagag
ctagcaagcaatgactttcttggtcaagccttggaagaaacaagttggccagggcgtttg
gaaatcgtgtcaagagatcccttgatgattttggatggagcccataatccccatgctatc
aaggccttgttggtaaccttgcaagaacgttttgcggattatcataaggaaatcctcttc
acttgtatcaaaaccaaagccttgggggatatgttggacttgctgggagctatgccagat
accgagcttactctaacacattttgcggatagtcgggcgacggatgaaagcgtgctgaaa
gaggcagctaagtctagaaatctcagctaccaagattggcatgattttctagagcagaat
ttgacagataaaaaagaagagaaacaaacagttaggattgtcacaggttccttgtatttc
ttgagccaagtgagggcctatctgatggagaggaagaacgagaatggatacacaaaagat
tga
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