Streptomyces rapamycinicus: M271_23675
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Entry
M271_23675 CDS
T02907
Name
(GenBank) phosphoribosylglycinamide synthetase
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
src
Streptomyces rapamycinicus
Pathway
src00230
Purine metabolism
src01100
Metabolic pathways
src01110
Biosynthesis of secondary metabolites
Module
src_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
src00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
M271_23675
Enzymes [BR:
src01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
M271_23675
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
TruB-C_2
Motif
Other DBs
NCBI-ProteinID:
AGP51599
LinkDB
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Position
complement(5893581..5895830)
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AA seq
749 aa
AA seq
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MTLDTTKHAAQTPEAEQPWAELGLKQEEYERVRAILGRRPTGAELAMYSVMWSEHCSYKS
SKVHLRQFGEKAPESDALLVGIGENAGVVDVGQGYAVTFKVESHNHPSYVEPYQGAATGV
GGIVRDILAMGARPVAVMDPLRFGAADHPDTKRVLPGVVAGIGGYGNCLGLPNIGGEVVF
DPCYQGNPLVNALCVGVMKHADIHLAKASGTGNKVILYGARTGGDGIGGVSVLASETFDD
SKPTKRPAVQVGDPFQEKLLIECTLEVFKEDLVEGIQDLGGAGLSCATSELASAGSGGMR
VELDTVPLRDSSLSPEEILMSESQERMCAIVKPEKVDRFLEICEKWDVIATVIGEVTDGE
RLEIYWHGEQIVDVPPRTVAHEGPVYERPYARPEWQDALQADDAGKLPRPATAAELREQI
LKVIGSPNQSSKSWITDQYDRFVQGNTVLAQPEDSGMVRVDEETGLGVAVATDGNGRYAK
LDPYAGAQLALAESYRNVAASGAKPLAISNCLNFGSPEDPAVMWQFAEATRGLADGCLTL
GTPVTGGNVSLYNQTGEVAIHPTPVVAVLGVIDDVARRTPIAFAEEGQLLYLLGDTAAEL
GGSAWSQVIHDHLGGLPPKVDLERERLLAEILISASRDGMVDAAHDLSDGGLIQALAESC
LRGGKGARIVVPDGLDPFVLLFSESAGRAIVAVPRSEEVRFNDMCGARGLPAARIGVVDG
DAIDVQGQFSIPLAELRESYEATIPGLLA
NT seq
2250 nt
NT seq
+upstream
nt +downstream
nt
atgaccctggacaccaccaagcacgcggcgcagaccccggaggccgagcagccctgggcc
gagctcggtctcaagcaggaggagtacgagcgcgtccgcgccatcctgggccgccgcccc
accggtgccgagctcgcgatgtactccgtcatgtggtccgagcactgctcgtacaagtcg
agcaaggtccatctgcggcagttcggtgagaaggcccccgagagcgacgcgctgctcgtc
ggcatcggcgagaacgcgggtgtggtcgacgtcggccagggctacgcggtcaccttcaag
gtcgagtcgcacaaccacccctcgtacgtcgagccctaccagggcgcggccaccggcgtc
ggcggcatcgtccgcgacatcctcgccatgggcgcccgcccggtggccgtgatggacccg
ctgcgcttcggcgccgccgaccaccccgacaccaagcgggtgctgcccggtgtggtcgcg
ggcatcggcggctacggcaactgcctgggcctgcccaacatcggcggcgaggtcgtcttc
gacccctgctaccagggcaacccgctggtcaacgcgttgtgcgtgggcgtgatgaagcat
gcggacatccacctcgccaaggcgtccggcaccggcaacaaggtgatcctctacggcgcc
cgcaccggcggcgacggcatcggcggcgtctccgtgctggcctccgagacgtttgacgac
agtaagcccaccaagcgtcccgccgtccaggtcggcgaccccttccaggagaagctgctc
atcgagtgcaccctggaggtcttcaaggaggacctggtcgagggcattcaggacctcggc
ggcgcgggcctgtcctgcgccaccagcgagctcgccagcgccggctccggcggtatgcgg
gtcgagctcgacaccgtgccgctgcgcgactcctcgctctcccccgaggagatcctgatg
agtgagtcgcaggagcgcatgtgcgcgatcgtgaagcccgagaaggtcgaccgcttcctg
gagatctgcgagaagtgggacgtcatcgccactgtcatcggtgaggtcaccgacggcgag
cggctggagatctactggcacggcgagcagatcgtggacgtcccgccgcgcaccgtcgcc
catgagggcccggtctacgagcgcccctacgcccgccccgagtggcaggacgcgctccag
gcggacgacgcgggcaagctgccgcgcccggccacggcggcggagctgcgcgagcagatc
ctcaaggtgatcggctccccgaaccagtcgtccaagtcctggatcacggaccagtacgac
cgcttcgtgcagggcaacacggtgctcgcccagcccgaggactccggcatggtccgggtg
gacgaggagaccggcctgggtgtggccgtcgccacggacggcaacggccgctacgccaag
ctggacccgtacgcgggcgcgcagctcgcgctcgccgagtcgtaccgcaatgtggccgcg
tccggcgccaagccactggccatctccaactgtctcaacttcggctcgccggaggacccc
gcggtcatgtggcagttcgcggaggccacccgcggtctcgcggacggctgtctgaccctg
ggcaccccggtcaccggcggcaatgtgtcgctgtacaaccagaccggtgaggtggccatc
cacccgacgccggtcgtcgccgtcctcggcgtgatcgacgatgtggcccgccgcaccccg
atcgccttcgcggaggagggtcagctgctctatctgctgggcgacaccgccgcggagctg
ggcggctcggcctggtcccaggtgatccacgaccacttgggcggactgccgcccaaggtg
gacctggagcgggagcggctgctcgccgagatcctgatctcggcctcgcgcgacggcatg
gtggacgcggcccacgacctgtccgacggcggtctgatccaggcgctcgccgagtcgtgt
ctgcgcgggggcaagggcgcccggatcgtcgtccccgacggtcttgaccccttcgtcctg
ctgttctccgagtccgcgggccgggcgatcgtcgccgtaccgcgcagcgaggaggtccgc
ttcaacgacatgtgcggggcccgggggctcccggcggcccgtatcggcgtggtcgacggc
gacgcgatcgacgtccaggggcagttctccatcccgctggccgagctgcgggagtcgtac
gaggcgacgatcccgggtctgctggcctga
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