Streptococcus pyogenes M1 GAS (serotype M1): SPy_1026
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Entry
SPy_1026 CDS
T00050
Symbol
acoA
Name
(GenBank) putative acetoin dehydrogenase (TPP-dependent) alpha chain
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
spy
Streptococcus pyogenes M1 GAS (serotype M1)
Pathway
spy00010
Glycolysis / Gluconeogenesis
spy00020
Citrate cycle (TCA cycle)
spy00620
Pyruvate metabolism
spy00785
Lipoic acid metabolism
spy01100
Metabolic pathways
spy01110
Biosynthesis of secondary metabolites
spy01120
Microbial metabolism in diverse environments
spy01200
Carbon metabolism
spy01210
2-Oxocarboxylic acid metabolism
Module
spy_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spy00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
SPy_1026 (acoA)
00020 Citrate cycle (TCA cycle)
SPy_1026 (acoA)
00620 Pyruvate metabolism
SPy_1026 (acoA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SPy_1026 (acoA)
Enzymes [BR:
spy01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
SPy_1026 (acoA)
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AAK33920
UniProt:
Q99ZX8
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All DBs
Position
834559..835527
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AA seq
322 aa
AA seq
DB search
MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVGEEAANVGAVAHLSYDD
IIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMHLADFEKGNYGTNGIVGGG
YALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNMAATWKLPVIFFIINNRYGIS
MSINNATNTPHLYTRAEAYGVPGFYCEDGNDVMAVYETMGKAVEHVRGGNGPAIVEVESY
RWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLTSEGIATDDELDAIQAQVKKEVDDA
YEFAQNSPDPELSVAFEDVWVD
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atggtaacagtttctaaagaacaacatttagatatgttccttaaaatggaacgtattcgt
gaatttgattcacgtattaataaactcgtccgtcgtggatttgtacaagggatgactcac
ttctcagttggtgaagaagcagccaatgttggagcggtggctcacttgtcttacgatgac
attattttttcaaatcaccgtggacatggacaatcaatcgctaaagacatggaccttaat
aaaatgatggctgagcttgctggtaaagcaactggtgtgtctaaagggcgtggtggctca
atgcacttggctgattttgaaaaaggaaactatggtactaatggtatcgttggtggtggt
tacgctcttgcagttggtgctgccctcactcaacaatacaaaggaactaacaatatagct
gttgctttctcaggtgatggcgctactaacgaaggatcattccacgagtctgttaatatg
gctgcaacatggaaacttcctgttattttcttcatcatcaacaaccgttatggaatttca
atgagcatcaataatgcaacaaatacaccacacttatacacacgtgcagaagcttacgga
gttcctggtttctactgtgaagatggcaatgacgtgatggctgtctatgaaacaatgggc
aaagccgttgaacatgttcgtggtggaaatggtccagctattgttgaggtagaatcatac
cgttggtttggtcactcgactgcagatgctggtaaataccgtactaaagaagaagtggat
gagtggaaagaaaaagatccaatgatcaaatatcgtacttatctgacaagcgaaggcatt
gccactgatgacgaattggatgctattcaagcacaagtcaaaaaagaagttgacgatgct
tatgaatttgcacaaaacagtccagatccagaactttcagtagccttcgaagacgtttgg
gttgactaa
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