Streptococcus pyogenes A20 (serotype M1): A20_0794
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Entry
A20_0794 CDS
T02335
Symbol
acoA
Name
(GenBank) dehydrogenase E1 component family protein
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
spya
Streptococcus pyogenes A20 (serotype M1)
Pathway
spya00010
Glycolysis / Gluconeogenesis
spya00020
Citrate cycle (TCA cycle)
spya00620
Pyruvate metabolism
spya00785
Lipoic acid metabolism
spya01100
Metabolic pathways
spya01110
Biosynthesis of secondary metabolites
spya01120
Microbial metabolism in diverse environments
spya01200
Carbon metabolism
spya01210
2-Oxocarboxylic acid metabolism
Module
spya_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spya00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
A20_0794 (acoA)
00020 Citrate cycle (TCA cycle)
A20_0794 (acoA)
00620 Pyruvate metabolism
A20_0794 (acoA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
A20_0794 (acoA)
Enzymes [BR:
spya01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
A20_0794 (acoA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AFV37876
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Position
751847..752815
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AA seq
322 aa
AA seq
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MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVGEEAANVGAVAHLSYDD
IIFSNHRGHGQSIAKDMDLNKMMAELAGKATGVSKGRGGSMHLADFEKGNYGTNGIVGGG
YALAVGAALTQQYKGTNNIAVAFSGDGATNEGSFHESVNMAATWKLPVIFFIINNRYGIS
MSINNATNTPHLYTRAEAYGVPGFYCEDGNDVMAVYETMGKAVEHVRGGNGPAIVEVESY
RWFGHSTADAGKYRTKEEVDEWKEKDPMIKYRTYLTSEGIATDDELDAIQAQVKKEVDDA
YEFAQNSPDPELSVAFEDVWVD
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atggtaacagtttctaaagaacaacatttagatatgttccttaaaatggaacgtattcgt
gaatttgattcacgtattaataaactcgtccgtcgtggatttgtacaagggatgactcac
ttctcagttggtgaagaagcagccaatgttggagcggtggctcacttgtcttacgatgac
attattttttcaaatcaccgtggacatggacaatcaatcgctaaagacatggaccttaat
aaaatgatggctgagcttgctggtaaagcaactggtgtgtctaaagggcgtggtggctca
atgcacttggctgattttgaaaaaggaaactatggtactaatggtatcgttggtggtggt
tacgctcttgcagttggtgctgccctcactcaacaatacaaaggaactaacaatatagct
gttgctttctcaggtgatggcgctactaacgaaggatcattccacgagtctgttaatatg
gctgcaacatggaaacttcctgttattttcttcatcatcaacaaccgttatggaatttca
atgagcatcaataatgcaacaaatacaccacacttatacacacgtgcagaagcttacgga
gttcctggtttctactgtgaagatggcaatgacgtgatggctgtctatgaaacaatgggc
aaagccgttgaacatgttcgtggtggaaatggtccagctattgttgaggtagaatcatac
cgttggtttggtcactcgactgcagatgctggtaaataccgtactaaagaagaagtggat
gagtggaaagaaaaagatccaatgatcaaatatcgtacttatctgacaagcgaaggcatt
gccactgatgacgaattggatgctattcaagcacaagtcaaaaaagaagttgacgatgct
tatgaatttgcacaaaacagtccagatccagaactttcagtagccttcgaagacgtttgg
gttgactaa
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