Streptococcus pyogenes M1 476 (serotype M1): M1GAS476_0053
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Entry
M1GAS476_0053 CDS
T02499
Symbol
purK
Name
(GenBank) phosphoribosylaminoimidazole carboxylase ATPase subunit
KO
K01589
5-(carboxyamino)imidazole ribonucleotide synthase [EC:
6.3.4.18
]
Organism
spym
Streptococcus pyogenes M1 476 (serotype M1)
Pathway
spym00230
Purine metabolism
spym01100
Metabolic pathways
spym01110
Biosynthesis of secondary metabolites
Module
spym_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
spym00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
M1GAS476_0053 (purK)
Enzymes [BR:
spym01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.18 5-(carboxyamino)imidazole ribonucleotide synthase
M1GAS476_0053 (purK)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
ATP-grasp
PurK_C
ATP-grasp_3
Dala_Dala_lig_C
2-Hacid_dh_C
F420_oxidored
Rossmann-like
3HCDH_N
NAD_binding_2
Motif
Other DBs
NCBI-ProteinID:
BAM29410
UniProt:
J7M6J5
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All DBs
Position
1:43102..44211
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AA seq
369 aa
AA seq
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MRNKEKSQRSQVVNSFKTIGIIGGGQLGQMMAIAAIYMGHKVITLDPASDSPASRVSEVI
VAPYDDVEALGQLAARCDVLTYEFENVDADGLDAVVSACQLPQGTDLLRISQNRIVEKDF
LANKAGVTVAPYKVVTSSLDLGGLDLTKTYVLKTETGGYDGHGQKIIRSAEDLPEAQQLA
NSAQCVLEEFVNFDLEISVIVSGNGKDVTVFPVQENIHRNNILSKTIVPARISDQLADKA
KKTAVQIAKKLQLSGTLCVEMFTTADDIIVNEIAPRPHNSGRYSIEACDFSQFDTHILGV
LGAPLPQIQLHAPAVMLNVLGQHVQQATDYVAKNPSAHLHMYGKLEAKHNRKMGHVTVFA
KDADEVKEF
NT seq
1110 nt
NT seq
+upstream
nt +downstream
nt
atgaggaacaaggaaaaatcgcagaggagtcaagtggtgaactcatttaagaccattggg
attatcggtggtggtcagctggggcagatgatggccattgcggctatctatatgggtcac
aaggtcatcacgctggatcctgctagcgacagccctgcctcccgcgttagcgaggtaatt
gtggcgccttacgatgatgttgaggctttgggacaattggctgcgcgttgcgatgtgttg
acttatgagtttgagaatgttgatgcggacggtttggatgccgttgtgtcagcttgtcag
ctaccgcaggggaccgatctgctccgcatttcccaaaaccgtatcgttgaaaaagacttt
ctggcaaataaggctggtgtgacagtcgctccctataaggtggtgacgtctagccttgac
ctaggggggcttgatttgaccaagacctatgtcctcaagacagagacaggtggttatgac
ggtcatgggcaaaagattatccgctcagcagaagatttgccagaggcgcagcaattagct
aactcagctcagtgtgtcttggaagagtttgtcaactttgaccttgaaatctcagtcatc
gtgtctggaaatggcaaggatgtgacggtctttcccgttcaggaaaatatccaccgcaac
aatatcctgtcaaaaaccatcgtaccagctcgcatctcagatcaactggctgataaggct
aagaaaacggcggtgcagattgccaagaaactccagctgtcaggaactctctgtgtggaa
atgtttacgaccgcagatgatatcattgtcaatgaaattgccccacgcccccacaactca
gggcgctattctatcgaagcctgcgacttttcacagtttgacacccacatcttgggtgtg
ttgggcgcaccacttcctcagattcagctccacgccccagccgtcatgctcaatgtccta
ggacaacatgtccagcaggcaactgactatgttgccaaaaaccctagcgcccacctccac
atgtatggtaaactagaagcgaaacataaccgcaaaatgggacatgtgacggtgtttgca
aaagatgcggatgaggtgaaggagttttaa
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