KEGG   Streptococcus pyogenes MGAS5005 (serotype M1): M5005_Spy0325
Entry
M5005_Spy0325     CDS       T00262                                 
Symbol
murE
Name
(GenBank) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--lysine ligase
  KO
K05362  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7]
Organism
spz  Streptococcus pyogenes MGAS5005 (serotype M1)
Pathway
spz00550  Peptidoglycan biosynthesis
spz01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:spz00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    M5005_Spy0325 (murE)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:spz01011]
    M5005_Spy0325 (murE)
Enzymes [BR:spz01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.7  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---L-lysine ligase
     M5005_Spy0325 (murE)
Peptidoglycan biosynthesis and degradation proteins [BR:spz01011]
 Precursor biosynthesis
  Amino acid ligase
   M5005_Spy0325 (murE)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C
Other DBs
NCBI-ProteinID: AAZ50944
UniProt: Q9A196
LinkDB
Position
complement(331240..332685)
AA seq 481 aa
MITIEQLLDILKKDHNFREVLDADGYHYHYQGFSFERLSYDSRQVDGKTLFFAKGATFKA
DYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIAMAFYGNPQEKLKLLAFTGTK
GKTTAAYFAYHMLKESYKPAMFSTMNTTLDGKTFFKSQLTTPESLDLFAMMAECVTNGMT
HLIMEVSSQAYLVDRVYGLTFDVGVFLNISPDHIGPIEHPTFEDYFYHKRLLMENSRAVV
INSGMDHFSFLADQVADQEHVFYGPLSDNQITTSQAFSFEAKGQLAGHYDIQLIGHFNQE
NAMAAGLACLRLGASLADIQKGIAKTRVPGRMEVLTMTNHAKVFVDYAHNGDSLEKLLSV
VEEHQTGKLMLILGAPGNKGESRRADFGRVIHQHPNLTVILTADDPNFEDPEDISKEIAS
HIARPVEIISDREQAIQKAMSLCQGAKDAVIIAGKGADAYQIVKGQQVAYAGDLAIAKHY
L
NT seq 1446 nt   +upstreamnt  +downstreamnt
atgataaccattgaacaattattagacattttaaaaaaagaccataattttcgtgaggtt
cttgatgccgacggataccactaccattatcaaggctttagttttgagcgcttgagttac
gatagccgtcaagtagatggcaagacccttttttttgctaaaggggcaactttcaaagct
gactaccttaaagaagcaatcactaacggattacaactctatatttcagaggtagattac
gagcttggtattcccgttgttttggtcactgatatcaaaaaagctatgagtctaattgcc
atggctttctatggcaaccctcaagaaaagctcaaactactagcttttacaggtactaag
ggaaagacgacggctgcttattttgcctaccacatgttgaaagaatcctataaacctgcc
atgttttctaccatgaataccaccttagatggcaagacctttttcaaatcacaactcaca
actcctgagagcttggatctttttgctatgatggctgagtgtgtgactaatggcatgacc
cacttgattatggaagtttctagtcaggcttacctcgttgaccgtgtctatgggcttacg
ttcgatgttggggttttcctaaatattagtcctgatcatattggcccaatcgagcatcca
acgtttgaagattatttctatcataagcgtcttttaatggagaatagcagagctgttgtg
atcaatagcgggatggatcatttttcatttctagcggatcaggtagcggatcaagagcat
gtgttttatggtcccttgtctgacaaccagatcaccactagccaagccttctcctttgaa
gctaaaggacaattagctggccattatgacattcaattaattggccattttaaccaagaa
aatgctatggcagctggacttgcctgccttcgtttgggtgctagcctagctgatattcaa
aaaggtatcgctaagactcgcgtcccaggccgtatggaagtcctcactatgacaaatcat
gctaaagtttttgttgattatgcccataatggtgacagcttagaaaaattactcagcgtt
gtggaagaacatcagacaggcaaattaatgttgattttaggtgcaccaggaaataaaggc
gagagcagacgagctgattttggtagggtgattcatcagcatccaaacctcaccgtcatt
ctcactgctgatgaccctaatttcgaggatccagaagatatttcaaaagaaattgccagc
catatcgcacgcccagtagagattattagtgaccgtgagcaagctattcaaaaagccatg
tctctttgccaaggagcaaaagatgctgtgattatcgctgggaaaggcgcagatgcttat
caaattgttaaaggacaacaagtagcttatgctggtgatttagcaatcgccaaacactac
ctctag

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