KEGG   Serratia quinivorans: E4343_24110
Entry
E4343_24110       CDS       T05941                                 
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
  KO
K11754  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
Organism
squ  Serratia quinivorans
Pathway
squ00790  Folate biosynthesis
squ01100  Metabolic pathways
squ01240  Biosynthesis of cofactors
Module
squ_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:squ00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    E4343_24110 (folC)
Enzymes [BR:squ01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12  dihydrofolate synthase
     E4343_24110 (folC)
    6.3.2.17  tetrahydrofolate synthase
     E4343_24110 (folC)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C MeaB
Other DBs
NCBI-ProteinID: QBX69056
LinkDB
Position
5123361..5124623
AA seq 420 aa
MQNHQIPQATSPLSSWLFYLERLHSQAIELGLERVQRVAAHLDLLTPAPTVFTVAGTNGK
GTTCRTLETILMAAGLRVGVYSSPHLVRYTERVRIQGDELSEAEHCRSFAAIEAGRGETS
LTYFEFGTLSALQLFKQAKLDVVILEVGLGGRLDATNIVDPSVAVVTSIALDHTDWLGND
RESIGREKAGIFRSGKPAVVGEPDMPATIGQVAETLGAQLYRRGDAWSFSEQGERWQWQG
GGTLLTDLPMPNVPLANAATALAALHFSALEIDERAIFTGLQQATLPGRFQIVRRDPMLI
LDVAHNPHAAGYLAGRLATLPRNGGKVRAVVGMLSDKDIAGTLACLSEQVDEWYCAPLDG
PRGASVELLAQYLTEPRQFADVETAWRQAMQDADIQDIVIVCGSFHTVAQVMAALDERGV
NT seq 1263 nt   +upstreamnt  +downstreamnt
atgcaaaaccaccaaattccccaagccacgtcgccattgagctcgtggcttttctatctg
gaacgtctgcacagccaggcgatcgaactcggcctggaacgcgtacagcgcgttgcggcg
catcttgatttactcactcctgcaccgacggtatttaccgtagccgggaccaatggcaaa
ggcaccacctgtcgcaccctggaaaccatcctgatggcggccggtttgcgcgttggcgtc
tacagctcgccgcacctggtgcgttataccgagcgggtgcgcattcagggcgatgaactg
agtgaggccgaacactgccgctcgttcgccgccattgaagcgggccggggcgaaacttca
ctgacttacttcgaatttggcaccctgtcggcgctgcaactgttcaaacaggctaagctt
gacgtggtgatcctggaagtcgggctgggtggccgcctggatgcgaccaacatcgtcgat
ccgagcgtggcagtggtgaccagcattgcgctggatcataccgactggctgggcaacgat
cgcgaaagcattggccgtgaaaaggccgggatcttccgcagcggcaaaccggcggtggtg
ggggaaccggatatgccggccaccattgggcaggtggcggaaacgctgggtgcccaactg
tatcgccgcggcgatgcctggagcttcagcgaacagggcgaacgctggcagtggcaaggc
ggcggtaccttgctgaccgatttgccgatgcccaacgtaccgttagccaatgcggcgacg
gcactggctgcgctgcatttttctgcgttggaaattgatgagcgtgcaatcttcaccggc
ttgcagcaggcgacattacctggacgtttccagattgtgcgacgcgatccgatgctgatc
ctcgacgtggcgcataatccccacgcggcaggttacctggccgggcgtctggcgacctta
ccgcgcaatggcggcaaagtgcgagcggtggtggggatgttgtcggataaagacatcgcc
ggcaccctggcctgtttgagtgagcaggtcgatgagtggtattgcgcgccgctggacggg
ccgcgcggggccagcgtcgaactgttggcgcaatatttgacggaaccgcggcagtttgcc
gatgtcgaaactgcctggcgtcaggctatgcaggacgcagatattcaggatattgtgatc
gtctgtggatcgttccacaccgttgcacaggttatggcggcgttagacgagcggggagtg
tga

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